ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 26/227 152/7206 9.17257899138e-13 ko04744 Phototransduction 13/227 36/7206 2.59990770462e-11 ko04727 GABAergic synapse 15/227 110/7206 1.54743700397e-06 ko05032 Morphine addiction 15/227 110/7206 1.54743700397e-06 ko04024 cAMP signaling pathway 25/227 279/7206 1.95569455853e-06 ko04072 Phospholipase D signaling pathway 20/227 197/7206 3.34424466799e-06 ko04723 Retrograde endocannabinoid signaling 18/227 175/7206 8.78007539064e-06 ko04713 Circadian entrainment 15/227 136/7206 2.19619585142e-05 ko04721 Synaptic vesicle cycle 11/227 80/7206 3.67062202363e-05 ko04725 Cholinergic synapse 16/227 160/7206 3.98639464612e-05 ko04728 Dopaminergic synapse 16/227 185/7206 0.000224971882998 ko05033 Nicotine addiction 8/227 56/7206 0.000329984507087 ko04062 Chemokine signaling pathway 16/227 201/7206 0.000572476089352 ko04261 Adrenergic signaling in cardiomyocytes 16/227 205/7206 0.00071027449232 ko05030 Cocaine addiction 8/227 73/7206 0.00197367600727 ko05203 Viral carcinogenesis 1/227 277/7206 0.00234905095927 ko04742 Taste transduction 7/227 61/7206 0.00287884858479 ko04911 Insulin secretion 10/227 117/7206 0.00369631446998 ko00562 Inositol phosphate metabolism 8/227 89/7206 0.00675105954934 ko04070 Phosphatidylinositol signaling system 9/227 112/7206 0.00859605305615 ko04080 Neuroactive ligand-receptor interaction 23/227 423/7206 0.00922926857908 ko04962 Vasopressin-regulated water reabsorption 6/227 58/7206 0.00943591369788 ko05231 Choline metabolism in cancer 10/227 134/7206 0.00951502009047 ko00513 Various types of N-glycan biosynthesis 5/227 42/7206 0.00976765726287 ko04923 Regulation of lipolysis in adipocytes 7/227 77/7206 0.0103944539932 ko04726 Serotonergic synapse 10/227 137/7206 0.0110299051908 ko05205 Proteoglycans in cancer 2/227 271/7206 0.0125963967548 ko04666 Fc gamma R-mediated phagocytosis 9/227 122/7206 0.0145799756897 ko04144 Endocytosis 19/227 342/7206 0.0158472501366 ko04014 Ras signaling pathway 16/227 279/7206 0.0207612089389 ko04915 Estrogen signaling pathway 9/227 131/7206 0.0222019454968 ko05414 Dilated cardiomyopathy 8/227 112/7206 0.0246482549798 ko04022 cGMP-PKG signaling pathway 13/227 216/7206 0.0260345034922 ko04371 Apelin signaling pathway 11/227 177/7206 0.0270235437384 ko04020 Calcium signaling pathway 15/227 265/7206 0.0286676125585 ko04060 Cytokine-cytokine receptor interaction 1/227 191/7206 0.0323107365852 ko04720 Long-term potentiation 7/227 99/7206 0.0361770661082 ko04740 Olfactory transduction 6/227 80/7206 0.0397720223507 ko00515 Mannose type O-glycan biosynthesis 3/227 25/7206 0.0425945811124 ko05213 Endometrial cancer 5/227 62/7206 0.0449631333299 ko01521 EGFR tyrosine kinase inhibitor resistance 7/227 106/7206 0.0493839895111