ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	83/484	423/7206	4.11008913171e-20
ko04724	Glutamatergic synapse	39/484	152/7206	9.98370433005e-14
ko04020	Calcium signaling pathway	51/484	265/7206	3.0103632147e-12
ko05033	Nicotine addiction	20/484	56/7206	1.92783596282e-10
ko04727	GABAergic synapse	27/484	110/7206	2.06047021804e-09
ko05032	Morphine addiction	26/484	110/7206	9.72539937727e-09
ko04723	Retrograde endocannabinoid signaling	34/484	175/7206	1.18359947515e-08
ko04728	Dopaminergic synapse	34/484	185/7206	5.0601516864e-08
ko04713	Circadian entrainment	28/484	136/7206	6.58500939819e-08
ko04024	cAMP signaling pathway	43/484	279/7206	2.33838502811e-07
ko04726	Serotonergic synapse	25/484	137/7206	3.54024352371e-06
ko04725	Cholinergic synapse	27/484	160/7206	6.77693414066e-06
ko04720	Long-term potentiation	20/484	99/7206	6.92112992141e-06
ko05031	Amphetamine addiction	19/484	91/7206	7.08610324725e-06
ko04930	Type II diabetes mellitus	14/484	54/7206	8.42154044608e-06
ko04921	Oxytocin signaling pathway	32/484	209/7206	8.52548727306e-06
ko04010	MAPK signaling pathway	43/484	321/7206	1.02376832952e-05
ko04710	Circadian rhythm	12/484	43/7206	1.65402829116e-05
ko04022	cGMP-PKG signaling pathway	31/484	216/7206	4.56705851777e-05
ko04711	Circadian rhythm - fly	6/484	13/7206	0.00010170569121
ko04261	Adrenergic signaling in cardiomyocytes	29/484	205/7206	0.000104256479481
ko04072	Phospholipase D signaling pathway	28/484	197/7206	0.000130584510282
ko04070	Phosphatidylinositol signaling system	19/484	112/7206	0.000145964669546
ko04925	Aldosterone synthesis and secretion	18/484	105/7206	0.000189445246573
ko03013	RNA transport	1/484	166/7206	0.000217287309036
ko04721	Synaptic vesicle cycle	15/484	80/7206	0.000234053874042
ko04360	Axon guidance	31/484	233/7206	0.000247677535047
ko04911	Insulin secretion	19/484	117/7206	0.000263022215018
ko05030	Cocaine addiction	14/484	73/7206	0.000294171222637
ko05014	Amyotrophic lateral sclerosis (ALS)	14/484	74/7206	0.000340993876611
ko04514	Cell adhesion molecules (CAMs)	20/484	130/7206	0.000491920083868
ko04750	Inflammatory mediator regulation of TRP channels	18/484	122/7206	0.00141336519189
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/484	14/7206	0.00161210905218
ko04145	Phagosome	2/484	162/7206	0.00208944506185
ko05322	Systemic lupus erythematosus	2/484	151/7206	0.0043683631718
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/484	79/7206	0.00606132585233
ko00240	Pyrimidine metabolism	1/484	110/7206	0.00666542327186
ko04742	Taste transduction	10/484	61/7206	0.00689489591963
ko04915	Estrogen signaling pathway	17/484	131/7206	0.00750990203847
ko04071	Sphingolipid signaling pathway	20/484	162/7206	0.00983410205843
ko04972	Pancreatic secretion	15/484	111/7206	0.0108482564121
ko00430	Taurine and hypotaurine metabolism	4/484	14/7206	0.0117107582699
ko00190	Oxidative phosphorylation	2/484	127/7206	0.011883988938
ko05231	Choline metabolism in cancer	17/484	134/7206	0.0128812974403
ko04110	Cell cycle	3/484	145/7206	0.0180956442485
ko04012	ErbB signaling pathway	14/484	109/7206	0.0182229160212
ko04540	Gap junction	16/484	128/7206	0.0182308497949
ko05205	Proteoglycans in cancer	9/484	271/7206	0.0185277507284
ko04730	Long-term depression	11/484	78/7206	0.0187614492024
ko04014	Ras signaling pathway	29/484	279/7206	0.0194802386208
ko05323	Rheumatoid arthritis	1/484	89/7206	0.0301198680282
ko04970	Salivary secretion	12/484	95/7206	0.0348441178615
ko04916	Melanogenesis	16/484	142/7206	0.0398101057825
ko04912	GnRH signaling pathway	14/484	122/7206	0.0431299000274
ko03018	RNA degradation	1/484	84/7206	0.0441308294361
ko05010	Alzheimer's disease	21/484	202/7206	0.0442996281997
ko04142	Lysosome	4/484	151/7206	0.0464562213416
ko01200	Carbon metabolism	3/484	128/7206	0.0477444900404