ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	159/951	423/7206	1.63389720039e-39
ko05033	Nicotine addiction	45/951	56/7206	3.66289344874e-30
ko04724	Glutamatergic synapse	75/951	152/7206	1.32602170649e-27
ko05032	Morphine addiction	55/951	110/7206	7.48016490327e-21
ko04713	Circadian entrainment	62/951	136/7206	1.07900398222e-20
ko04728	Dopaminergic synapse	71/951	185/7206	2.28542591694e-18
ko04727	GABAergic synapse	51/951	110/7206	1.3038629297e-17
ko04024	cAMP signaling pathway	87/951	279/7206	1.29541087308e-15
ko04721	Synaptic vesicle cycle	40/951	80/7206	1.71506342398e-15
ko04723	Retrograde endocannabinoid signaling	64/951	175/7206	1.854309897e-15
ko04725	Cholinergic synapse	56/951	160/7206	9.4826871952e-13
ko04020	Calcium signaling pathway	78/951	265/7206	1.46306393971e-12
ko04911	Insulin secretion	45/951	117/7206	4.12816958933e-12
ko05031	Amphetamine addiction	38/951	91/7206	1.05820309858e-11
ko04921	Oxytocin signaling pathway	64/951	209/7206	2.34284996378e-11
ko04726	Serotonergic synapse	47/951	137/7206	1.47129175735e-10
ko04720	Long-term potentiation	37/951	99/7206	8.95631104755e-10
ko04742	Taste transduction	26/951	61/7206	1.19640651117e-08
ko04261	Adrenergic signaling in cardiomyocytes	56/951	205/7206	4.58479933721e-08
ko04970	Salivary secretion	32/951	95/7206	2.12206627407e-07
ko05030	Cocaine addiction	27/951	73/7206	2.20201728616e-07
ko03010	Ribosome	1/951	129/7206	4.78019117011e-07
ko04060	Cytokine-cytokine receptor interaction	5/951	191/7206	6.16863113022e-07
ko05203	Viral carcinogenesis	12/951	277/7206	7.62225463077e-07
ko04514	Cell adhesion molecules (CAMs)	38/951	130/7206	1.16799429048e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	26/951	74/7206	1.16945188135e-06
ko04925	Aldosterone synthesis and secretion	32/951	105/7206	2.93928166236e-06
ko03040	Spliceosome	3/951	145/7206	4.7182224132e-06
ko04745	Phototransduction - fly	16/951	38/7206	9.66767055332e-06
ko05322	Systemic lupus erythematosus	4/951	151/7206	1.37670837765e-05
ko04070	Phosphatidylinositol signaling system	32/951	112/7206	1.39788296598e-05
ko04971	Gastric acid secretion	29/951	98/7206	1.53627917113e-05
ko04744	Phototransduction	15/951	36/7206	2.13894544569e-05
ko04010	MAPK signaling pathway	69/951	321/7206	3.01970283081e-05
ko05168	Herpes simplex infection	7/951	182/7206	3.09661891496e-05
ko04730	Long-term depression	24/951	78/7206	5.3926095209e-05
ko04621	NOD-like receptor signaling pathway	6/951	157/7206	0.000110066895925
ko03013	RNA transport	7/951	166/7206	0.000168142812929
ko04740	Olfactory transduction	23/951	80/7206	0.000188995355582
ko04022	cGMP-PKG signaling pathway	48/951	216/7206	0.000207225863403
ko04360	Axon guidance	51/951	233/7206	0.00023521047327
ko04110	Cell cycle	6/951	145/7206	0.000433387602865
ko04214	Apoptosis - fly	1/951	72/7206	0.000698987391225
ko04120	Ubiquitin mediated proteolysis	6/951	138/7206	0.000834914454439
ko04710	Circadian rhythm	14/951	43/7206	0.000843721555028
ko04915	Estrogen signaling pathway	31/951	131/7206	0.000964294321632
ko04966	Collecting duct acid secretion	10/951	26/7206	0.00109782790286
ko04626	Plant-pathogen interaction	8/951	18/7206	0.00114892117397
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/951	79/7206	0.00122104245632
ko04064	NF-kappa B signaling pathway	3/951	96/7206	0.00124932098106
ko04072	Phospholipase D signaling pathway	42/951	197/7206	0.00127163537684
ko00562	Inositol phosphate metabolism	23/951	89/7206	0.00128048816884
ko04972	Pancreatic secretion	27/951	111/7206	0.00155982345268
ko05164	Influenza A	9/951	167/7206	0.0015982364415
ko04630	Jak-STAT signaling pathway	6/951	132/7206	0.00161823354706
ko03008	Ribosome biogenesis in eukaryotes	2/951	79/7206	0.00217302199754
ko04260	Cardiac muscle contraction	24/951	98/7206	0.00224882012431
ko05169	Epstein-Barr virus infection	13/951	206/7206	0.00226072785758
ko05166	HTLV-I infection	22/951	292/7206	0.00257566664043
ko04964	Proximal tubule bicarbonate reclamation	10/951	29/7206	0.00285522799702
ko05140	Leishmaniasis	2/951	75/7206	0.00312054061641
ko04330	Notch signaling pathway	1/951	62/7206	0.00369499935747
ko04014	Ras signaling pathway	53/951	279/7206	0.00503856796181
ko04141	Protein processing in endoplasmic reticulum	12/951	184/7206	0.00546020412279
ko04922	Glucagon signaling pathway	28/951	128/7206	0.00547157838575
ko05200	Pathways in cancer	45/951	492/7206	0.00564701302077
ko05162	Measles	6/951	120/7206	0.00591101556527
ko05161	Hepatitis B	11/951	173/7206	0.00595192461342
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/951	14/7206	0.00608052125548
ko04750	Inflammatory mediator regulation of TRP channels	27/951	122/7206	0.00635600588436
ko04924	Renin secretion	20/951	86/7206	0.00952446927151
ko05205	Proteoglycans in cancer	22/951	271/7206	0.0102064320049
ko04612	Antigen processing and presentation	3/951	77/7206	0.0104911454725
ko04610	Complement and coagulation cascades	3/951	79/7206	0.0108667112395
ko04510	Focal adhesion	19/951	240/7206	0.0115500538908
ko00590	Arachidonic acid metabolism	1/951	52/7206	0.011647865324
ko00240	Pyrimidine metabolism	6/951	110/7206	0.0147484928771
ko04657	IL-17 signaling pathway	4/951	87/7206	0.0154944756952
ko05219	Bladder cancer	1/951	48/7206	0.0168093756405
ko04960	Aldosterone-regulated sodium reabsorption	11/951	41/7206	0.0176590494859
ko04550	Signaling pathways regulating pluripotency of stem cells	12/951	165/7206	0.0197805186354
ko04973	Carbohydrate digestion and absorption	11/951	42/7206	0.0201757027779
ko05110	Vibrio cholerae infection	15/951	63/7206	0.022370020445
ko04540	Gap junction	26/951	128/7206	0.023994781378
ko04930	Type II diabetes mellitus	13/951	54/7206	0.0251597652673
ko03420	Nucleotide excision repair	1/951	46/7206	0.025599222569
ko05321	Inflammatory bowel disease (IBD)	2/951	56/7206	0.0281105276346
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/951	59/7206	0.0305110192409
ko05215	Prostate cancer	7/951	111/7206	0.0326344560041
ko04210	Apoptosis	14/951	180/7206	0.0331710196124
ko05010	Alzheimer's disease	37/951	202/7206	0.0345640911484
ko00140	Steroid hormone biosynthesis	1/951	41/7206	0.0362728201467
ko00680	Methane metabolism	9/951	34/7206	0.0365030449041
ko01524	Platinum drug resistance	4/951	76/7206	0.0396172137627
ko04640	Hematopoietic cell lineage	3/951	64/7206	0.0406525695508
ko00280	Valine, leucine and isoleucine degradation	2/951	54/7206	0.0407916942161
ko00480	Glutathione metabolism	2/951	55/7206	0.0419837230316
ko04976	Bile secretion	17/951	80/7206	0.0441277346359