ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 33/256 145/7206 2.72813573205e-18 ko04110 Cell cycle 28/256 145/7206 1.00883126093e-13 ko04111 Cell cycle - yeast 21/256 90/7206 3.06017618959e-12 ko03008 Ribosome biogenesis in eukaryotes 19/256 79/7206 1.94617453159e-11 ko04113 Meiosis - yeast 15/256 70/7206 1.50917651802e-08 ko03013 RNA transport 23/256 166/7206 1.66079171215e-08 ko03460 Fanconi anemia pathway 11/256 51/7206 1.23848920631e-06 ko04080 Neuroactive ligand-receptor interaction 1/256 423/7206 4.43874917549e-06 ko05322 Systemic lupus erythematosus 18/256 151/7206 5.83883641568e-06 ko03440 Homologous recombination 9/256 41/7206 1.01217039734e-05 ko03015 mRNA surveillance pathway 13/256 93/7206 2.17114160813e-05 ko03018 RNA degradation 12/256 84/7206 3.61699995702e-05 ko04151 PI3K-Akt signaling pathway 2/256 390/7206 0.000111776019547 ko04114 Oocyte meiosis 15/256 139/7206 0.000113378242802 ko00240 Pyrimidine metabolism 13/256 110/7206 0.000129469414119 ko03020 RNA polymerase 6/256 29/7206 0.000452172304401 ko04024 cAMP signaling pathway 1/256 279/7206 0.000749096840346 ko04144 Endocytosis 2/256 342/7206 0.00076367816479 ko04010 MAPK signaling pathway 2/256 321/7206 0.00104052656635 ko04020 Calcium signaling pathway 1/256 265/7206 0.00108869101302 ko03410 Base excision repair 6/256 38/7206 0.00201079913695 ko03030 DNA replication 6/256 38/7206 0.00201079913695 ko04360 Axon guidance 1/256 233/7206 0.00341126489321 ko04510 Focal adhesion 1/256 240/7206 0.00362031102687 ko03022 Basal transcription factors 6/256 44/7206 0.00430521178907 ko04015 Rap1 signaling pathway 2/256 278/7206 0.00441259197156 ko04014 Ras signaling pathway 2/256 279/7206 0.00442784116258 ko04530 Tight junction 1/256 228/7206 0.00521382972938 ko04810 Regulation of actin cytoskeleton 2/256 264/7206 0.00626477640925 ko05205 Proteoglycans in cancer 2/256 271/7206 0.00643800742007 ko03430 Mismatch repair 4/256 22/7206 0.00686669323759 ko05203 Viral carcinogenesis 19/256 277/7206 0.00687919846868 ko04022 cGMP-PKG signaling pathway 1/256 216/7206 0.00750431971499 ko04120 Ubiquitin mediated proteolysis 11/256 138/7206 0.00982756481671 ko04914 Progesterone-mediated oocyte maturation 9/256 104/7206 0.0113678860429 ko05152 Tuberculosis 1/256 187/7206 0.0151138008677 ko04060 Cytokine-cytokine receptor interaction 1/256 191/7206 0.0153900575683 ko05167 Kaposi's sarcoma-associated herpesvirus infection 1/256 191/7206 0.0153900575683 ko05200 Pathways in cancer 8/256 492/7206 0.0156161306558 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/256 182/7206 0.022639704787 ko03420 Nucleotide excision repair 5/256 46/7206 0.0227515116655 ko04141 Protein processing in endoplasmic reticulum 1/256 184/7206 0.0231290750389 ko05034 Alcoholism 15/256 238/7206 0.0300842810727 ko04122 Sulfur relay system 2/256 8/7206 0.0305553818949 ko04611 Platelet activation 1/256 163/7206 0.0313947642857 ko04910 Insulin signaling pathway 1/256 172/7206 0.0330091631303 ko04142 Lysosome 1/256 151/7206 0.0451122063575 ko04670 Leukocyte transendothelial migration 1/256 151/7206 0.0451122063575 ko04722 Neurotrophin signaling pathway 1/256 160/7206 0.0470495671546 ko04115 p53 signaling pathway 6/256 74/7206 0.0470633793751 ko04072 Phospholipase D signaling pathway 2/256 197/7206 0.0491687970398 ko05166 HTLV-I infection 17/256 292/7206 0.0498727121382 ko04062 Chemokine signaling pathway 2/256 201/7206 0.0499531018995