ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	30/616	56/7206	3.66148000007e-18
ko04724	Glutamatergic synapse	50/616	152/7206	6.88282285564e-18
ko04721	Synaptic vesicle cycle	35/616	80/7206	2.40582260253e-17
ko04728	Dopaminergic synapse	50/616	185/7206	5.21998378924e-14
ko04727	GABAergic synapse	37/616	110/7206	7.06917425067e-14
ko05032	Morphine addiction	36/616	110/7206	4.0062399507e-13
ko04080	Neuroactive ligand-receptor interaction	80/616	423/7206	4.38812542285e-12
ko04723	Retrograde endocannabinoid signaling	45/616	175/7206	6.74502756788e-12
ko04713	Circadian entrainment	37/616	136/7206	9.1650296143e-11
ko04514	Cell adhesion molecules (CAMs)	33/616	130/7206	6.67221583624e-09
ko04725	Cholinergic synapse	37/616	160/7206	1.25441396778e-08
ko04024	cAMP signaling pathway	53/616	279/7206	1.87041266101e-08
ko04911	Insulin secretion	29/616	117/7206	9.8111652089e-08
ko05030	Cocaine addiction	21/616	73/7206	4.08964777179e-07
ko04726	Serotonergic synapse	29/616	137/7206	3.33827160182e-06
ko04744	Phototransduction	13/616	36/7206	4.18076585835e-06
ko04360	Axon guidance	41/616	233/7206	6.69935653045e-06
ko03040	Spliceosome	1/616	145/7206	6.07837551404e-05
ko05203	Viral carcinogenesis	7/616	277/7206	6.21817123905e-05
ko04261	Adrenergic signaling in cardiomyocytes	35/616	205/7206	6.27959094937e-05
ko05031	Amphetamine addiction	20/616	91/7206	6.33003136723e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/616	14/7206	6.4897450585e-05
ko04120	Ubiquitin mediated proteolysis	1/616	138/7206	8.80067582057e-05
ko04060	Cytokine-cytokine receptor interaction	4/616	191/7206	0.000327261804968
ko05164	Influenza A	3/616	167/7206	0.000386128127496
ko05014	Amyotrophic lateral sclerosis (ALS)	16/616	74/7206	0.000410397257993
ko05162	Measles	1/616	120/7206	0.00042123683985
ko04966	Collecting duct acid secretion	8/616	26/7206	0.00106117408421
ko04742	Taste transduction	13/616	61/7206	0.00161310468899
ko03013	RNA transport	4/616	166/7206	0.00179745817341
ko04141	Protein processing in endoplasmic reticulum	5/616	184/7206	0.0019276187145
ko05168	Herpes simplex infection	5/616	182/7206	0.00274912786564
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/616	182/7206	0.00274912786564
ko04621	NOD-like receptor signaling pathway	4/616	157/7206	0.00351304504048
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/616	59/7206	0.00363597133935
ko05322	Systemic lupus erythematosus	4/616	151/7206	0.00485757402476
ko05169	Epstein-Barr virus infection	7/616	206/7206	0.00499471912707
ko05205	Proteoglycans in cancer	11/616	271/7206	0.0052967484719
ko04010	MAPK signaling pathway	42/616	321/7206	0.00549705790613
ko01200	Carbon metabolism	3/616	128/7206	0.00630486040694
ko04140	Autophagy - animal	5/616	164/7206	0.00687991721992
ko04611	Platelet activation	5/616	163/7206	0.00688087147447
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/616	79/7206	0.00731577922698
ko04970	Salivary secretion	16/616	95/7206	0.00819802129592
ko04972	Pancreatic secretion	18/616	111/7206	0.00884141603176
ko04964	Proximal tubule bicarbonate reclamation	7/616	29/7206	0.00951483711208
ko04950	Maturity onset diabetes of the young	7/616	29/7206	0.00951483711208
ko04720	Long-term potentiation	16/616	99/7206	0.0107228834013
ko05418	Fluid shear stress and atherosclerosis	6/616	173/7206	0.0124865170401
ko03008	Ribosome biogenesis in eukaryotes	1/616	79/7206	0.0134832147463
ko04064	NF-kappa B signaling pathway	2/616	96/7206	0.0159775978392
ko00564	Glycerophospholipid metabolism	2/616	99/7206	0.0166085499035
ko05146	Amoebiasis	2/616	99/7206	0.0166085499035
ko04630	Jak-STAT signaling pathway	4/616	132/7206	0.0175813716177
ko00310	Lysine degradation	1/616	73/7206	0.0194237712419
ko04214	Apoptosis - fly	1/616	72/7206	0.0194248357103
ko05110	Vibrio cholerae infection	11/616	63/7206	0.020147468225
ko04730	Long-term depression	13/616	78/7206	0.0217443336087
ko04512	ECM-receptor interaction	13/616	79/7206	0.0226832687714
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/616	8/7206	0.0251201897954
ko05161	Hepatitis B	7/616	173/7206	0.0274655210798
ko04962	Vasopressin-regulated water reabsorption	10/616	58/7206	0.0292523870355
ko04340	Hedgehog signaling pathway	10/616	58/7206	0.0292523870355
ko05166	HTLV-I infection	15/616	292/7206	0.0321522417577
ko04146	Peroxisome	2/616	89/7206	0.0329644450177
ko04391	Hippo signaling pathway - fly	14/616	90/7206	0.0336678847484
ko05120	Epithelial cell signaling in Helicobacter pylori infection	14/616	92/7206	0.0356334795536
ko04540	Gap junction	18/616	128/7206	0.0359391568636
ko04910	Insulin signaling pathway	7/616	172/7206	0.036812931686
ko04974	Protein digestion and absorption	14/616	96/7206	0.0418225978912
ko04933	AGE-RAGE signaling pathway in diabetic complications	5/616	135/7206	0.0420478115709
ko04976	Bile secretion	12/616	80/7206	0.044546571791
ko04138	Autophagy - yeast	2/616	81/7206	0.0449985348286
ko05034	Alcoholism	29/616	238/7206	0.0451655406804
ko04137	Mitophagy - animal	2/616	82/7206	0.0451706175297
ko03018	RNA degradation	2/616	84/7206	0.0462496539199
ko04145	Phagosome	21/616	162/7206	0.0467435560993
ko04014	Ras signaling pathway	33/616	279/7206	0.0493920572458