ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	149/979	423/7206	1.15882057421e-31
ko05033	Nicotine addiction	43/979	56/7206	7.50971286347e-27
ko04724	Glutamatergic synapse	73/979	152/7206	3.80512445888e-25
ko05032	Morphine addiction	56/979	110/7206	4.43371085411e-21
ko04728	Dopaminergic synapse	72/979	185/7206	2.73242204579e-18
ko04713	Circadian entrainment	59/979	136/7206	7.90214072058e-18
ko04727	GABAergic synapse	51/979	110/7206	4.59970669889e-17
ko04721	Synaptic vesicle cycle	41/979	80/7206	6.91723412493e-16
ko04723	Retrograde endocannabinoid signaling	64/979	175/7206	7.74708547429e-15
ko04024	cAMP signaling pathway	87/979	279/7206	7.830627407e-15
ko04725	Cholinergic synapse	60/979	160/7206	1.48601370396e-14
ko04921	Oxytocin signaling pathway	69/979	209/7206	2.69122592499e-13
ko04020	Calcium signaling pathway	80/979	265/7206	7.35746910344e-13
ko04911	Insulin secretion	43/979	117/7206	1.86312553957e-10
ko04726	Serotonergic synapse	47/979	137/7206	4.01506127796e-10
ko05031	Amphetamine addiction	36/979	91/7206	5.38764993948e-10
ko04742	Taste transduction	27/979	61/7206	4.34724751169e-09
ko04720	Long-term potentiation	36/979	99/7206	7.96546625721e-09
ko04261	Adrenergic signaling in cardiomyocytes	59/979	205/7206	9.35088228546e-09
ko04744	Phototransduction	19/979	36/7206	2.4967016544e-08
ko03010	Ribosome	1/979	129/7206	1.83584973784e-07
ko03040	Spliceosome	2/979	145/7206	2.4668808546e-07
ko04970	Salivary secretion	31/979	95/7206	2.23553880321e-06
ko04010	MAPK signaling pathway	73/979	321/7206	5.43405204842e-06
ko05030	Cocaine addiction	25/979	73/7206	5.45605838392e-06
ko05322	Systemic lupus erythematosus	4/979	151/7206	5.94584665405e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/979	74/7206	7.19492568897e-06
ko05203	Viral carcinogenesis	15/979	277/7206	1.00439194884e-05
ko04745	Phototransduction - fly	16/979	38/7206	1.40942096117e-05
ko04360	Axon guidance	56/979	233/7206	1.45711126136e-05
ko04925	Aldosterone synthesis and secretion	31/979	105/7206	1.7632864683e-05
ko04514	Cell adhesion molecules (CAMs)	36/979	130/7206	2.26355002036e-05
ko04022	cGMP-PKG signaling pathway	52/979	216/7206	2.77558999712e-05
ko04070	Phosphatidylinositol signaling system	32/979	112/7206	3.39368272074e-05
ko05168	Herpes simplex infection	8/979	182/7206	6.36704763124e-05
ko04971	Gastric acid secretion	28/979	98/7206	7.90709191832e-05
ko04710	Circadian rhythm	16/979	43/7206	8.63761799124e-05
ko04060	Cytokine-cytokine receptor interaction	9/979	191/7206	9.41752026127e-05
ko04740	Olfactory transduction	24/979	80/7206	0.000105981218262
ko04730	Long-term depression	23/979	78/7206	0.000192258980883
ko04621	NOD-like receptor signaling pathway	7/979	157/7206	0.000225537476583
ko04626	Plant-pathogen interaction	9/979	18/7206	0.000233463452595
ko04966	Collecting duct acid secretion	11/979	26/7206	0.000301562784599
ko04072	Phospholipase D signaling pathway	45/979	197/7206	0.000306580840132
ko03013	RNA transport	8/979	166/7206	0.000325874486742
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/979	79/7206	0.000348049744168
ko04260	Cardiac muscle contraction	26/979	98/7206	0.000534267711519
ko04120	Ubiquitin mediated proteolysis	6/979	138/7206	0.000593658851828
ko04014	Ras signaling pathway	58/979	279/7206	0.000667700141778
ko05164	Influenza A	9/979	167/7206	0.000831644399288
ko03008	Ribosome biogenesis in eukaryotes	2/979	79/7206	0.00143906520385
ko05161	Hepatitis B	10/979	173/7206	0.00149642111346
ko04915	Estrogen signaling pathway	31/979	131/7206	0.00174890656881
ko05169	Epstein-Barr virus infection	14/979	206/7206	0.00262135101448
ko05166	HTLV-I infection	23/979	292/7206	0.00289246126746
ko04630	Jak-STAT signaling pathway	7/979	132/7206	0.00296677434413
ko04110	Cell cycle	8/979	145/7206	0.00297485153619
ko05140	Leishmaniasis	2/979	75/7206	0.00324891223745
ko04064	NF-kappa B signaling pathway	4/979	96/7206	0.00394198672662
ko00562	Inositol phosphate metabolism	22/979	89/7206	0.00443654769027
ko05110	Vibrio cholerae infection	17/979	63/7206	0.00456988481351
ko04972	Pancreatic secretion	26/979	111/7206	0.00470071403796
ko00480	Glutathione metabolism	1/979	55/7206	0.0050407543532
ko05205	Proteoglycans in cancer	22/979	271/7206	0.00647102952806
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/979	14/7206	0.00703020141629
ko04610	Complement and coagulation cascades	3/979	79/7206	0.00738496373326
ko04540	Gap junction	28/979	128/7206	0.00882454595308
ko05162	Measles	7/979	120/7206	0.0100765512352
ko04750	Inflammatory mediator regulation of TRP channels	27/979	122/7206	0.0105104581646
ko04612	Antigen processing and presentation	3/979	77/7206	0.010795540155
ko05410	Hypertrophic cardiomyopathy (HCM)	23/979	100/7206	0.0113948752604
ko04964	Proximal tubule bicarbonate reclamation	9/979	29/7206	0.0119685199741
ko04330	Notch signaling pathway	2/979	62/7206	0.0138206828043
ko04214	Apoptosis - fly	3/979	72/7206	0.0146233613714
ko04924	Renin secretion	20/979	86/7206	0.0160509190911
ko03420	Nucleotide excision repair	1/979	46/7206	0.0164607184633
ko00270	Cysteine and methionine metabolism	1/979	47/7206	0.0167137827237
ko05219	Bladder cancer	1/979	48/7206	0.0173366378087
ko04371	Apelin signaling pathway	35/979	177/7206	0.0192849399423
ko04711	Circadian rhythm - fly	5/979	13/7206	0.0229822040053
ko00240	Pyrimidine metabolism	7/979	110/7206	0.0240498778694
ko03022	Basal transcription factors	1/979	44/7206	0.0247190140565
ko05414	Dilated cardiomyopathy	24/979	112/7206	0.0248112217345
ko00071	Fatty acid degradation	1/979	45/7206	0.0256223023661
ko00280	Valine, leucine and isoleucine degradation	2/979	54/7206	0.0277525877276
ko04146	Peroxisome	5/979	89/7206	0.0277769338392
ko05321	Inflammatory bowel disease (IBD)	2/979	56/7206	0.0286100118158
ko04141	Protein processing in endoplasmic reticulum	15/979	184/7206	0.0287729737866
ko05200	Pathways in cancer	51/979	492/7206	0.0292190317377
ko04015	Rap1 signaling pathway	50/979	278/7206	0.0321566031177
ko05230	Central carbon metabolism in cancer	18/979	81/7206	0.032222368426
ko04722	Neurotrophin signaling pathway	31/979	160/7206	0.0354878297687
ko00980	Metabolism of xenobiotics by cytochrome P450	1/979	40/7206	0.0359037089025
ko04922	Glucagon signaling pathway	26/979	128/7206	0.0359518512389
ko05010	Alzheimer's disease	38/979	202/7206	0.0364509362913
ko04115	p53 signaling pathway	4/979	74/7206	0.0392710178301
ko04622	RIG-I-like receptor signaling pathway	3/979	62/7206	0.0402254642263
ko00680	Methane metabolism	9/979	34/7206	0.0405503905358
ko04350	TGF-beta signaling pathway	7/979	103/7206	0.0420165794165
ko04930	Type II diabetes mellitus	13/979	54/7206	0.0425137867882
ko05016	Huntington's disease	19/979	215/7206	0.0425735953193
ko04510	Focal adhesion	22/979	240/7206	0.0437697306774