ko pathway ratio_in_study ratio_in_pop p_value ko04070 Phosphatidylinositol signaling system 21/381 112/7206 2.98433821983e-07 ko04650 Natural killer cell mediated cytotoxicity 16/381 97/7206 4.19226236121e-05 ko04710 Circadian rhythm 10/381 43/7206 6.04768891179e-05 ko04060 Cytokine-cytokine receptor interaction 23/381 191/7206 0.000196961940486 ko04014 Ras signaling pathway 29/381 279/7206 0.000503599939178 ko04072 Phospholipase D signaling pathway 22/381 197/7206 0.000915024618617 ko05230 Central carbon metabolism in cancer 12/381 81/7206 0.0010323973175 ko04666 Fc gamma R-mediated phagocytosis 15/381 122/7206 0.00184123138721 ko04630 Jak-STAT signaling pathway 16/381 132/7206 0.00224627356445 ko03013 RNA transport 1/381 166/7206 0.00229814933014 ko00562 Inositol phosphate metabolism 12/381 89/7206 0.00236794038172 ko04380 Osteoclast differentiation 16/381 134/7206 0.00243387003317 ko05214 Glioma 11/381 79/7206 0.00274978104593 ko04659 Th17 cell differentiation 13/381 106/7206 0.00371503323157 ko04711 Circadian rhythm - fly 4/381 13/7206 0.00375591124065 ko04015 Rap1 signaling pathway 26/381 278/7206 0.0038750217832 ko04921 Oxytocin signaling pathway 21/381 209/7206 0.00417157247404 ko04020 Calcium signaling pathway 25/381 265/7206 0.00460927268445 ko04960 Aldosterone-regulated sodium reabsorption 7/381 41/7206 0.0051629361068 ko05231 Choline metabolism in cancer 15/381 134/7206 0.00523692932821 ko04662 B cell receptor signaling pathway 11/381 88/7206 0.00637211929711 ko03040 Spliceosome 1/381 145/7206 0.0072482299328 ko04110 Cell cycle 1/381 145/7206 0.0072482299328 ko04730 Long-term depression 10/381 78/7206 0.00763777169139 ko05167 Kaposi's sarcoma-associated herpesvirus infection 19/381 191/7206 0.00764398936526 ko04610 Complement and coagulation cascades 10/381 79/7206 0.00834617613287 ko04725 Cholinergic synapse 16/381 160/7206 0.0117795617484 ko04919 Thyroid hormone signaling pathway 15/381 143/7206 0.0119211912921 ko04010 MAPK signaling pathway 27/381 321/7206 0.0148576819539 ko00471 D-Glutamine and D-glutamate metabolism 2/381 4/7206 0.0155808269204 ko04140 Autophagy - animal 16/381 164/7206 0.0193639997502 ko04720 Long-term potentiation 11/381 99/7206 0.019427693806 ko05223 Non-small cell lung cancer 8/381 66/7206 0.0222338489824 ko05322 Systemic lupus erythematosus 2/381 151/7206 0.0250667823234 ko04925 Aldosterone synthesis and secretion 11/381 105/7206 0.0255729793268 ko05321 Inflammatory bowel disease (IBD) 7/381 56/7206 0.0271196031299 ko04022 cGMP-PKG signaling pathway 19/381 216/7206 0.0288302263225 ko04933 AGE-RAGE signaling pathway in diabetic complications 13/381 135/7206 0.0311430278165 ko04071 Sphingolipid signaling pathway 15/381 162/7206 0.031207575676 ko05166 HTLV-I infection 24/381 292/7206 0.0313039940894 ko04713 Circadian entrainment 13/381 136/7206 0.0323101086816 ko04144 Endocytosis 27/381 342/7206 0.0344330651026 ko04066 HIF-1 signaling pathway 12/381 123/7206 0.038310608308 ko04670 Leukocyte transendothelial migration 14/381 151/7206 0.0399989975719 ko05160 Hepatitis C 14/381 153/7206 0.0419532694168 ko04745 Phototransduction - fly 5/381 38/7206 0.0480976972567 ko05215 Prostate cancer 11/381 111/7206 0.0488971308131