ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	48/441	152/7206	1.50696310608e-22
ko05033	Nicotine addiction	25/441	56/7206	2.28934461653e-16
ko04080	Neuroactive ligand-receptor interaction	68/441	423/7206	4.48178803884e-14
ko04727	GABAergic synapse	30/441	110/7206	1.3375009655e-12
ko05032	Morphine addiction	30/441	110/7206	1.3375009655e-12
ko04723	Retrograde endocannabinoid signaling	38/441	175/7206	3.05210944222e-12
ko04024	cAMP signaling pathway	48/441	279/7206	3.09905422838e-11
ko04261	Adrenergic signaling in cardiomyocytes	38/441	205/7206	4.43514329802e-10
ko04911	Insulin secretion	27/441	117/7206	1.14564288184e-09
ko04713	Circadian entrainment	29/441	136/7206	1.98602141135e-09
ko04720	Long-term potentiation	24/441	99/7206	3.42305631638e-09
ko05030	Cocaine addiction	20/441	73/7206	7.39115716873e-09
ko04020	Calcium signaling pathway	42/441	265/7206	7.56977353062e-09
ko04728	Dopaminergic synapse	33/441	185/7206	1.77630091875e-08
ko04072	Phospholipase D signaling pathway	34/441	197/7206	2.5369574303e-08
ko04010	MAPK signaling pathway	45/441	321/7206	1.22283031982e-07
ko05031	Amphetamine addiction	20/441	91/7206	4.00497671682e-07
ko04742	Taste transduction	16/441	61/7206	4.63831356868e-07
ko04925	Aldosterone synthesis and secretion	21/441	105/7206	1.08591691662e-06
ko04921	Oxytocin signaling pathway	32/441	209/7206	1.10852369045e-06
ko05414	Dilated cardiomyopathy	21/441	112/7206	3.25461120519e-06
ko00515	Mannose type O-glycan biosynthesis	9/441	25/7206	9.39638561142e-06
ko04725	Cholinergic synapse	25/441	160/7206	1.18197209165e-05
ko04514	Cell adhesion molecules (CAMs)	21/441	130/7206	3.5623202729e-05
ko04915	Estrogen signaling pathway	21/441	131/7206	4.00658287112e-05
ko04970	Salivary secretion	17/441	95/7206	5.26303152326e-05
ko04022	cGMP-PKG signaling pathway	29/441	216/7206	6.18459876426e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/441	79/7206	7.13684189701e-05
ko04740	Olfactory transduction	15/441	80/7206	8.3009264915e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/441	14/7206	0.000100008204875
ko04923	Regulation of lipolysis in adipocytes	14/441	77/7206	0.000200710182467
ko04721	Synaptic vesicle cycle	14/441	80/7206	0.00030440921617
ko04912	GnRH signaling pathway	18/441	122/7206	0.000409557183659
ko04360	Axon guidance	27/441	233/7206	0.0011949587641
ko04744	Phototransduction	8/441	36/7206	0.0012203975374
ko04930	Type II diabetes mellitus	10/441	54/7206	0.00139466963883
ko05168	Herpes simplex infection	2/441	182/7206	0.00144463258292
ko00512	Mucin type O-glycan biosynthesis	7/441	29/7206	0.00147181884019
ko04914	Progesterone-mediated oocyte maturation	15/441	104/7206	0.00154319885926
ko04726	Serotonergic synapse	18/441	137/7206	0.00180190138128
ko04971	Gastric acid secretion	14/441	98/7206	0.00240083915419
ko05203	Viral carcinogenesis	6/441	277/7206	0.00295992970082
ko00513	Various types of N-glycan biosynthesis	8/441	42/7206	0.0034477005037
ko04211	Longevity regulating pathway	16/441	123/7206	0.0036299906851
ko04972	Pancreatic secretion	15/441	111/7206	0.00382320835803
ko05014	Amyotrophic lateral sclerosis (ALS)	11/441	74/7206	0.00501204868535
ko04213	Longevity regulating pathway - multiple species	12/441	86/7206	0.00581161670925
ko04114	Oocyte meiosis	17/441	139/7206	0.00610815772161
ko04012	ErbB signaling pathway	14/441	109/7206	0.00735954271211
ko05410	Hypertrophic cardiomyopathy (HCM)	13/441	100/7206	0.00936196016475
ko04320	Dorso-ventral axis formation	6/441	31/7206	0.0100965775294
ko00510	N-Glycan biosynthesis	8/441	50/7206	0.0102280482632
ko04750	Inflammatory mediator regulation of TRP channels	15/441	122/7206	0.0111025979804
ko01522	Endocrine resistance	15/441	124/7206	0.0118448772092
ko05213	Endometrial cancer	9/441	62/7206	0.01244372592
ko04110	Cell cycle	2/441	145/7206	0.0125813854563
ko03013	RNA transport	3/441	166/7206	0.0132317820519
ko00240	Pyrimidine metabolism	1/441	110/7206	0.0144707922819
ko04371	Apelin signaling pathway	19/441	177/7206	0.0158829143041
ko04270	Vascular smooth muscle contraction	17/441	154/7206	0.0161229240971
ko04260	Cardiac muscle contraction	12/441	98/7206	0.0179273296934
ko04145	Phagosome	3/441	162/7206	0.0186797448425
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	5/441	26/7206	0.0189528338397
ko04350	TGF-beta signaling pathway	1/441	103/7206	0.0208843261141
ko01200	Carbon metabolism	2/441	128/7206	0.0241435627429
ko04142	Lysosome	3/441	151/7206	0.0253203795206
ko04670	Leukocyte transendothelial migration	3/441	151/7206	0.0253203795206
ko04070	Phosphatidylinositol signaling system	13/441	112/7206	0.0255563981651
ko00601	Glycosphingolipid biosynthesis - lacto and neolacto series	5/441	28/7206	0.0256238884866
ko05231	Choline metabolism in cancer	15/441	134/7206	0.0261320136633
ko04722	Neurotrophin signaling pathway	17/441	160/7206	0.0277243676196
ko04976	Bile secretion	10/441	80/7206	0.0295500998818
ko04916	Melanogenesis	15/441	142/7206	0.0329441676164
ko05020	Prion diseases	6/441	40/7206	0.0331804840794
ko04540	Gap junction	14/441	128/7206	0.0371608258115
ko04146	Peroxisome	1/441	89/7206	0.0433409868783
ko04144	Endocytosis	30/441	342/7206	0.0481336985731