ko pathway ratio_in_study ratio_in_pop p_value ko01200 Carbon metabolism 22/147 128/7206 6.40657697766e-15 ko00020 Citrate cycle (TCA cycle) 11/147 35/7206 4.79568711234e-11 ko00010 Glycolysis / Gluconeogenesis 14/147 74/7206 1.850837888e-10 ko05410 Hypertrophic cardiomyopathy (HCM) 14/147 100/7206 1.13881847463e-08 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 12/147 79/7206 5.24533974485e-08 ko04260 Cardiac muscle contraction 13/147 98/7206 7.54675723346e-08 ko00620 Pyruvate metabolism 9/147 46/7206 2.77299252531e-07 ko05414 Dilated cardiomyopathy 13/147 112/7206 3.73485559782e-07 ko04921 Oxytocin signaling pathway 17/147 209/7206 1.02081879303e-06 ko01230 Biosynthesis of amino acids 10/147 85/7206 7.77030181855e-06 ko05016 Huntington's disease 15/147 215/7206 2.93300404031e-05 ko00030 Pentose phosphate pathway 6/147 32/7206 3.80564015022e-05 ko00190 Oxidative phosphorylation 11/147 127/7206 5.12625977941e-05 ko00680 Methane metabolism 6/147 34/7206 5.46127580271e-05 ko00500 Starch and sucrose metabolism 6/147 35/7206 6.48134051072e-05 ko05012 Parkinson's disease 12/147 155/7206 7.0338712452e-05 ko04020 Calcium signaling pathway 16/147 265/7206 9.12069095273e-05 ko00710 Carbon fixation in photosynthetic organisms 5/147 27/7206 0.000185444240518 ko05010 Alzheimer's disease 13/147 202/7206 0.000229650636037 ko04371 Apelin signaling pathway 11/147 177/7206 0.000940111219921 ko00250 Alanine, aspartate and glutamate metabolism 5/147 38/7206 0.000962727077078 ko04922 Glucagon signaling pathway 9/147 128/7206 0.00116111234902 ko04022 cGMP-PKG signaling pathway 12/147 216/7206 0.00147470870413 ko04261 Adrenergic signaling in cardiomyocytes 11/147 205/7206 0.00303831172681 ko04010 MAPK signaling pathway 15/147 321/7206 0.0033589574065 ko00052 Galactose metabolism 4/147 33/7206 0.00429450641908 ko04152 AMPK signaling pathway 9/147 161/7206 0.00551129681223 ko01210 2-Oxocarboxylic acid metabolism 3/147 20/7206 0.00735079956378 ko04510 Focal adhesion 11/147 240/7206 0.00976978152767 ko00051 Fructose and mannose metabolism 4/147 42/7206 0.0101997956916 ko00220 Arginine biosynthesis 3/147 24/7206 0.0122985956772 ko04964 Proximal tubule bicarbonate reclamation 3/147 29/7206 0.0206219225003 ko04910 Insulin signaling pathway 8/147 172/7206 0.0241196024784 ko05230 Central carbon metabolism in cancer 5/147 81/7206 0.0244907126774 ko05416 Viral myocarditis 4/147 55/7206 0.0253830833611 ko00640 Propanoate metabolism 3/147 34/7206 0.0313786035833 ko04932 Non-alcoholic fatty liver disease (NAFLD) 8/147 182/7206 0.0323347365526 ko04270 Vascular smooth muscle contraction 7/147 154/7206 0.0377266629144 ko00300 Lysine biosynthesis 1/147 2/7206 0.0403859610397 ko00630 Glyoxylate and dicarboxylate metabolism 3/147 38/7206 0.0417220213658 ko00720 Carbon fixation pathways in prokaryotes 2/147 17/7206 0.0460129444135