ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04721	Synaptic vesicle cycle	49/811	80/7206	4.10501890417e-27
ko05033	Nicotine addiction	40/811	56/7206	3.34309854777e-26
ko04080	Neuroactive ligand-receptor interaction	119/811	423/7206	6.57555571017e-23
ko04724	Glutamatergic synapse	61/811	152/7206	1.54201811688e-20
ko04728	Dopaminergic synapse	62/811	185/7206	2.71590630992e-16
ko04727	GABAergic synapse	45/811	110/7206	8.09151042644e-16
ko05032	Morphine addiction	44/811	110/7206	4.58971757987e-15
ko04713	Circadian entrainment	47/811	136/7206	3.45950667081e-13
ko04723	Retrograde endocannabinoid signaling	53/811	175/7206	4.19456649163e-12
ko04725	Cholinergic synapse	49/811	160/7206	1.77611627755e-11
ko04024	cAMP signaling pathway	67/811	279/7206	7.76515287309e-10
ko04966	Collecting duct acid secretion	15/811	26/7206	1.21663202772e-08
ko04911	Insulin secretion	35/811	117/7206	2.84158177386e-08
ko04744	Phototransduction	17/811	36/7206	6.83902207427e-08
ko05031	Amphetamine addiction	29/811	91/7206	9.65290526881e-08
ko04360	Axon guidance	54/811	233/7206	1.33176262533e-07
ko04261	Adrenergic signaling in cardiomyocytes	48/811	205/7206	4.76730256501e-07
ko05030	Cocaine addiction	24/811	73/7206	6.49471680561e-07
ko04726	Serotonergic synapse	36/811	137/7206	7.23817592699e-07
ko03040	Spliceosome	1/811	145/7206	8.44103639096e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	24/811	74/7206	8.60620462521e-07
ko04514	Cell adhesion molecules (CAMs)	34/811	130/7206	1.66666034294e-06
ko04060	Cytokine-cytokine receptor interaction	4/811	191/7206	3.70671112289e-06
ko04720	Long-term potentiation	27/811	99/7206	7.76686239474e-06
ko04921	Oxytocin signaling pathway	45/811	209/7206	1.72835701588e-05
ko04742	Taste transduction	19/811	61/7206	2.28056705144e-05
ko05110	Vibrio cholerae infection	19/811	63/7206	3.78304201801e-05
ko05168	Herpes simplex infection	5/811	182/7206	3.98357768939e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/811	14/7206	4.01433739607e-05
ko04970	Salivary secretion	25/811	95/7206	4.35757968476e-05
ko03013	RNA transport	5/811	166/7206	0.000159318440182
ko05164	Influenza A	5/811	167/7206	0.000160908013356
ko04010	MAPK signaling pathway	58/811	321/7206	0.000195304101876
ko05203	Viral carcinogenesis	14/811	277/7206	0.000431964437511
ko04120	Ubiquitin mediated proteolysis	4/811	138/7206	0.000563326169707
ko05205	Proteoglycans in cancer	14/811	271/7206	0.000564967901291
ko05120	Epithelial cell signaling in Helicobacter pylori infection	22/811	92/7206	0.000627010876065
ko04964	Proximal tubule bicarbonate reclamation	10/811	29/7206	0.000833090766339
ko04730	Long-term depression	19/811	78/7206	0.000892804619641
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/811	79/7206	0.0010292836382
ko04621	NOD-like receptor signaling pathway	6/811	157/7206	0.00128109141699
ko04141	Protein processing in endoplasmic reticulum	8/811	184/7206	0.00130093379447
ko04020	Calcium signaling pathway	47/811	265/7206	0.00141138853065
ko04145	Phagosome	32/811	162/7206	0.00144881931938
ko05034	Alcoholism	43/811	238/7206	0.00160204556844
ko03008	Ribosome biogenesis in eukaryotes	1/811	79/7206	0.00179834707392
ko04915	Estrogen signaling pathway	27/811	131/7206	0.0018119925039
ko04626	Plant-pathogen interaction	7/811	18/7206	0.00231828832088
ko00310	Lysine degradation	1/811	73/7206	0.00256439958043
ko04260	Cardiac muscle contraction	21/811	98/7206	0.00322376780523
ko04146	Peroxisome	2/811	89/7206	0.0034847316313
ko04972	Pancreatic secretion	23/811	111/7206	0.00348611911441
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/811	15/7206	0.00407461305719
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/811	182/7206	0.00412488856222
ko04022	cGMP-PKG signaling pathway	38/811	216/7206	0.00434752589353
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/811	59/7206	0.00574477356705
ko05323	Rheumatoid arthritis	19/811	89/7206	0.00588214687255
ko04391	Hippo signaling pathway - fly	19/811	90/7206	0.00628592975047
ko04540	Gap junction	25/811	128/7206	0.00658436002014
ko04064	NF-kappa B signaling pathway	3/811	96/7206	0.00824516422783
ko00561	Glycerolipid metabolism	1/811	63/7206	0.00826201065719
ko04640	Hematopoietic cell lineage	1/811	64/7206	0.00839624818497
ko05162	Measles	5/811	120/7206	0.0085591637831
ko00240	Pyrimidine metabolism	4/811	110/7206	0.00876420376669
ko04971	Gastric acid secretion	20/811	98/7206	0.00882405484839
ko04350	TGF-beta signaling pathway	4/811	103/7206	0.0117107963694
ko05140	Leishmaniasis	2/811	75/7206	0.0151097192668
ko01200	Carbon metabolism	6/811	128/7206	0.0155128906668
ko05146	Amoebiasis	4/811	99/7206	0.0161787548411
ko00480	Glutathione metabolism	1/811	55/7206	0.0178271646004
ko05322	Systemic lupus erythematosus	8/811	151/7206	0.0182424252812
ko04014	Ras signaling pathway	44/811	279/7206	0.0199246396125
ko03018	RNA degradation	3/811	84/7206	0.0223826572195
ko04924	Renin secretion	17/811	86/7206	0.0234528750181
ko05169	Epstein-Barr virus infection	13/811	206/7206	0.0244335686451
ko00590	Arachidonic acid metabolism	1/811	52/7206	0.0261747105143
ko00280	Valine, leucine and isoleucine degradation	1/811	54/7206	0.0272439313835
ko04072	Phospholipase D signaling pathway	32/811	197/7206	0.0295423504093
ko04138	Autophagy - yeast	3/811	81/7206	0.0315759914456
ko04611	Platelet activation	10/811	163/7206	0.0330352004834
ko04140	Autophagy - animal	10/811	164/7206	0.0330587111029
ko05166	HTLV-I infection	22/811	292/7206	0.0376486553015
ko00512	Mucin type O-glycan biosynthesis	7/811	29/7206	0.0380194413627
ko04925	Aldosterone synthesis and secretion	19/811	105/7206	0.0409589475045
ko04612	Antigen processing and presentation	3/811	77/7206	0.0435722360924
ko05145	Toxoplasmosis	7/811	126/7206	0.0449614192896
ko04976	Bile secretion	15/811	80/7206	0.0474408903242