ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	53/491	152/7206	6.67645064742e-25
ko05033	Nicotine addiction	28/491	56/7206	1.31212124763e-18
ko04728	Dopaminergic synapse	49/491	185/7206	2.41636487782e-17
ko04727	GABAergic synapse	37/491	110/7206	4.55948580912e-17
ko04723	Retrograde endocannabinoid signaling	47/491	175/7206	6.19366162723e-17
ko05032	Morphine addiction	36/491	110/7206	3.34961654666e-16
ko04721	Synaptic vesicle cycle	30/491	80/7206	1.53896982009e-15
ko04744	Phototransduction	19/491	36/7206	1.41380313025e-13
ko04080	Neuroactive ligand-receptor interaction	71/491	423/7206	3.53398342633e-13
ko04713	Circadian entrainment	34/491	136/7206	1.34883162598e-11
ko04725	Cholinergic synapse	37/491	160/7206	2.01375418553e-11
ko04024	cAMP signaling pathway	48/491	279/7206	1.31106493766e-09
ko04911	Insulin secretion	27/491	117/7206	1.19369734798e-08
ko04726	Serotonergic synapse	29/491	137/7206	2.7330320734e-08
ko05030	Cocaine addiction	20/491	73/7206	4.57046172292e-08
ko04514	Cell adhesion molecules (CAMs)	26/491	130/7206	4.73295607184e-07
ko04742	Taste transduction	16/491	61/7206	1.95086351897e-06
ko04261	Adrenergic signaling in cardiomyocytes	32/491	205/7206	7.67234548519e-06
ko05031	Amphetamine addiction	18/491	91/7206	3.26144755632e-05
ko04010	MAPK signaling pathway	41/491	321/7206	9.06593404538e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	15/491	74/7206	0.000109954321279
ko05203	Viral carcinogenesis	5/491	277/7206	0.000210141197664
ko04060	Cytokine-cytokine receptor interaction	2/491	191/7206	0.000222844388694
ko04720	Long-term potentiation	17/491	99/7206	0.000329473417917
ko05322	Systemic lupus erythematosus	1/491	151/7206	0.000463276720579
ko03040	Spliceosome	1/491	145/7206	0.000679980728238
ko04740	Olfactory transduction	14/491	80/7206	0.000895732348715
ko05164	Influenza A	2/491	167/7206	0.000972024540874
ko04120	Ubiquitin mediated proteolysis	1/491	138/7206	0.000994361168232
ko03013	RNA transport	2/491	166/7206	0.00146116262622
ko04970	Salivary secretion	15/491	95/7206	0.00176855146938
ko05169	Epstein-Barr virus infection	4/491	206/7206	0.00277981641061
ko05162	Measles	1/491	120/7206	0.00312257577715
ko04062	Chemokine signaling pathway	25/491	201/7206	0.00393588576042
ko04110	Cell cycle	2/491	145/7206	0.00412311791861
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/491	59/7206	0.00598770569664
ko05205	Proteoglycans in cancer	8/491	271/7206	0.00664217607494
ko04540	Gap junction	17/491	128/7206	0.00702369726187
ko04260	Cardiac muscle contraction	14/491	98/7206	0.00723011672581
ko05034	Alcoholism	27/491	238/7206	0.00830134807832
ko04630	Jak-STAT signaling pathway	2/491	132/7206	0.00834481939754
ko04072	Phospholipase D signaling pathway	23/491	197/7206	0.00950885009929
ko04730	Long-term depression	12/491	78/7206	0.0100628430918
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/491	79/7206	0.0104550739086
ko04921	Oxytocin signaling pathway	24/491	209/7206	0.0112871867536
ko04972	Pancreatic secretion	15/491	111/7206	0.0114362957012
ko04360	Axon guidance	26/491	233/7206	0.0114836939882
ko01200	Carbon metabolism	2/491	128/7206	0.0119719358054
ko00564	Glycerophospholipid metabolism	1/491	99/7206	0.0142190366271
ko04140	Autophagy - animal	4/491	164/7206	0.0183348155623
ko04391	Hippo signaling pathway - fly	12/491	90/7206	0.0201199698487
ko04014	Ras signaling pathway	29/491	279/7206	0.0207224509861
ko04976	Bile secretion	11/491	80/7206	0.0224747809854
ko05168	Herpes simplex infection	5/491	182/7206	0.024351843398
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/491	182/7206	0.024351843398
ko05166	HTLV-I infection	11/491	292/7206	0.0324458384862
ko04621	NOD-like receptor signaling pathway	4/491	157/7206	0.0350649884599
ko05016	Huntington's disease	7/491	215/7206	0.0377709578934
ko04974	Protein digestion and absorption	12/491	96/7206	0.0380068385774
ko04071	Sphingolipid signaling pathway	18/491	162/7206	0.0384204370523
ko04971	Gastric acid secretion	12/491	98/7206	0.0413769801131
ko04745	Phototransduction - fly	6/491	38/7206	0.0416699018875
ko04964	Proximal tubule bicarbonate reclamation	5/491	29/7206	0.0438976181296
ko03018	RNA degradation	1/491	84/7206	0.0450496522362
ko04350	TGF-beta signaling pathway	2/491	103/7206	0.0469118836895
ko04066	HIF-1 signaling pathway	3/491	123/7206	0.0471930381823
ko04371	Apelin signaling pathway	19/491	177/7206	0.0475983388612