ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 11/67 152/7206 1.19181532336e-07 ko05033 Nicotine addiction 7/67 56/7206 7.05894881981e-07 ko04020 Calcium signaling pathway 13/67 265/7206 7.19313432608e-07 ko04728 Dopaminergic synapse 10/67 185/7206 6.79486855037e-06 ko04727 GABAergic synapse 8/67 110/7206 7.04904750123e-06 ko05031 Amphetamine addiction 7/67 91/7206 1.90683162166e-05 ko05030 Cocaine addiction 6/67 73/7206 5.37533338155e-05 ko05032 Morphine addiction 7/67 110/7206 6.52369175713e-05 ko04080 Neuroactive ligand-receptor interaction 13/67 423/7206 0.00011273859034 ko04723 Retrograde endocannabinoid signaling 8/67 175/7206 0.000198097022471 ko04713 Circadian entrainment 7/67 136/7206 0.0002473768098 ko04720 Long-term potentiation 6/67 99/7206 0.000292935749435 ko04911 Insulin secretion 6/67 117/7206 0.00071754675715 ko04915 Estrogen signaling pathway 6/67 131/7206 0.00129549051469 ko05231 Choline metabolism in cancer 6/67 134/7206 0.00145594225888 ko04742 Taste transduction 4/67 61/7206 0.00239290923439 ko04010 MAPK signaling pathway 9/67 321/7206 0.00269646874358 ko04925 Aldosterone synthesis and secretion 5/67 105/7206 0.00281728334111 ko04022 cGMP-PKG signaling pathway 7/67 216/7206 0.00372801440952 ko04024 cAMP signaling pathway 8/67 279/7206 0.0040977856074 ko04666 Fc gamma R-mediated phagocytosis 5/67 122/7206 0.00535892145637 ko04973 Carbohydrate digestion and absorption 3/67 42/7206 0.00680886647392 ko04726 Serotonergic synapse 5/67 137/7206 0.00868217707603 ko04261 Adrenergic signaling in cardiomyocytes 6/67 205/7206 0.0116305996927 ko04725 Cholinergic synapse 5/67 160/7206 0.0162022036197 ko04012 ErbB signaling pathway 4/67 109/7206 0.0183110962495 ko04972 Pancreatic secretion 4/67 111/7206 0.0194435951436 ko05034 Alcoholism 6/67 238/7206 0.0227004240318 ko00512 Mucin type O-glycan biosynthesis 2/67 29/7206 0.0294226342126 ko05014 Amyotrophic lateral sclerosis (ALS) 3/67 74/7206 0.031173328621 ko00514 Other types of O-glycan biosynthesis 2/67 30/7206 0.0313380517477 ko04320 Dorso-ventral axis formation 2/67 31/7206 0.0333015700977 ko04730 Long-term depression 3/67 78/7206 0.0356444108671 ko04072 Phospholipase D signaling pathway 5/67 197/7206 0.0357528658107 ko05214 Glioma 3/67 79/7206 0.0368113698698 ko04740 Olfactory transduction 3/67 80/7206 0.037997888092 ko04015 Rap1 signaling pathway 6/67 278/7206 0.0437041294003 ko04014 Ras signaling pathway 6/67 279/7206 0.0443469910475 ko04918 Thyroid hormone synthesis 3/67 86/7206 0.0455238165279