ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	146/870	423/7206	6.17525426836e-36
ko04724	Glutamatergic synapse	76/870	152/7206	4.27829456902e-31
ko05033	Nicotine addiction	44/870	56/7206	1.99635681797e-30
ko04727	GABAergic synapse	58/870	110/7206	1.75197781143e-25
ko05032	Morphine addiction	58/870	110/7206	1.75197781143e-25
ko04723	Retrograde endocannabinoid signaling	69/870	175/7206	8.18257520884e-21
ko04728	Dopaminergic synapse	68/870	185/7206	1.423563005e-18
ko04721	Synaptic vesicle cycle	41/870	80/7206	9.48162147146e-18
ko04713	Circadian entrainment	55/870	136/7206	2.17304187199e-17
ko04725	Cholinergic synapse	60/870	160/7206	5.43026318638e-17
ko04024	cAMP signaling pathway	80/870	279/7206	2.45121847487e-14
ko04726	Serotonergic synapse	49/870	137/7206	3.59667304867e-13
ko04911	Insulin secretion	44/870	117/7206	7.91523293009e-13
ko04742	Taste transduction	28/870	61/7206	4.83216978876e-11
ko04020	Calcium signaling pathway	69/870	265/7206	2.47257902412e-10
ko04921	Oxytocin signaling pathway	57/870	209/7206	1.74742628657e-09
ko04261	Adrenergic signaling in cardiomyocytes	55/870	205/7206	5.23078602353e-09
ko04744	Phototransduction	18/870	36/7206	2.7161120495e-08
ko05031	Amphetamine addiction	30/870	91/7206	1.20372770186e-07
ko03040	Spliceosome	1/870	145/7206	2.23172382035e-07
ko05203	Viral carcinogenesis	9/870	277/7206	2.40366420346e-07
ko04720	Long-term potentiation	31/870	99/7206	2.7658938022e-07
ko05030	Cocaine addiction	25/870	73/7206	6.03475037139e-07
ko04514	Cell adhesion molecules (CAMs)	36/870	130/7206	9.61126131982e-07
ko04970	Salivary secretion	29/870	95/7206	1.21021571481e-06
ko04360	Axon guidance	54/870	233/7206	1.67146704475e-06
ko04060	Cytokine-cytokine receptor interaction	5/870	191/7206	4.36036129334e-06
ko04972	Pancreatic secretion	30/870	111/7206	1.30776772629e-05
ko04010	MAPK signaling pathway	65/870	321/7206	2.13346825339e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/870	79/7206	3.56770607562e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	22/870	74/7206	3.68056085997e-05
ko05168	Herpes simplex infection	6/870	182/7206	4.26898870142e-05
ko03013	RNA transport	5/870	166/7206	5.28931986451e-05
ko05164	Influenza A	5/870	167/7206	5.41062982249e-05
ko05322	Systemic lupus erythematosus	4/870	151/7206	6.5462953774e-05
ko04072	Phospholipase D signaling pathway	43/870	197/7206	8.5035112648e-05
ko04925	Aldosterone synthesis and secretion	27/870	105/7206	0.000105875441944
ko04141	Protein processing in endoplasmic reticulum	7/870	184/7206	0.000129323000223
ko04621	NOD-like receptor signaling pathway	5/870	157/7206	0.000156783196189
ko04022	cGMP-PKG signaling pathway	45/870	216/7206	0.000182431072647
ko04120	Ubiquitin mediated proteolysis	4/870	138/7206	0.000184302351673
ko04260	Cardiac muscle contraction	25/870	98/7206	0.000224614875928
ko04971	Gastric acid secretion	25/870	98/7206	0.000224614875928
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/870	59/7206	0.000418933529602
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/870	14/7206	0.000580937905708
ko03008	Ribosome biogenesis in eukaryotes	1/870	79/7206	0.000751740762065
ko05205	Proteoglycans in cancer	16/870	271/7206	0.000817692728588
ko05414	Dilated cardiomyopathy	26/870	112/7206	0.00103509214694
ko04730	Long-term depression	20/870	78/7206	0.00121330573285
ko04964	Proximal tubule bicarbonate reclamation	10/870	29/7206	0.00144570574294
ko05169	Epstein-Barr virus infection	11/870	206/7206	0.00151903885497
ko04014	Ras signaling pathway	51/870	279/7206	0.00192632648907
ko04350	TGF-beta signaling pathway	3/870	103/7206	0.00194433386018
ko04966	Collecting duct acid secretion	9/870	26/7206	0.00241508683387
ko04915	Estrogen signaling pathway	28/870	131/7206	0.00252598937253
ko04976	Bile secretion	19/870	80/7206	0.00295506685941
ko00240	Pyrimidine metabolism	4/870	110/7206	0.00300423073496
ko04540	Gap junction	27/870	128/7206	0.00358125929947
ko04064	NF-kappa B signaling pathway	3/870	96/7206	0.00393521196512
ko05162	Measles	5/870	120/7206	0.00437265242852
ko04630	Jak-STAT signaling pathway	6/870	132/7206	0.00439344851642
ko04070	Phosphatidylinositol signaling system	24/870	112/7206	0.00484037361946
ko04217	Necroptosis	10/870	178/7206	0.0049867086801
ko04640	Hematopoietic cell lineage	1/870	64/7206	0.00567795609352
ko05140	Leishmaniasis	2/870	75/7206	0.00688200116307
ko04612	Antigen processing and presentation	2/870	77/7206	0.00716128106777
ko04924	Renin secretion	19/870	86/7206	0.00723461883315
ko05145	Toxoplasmosis	6/870	126/7206	0.00820581776141
ko05161	Hepatitis B	10/870	173/7206	0.00881993742389
ko04214	Apoptosis - fly	2/870	72/7206	0.0099442553808
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/870	182/7206	0.0106522490318
ko03018	RNA degradation	3/870	84/7206	0.0109454797953
ko04930	Type II diabetes mellitus	13/870	54/7206	0.0112942758632
ko00480	Glutathione metabolism	1/870	55/7206	0.0117727847201
ko05321	Inflammatory bowel disease (IBD)	1/870	56/7206	0.0119012995742
ko04110	Cell cycle	8/870	145/7206	0.013583278928
ko04510	Focal adhesion	17/870	240/7206	0.0151227724133
ko00590	Arachidonic acid metabolism	1/870	52/7206	0.0173811373333
ko04371	Apelin signaling pathway	32/870	177/7206	0.0187543580111
ko05110	Vibrio cholerae infection	14/870	63/7206	0.019025747166
ko01200	Carbon metabolism	7/870	128/7206	0.019048759493
ko05410	Hypertrophic cardiomyopathy (HCM)	20/870	100/7206	0.019749845886
ko04745	Phototransduction - fly	10/870	38/7206	0.019890966958
ko04146	Peroxisome	4/870	89/7206	0.0216810013566
ko00515	Mannose type O-glycan biosynthesis	7/870	25/7206	0.0247951506904
ko04750	Inflammatory mediator regulation of TRP channels	23/870	122/7206	0.0249177013531
ko05219	Bladder cancer	1/870	48/7206	0.0254975015008
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/870	15/7206	0.0269950897771
ko00330	Arginine and proline metabolism	2/870	61/7206	0.0290413366302
ko04140	Autophagy - animal	11/870	164/7206	0.0291408784991
ko05133	Pertussis	4/870	87/7206	0.0299586980874
ko00310	Lysine degradation	3/870	73/7206	0.0301203984825
ko01524	Platinum drug resistance	3/870	76/7206	0.0312300704389
ko04668	TNF signaling pathway	7/870	120/7206	0.0332172131438
ko04740	Olfactory transduction	16/870	80/7206	0.0370570644201
ko00071	Fatty acid degradation	1/870	45/7206	0.0374492297176
ko00620	Pyruvate metabolism	1/870	46/7206	0.0379518042988
ko03420	Nucleotide excision repair	1/870	46/7206	0.0379518042988
ko05131	Shigellosis	4/870	82/7206	0.0406567265649
ko04137	Mitophagy - animal	4/870	82/7206	0.0406567265649
ko04270	Vascular smooth muscle contraction	27/870	154/7206	0.0444179806231
ko04210	Apoptosis	13/870	180/7206	0.0478627906968
ko00562	Inositol phosphate metabolism	17/870	89/7206	0.048533107118