ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	140/852	423/7206	3.48603357712e-33
ko05033	Nicotine addiction	38/852	56/7206	7.12777276011e-23
ko04724	Glutamatergic synapse	64/852	152/7206	1.12936756901e-21
ko04721	Synaptic vesicle cycle	39/852	80/7206	2.68960965301e-16
ko04728	Dopaminergic synapse	62/852	185/7206	2.98058229136e-15
ko05032	Morphine addiction	44/852	110/7206	2.81679135564e-14
ko04727	GABAergic synapse	42/852	110/7206	7.18935384338e-13
ko04713	Circadian entrainment	47/852	136/7206	2.14683946357e-12
ko04723	Retrograde endocannabinoid signaling	53/852	175/7206	2.88857998849e-11
ko04725	Cholinergic synapse	49/852	160/7206	1.0648730674e-10
ko04024	cAMP signaling pathway	71/852	279/7206	1.37304204472e-10
ko04911	Insulin secretion	38/852	117/7206	2.19890011012e-09
ko05203	Viral carcinogenesis	8/852	277/7206	1.05271021933e-07
ko04742	Taste transduction	23/852	61/7206	1.59468214488e-07
ko04726	Serotonergic synapse	38/852	137/7206	2.81114247766e-07
ko03040	Spliceosome	1/852	145/7206	3.48493087484e-07
ko05030	Cocaine addiction	25/852	73/7206	4.04125683393e-07
ko05031	Amphetamine addiction	28/852	91/7206	1.01167303838e-06
ko04060	Cytokine-cytokine receptor interaction	4/852	191/7206	1.09436404349e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	24/852	74/7206	2.10872762211e-06
ko05164	Influenza A	3/852	167/7206	2.4097332039e-06
ko04261	Adrenergic signaling in cardiomyocytes	48/852	205/7206	2.52987825899e-06
ko04744	Phototransduction	15/852	36/7206	5.49508010339e-06
ko04514	Cell adhesion molecules (CAMs)	34/852	130/7206	5.88298399332e-06
ko05168	Herpes simplex infection	5/852	182/7206	1.28619442776e-05
ko04360	Axon guidance	50/852	233/7206	1.90138249933e-05
ko04970	Salivary secretion	26/852	95/7206	3.16518041926e-05
ko04010	MAPK signaling pathway	63/852	321/7206	3.99178419149e-05
ko04120	Ubiquitin mediated proteolysis	3/852	138/7206	4.9808592712e-05
ko03013	RNA transport	5/852	166/7206	7.67897909121e-05
ko04020	Calcium signaling pathway	53/852	265/7206	9.10831085525e-05
ko05322	Systemic lupus erythematosus	4/852	151/7206	9.70389658579e-05
ko04720	Long-term potentiation	25/852	99/7206	0.000204682655404
ko04621	NOD-like receptor signaling pathway	5/852	157/7206	0.000227443382445
ko04964	Proximal tubule bicarbonate reclamation	11/852	29/7206	0.00027211152261
ko04921	Oxytocin signaling pathway	43/852	209/7206	0.000280771731842
ko04966	Collecting duct acid secretion	10/852	26/7206	0.000453706068564
ko05162	Measles	3/852	120/7206	0.000479700803396
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/852	182/7206	0.000679534401955
ko04141	Protein processing in endoplasmic reticulum	8/852	184/7206	0.000691699141005
ko04924	Renin secretion	21/852	86/7206	0.0010525038484
ko03008	Ribosome biogenesis in eukaryotes	1/852	79/7206	0.00119237440581
ko04740	Olfactory transduction	20/852	80/7206	0.00125848866853
ko05205	Proteoglycans in cancer	16/852	271/7206	0.00143453952121
ko05166	HTLV-I infection	18/852	292/7206	0.00154483002185
ko04022	cGMP-PKG signaling pathway	41/852	216/7206	0.00179784476178
ko04540	Gap junction	27/852	128/7206	0.00219751353669
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/852	79/7206	0.00225629898353
ko04214	Apoptosis - fly	1/852	72/7206	0.00260357009065
ko01200	Carbon metabolism	5/852	128/7206	0.00328441211083
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/852	59/7206	0.00345978009579
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/852	14/7206	0.00348016287237
ko05161	Hepatitis B	9/852	173/7206	0.00402703026057
ko04730	Long-term depression	18/852	78/7206	0.00425265488632
ko04512	ECM-receptor interaction	18/852	79/7206	0.00475719304633
ko00561	Glycerolipid metabolism	1/852	63/7206	0.00545627334729
ko04640	Hematopoietic cell lineage	1/852	64/7206	0.00551082590708
ko05169	Epstein-Barr virus infection	12/852	206/7206	0.00581691062172
ko04974	Protein digestion and absorption	21/852	96/7206	0.00590559540842
ko04217	Necroptosis	10/852	178/7206	0.006648454809
ko04976	Bile secretion	18/852	80/7206	0.00766952552076
ko04146	Peroxisome	3/852	89/7206	0.00783664263944
ko00310	Lysine degradation	2/852	73/7206	0.0100002495606
ko05140	Leishmaniasis	2/852	75/7206	0.0103613376195
ko04014	Ras signaling pathway	47/852	279/7206	0.0105184227711
ko05215	Prostate cancer	5/852	111/7206	0.0114604155075
ko04110	Cell cycle	8/852	145/7206	0.013388166483
ko04137	Mitophagy - animal	3/852	82/7206	0.0155220750207
ko03018	RNA degradation	3/852	84/7206	0.0158456384681
ko04064	NF-kappa B signaling pathway	4/852	96/7206	0.0159617910858
ko00240	Pyrimidine metabolism	5/852	110/7206	0.0160423142626
ko04972	Pancreatic secretion	22/852	111/7206	0.0164350826058
ko04260	Cardiac muscle contraction	20/852	98/7206	0.0166164512978
ko04971	Gastric acid secretion	20/852	98/7206	0.0166164512978
ko05110	Vibrio cholerae infection	14/852	63/7206	0.0169606383123
ko00590	Arachidonic acid metabolism	1/852	52/7206	0.017530929075
ko00280	Valine, leucine and isoleucine degradation	1/852	54/7206	0.0177845587669
ko00480	Glutathione metabolism	1/852	55/7206	0.0183393252445
ko04611	Platelet activation	10/852	163/7206	0.0194803638528
ko04140	Autophagy - animal	10/852	164/7206	0.0195291773339
ko04630	Jak-STAT signaling pathway	7/852	132/7206	0.0195684219179
ko04978	Mineral absorption	10/852	40/7206	0.0220392091429
ko00380	Tryptophan metabolism	1/852	50/7206	0.0258646803909
ko04657	IL-17 signaling pathway	4/852	87/7206	0.0299927739921
ko04930	Type II diabetes mellitus	12/852	54/7206	0.0305712055294
ko04612	Antigen processing and presentation	3/852	77/7206	0.0310103947532
ko04925	Aldosterone synthesis and secretion	20/852	105/7206	0.0312711076727
ko04218	Cellular senescence	12/852	177/7206	0.0335425447806
ko04145	Phagosome	28/852	162/7206	0.0358050334426
ko03420	Nucleotide excision repair	1/852	46/7206	0.0377156658705
ko00260	Glycine, serine and threonine metabolism	1/852	48/7206	0.0393032706581
ko05219	Bladder cancer	1/852	48/7206	0.0393032706581
ko05016	Huntington's disease	16/852	215/7206	0.0415765786038
ko04391	Hippo signaling pathway - fly	17/852	90/7206	0.0469505197876
ko01521	EGFR tyrosine kinase inhibitor resistance	6/852	106/7206	0.0480175518074
ko04150	mTOR signaling pathway	13/852	184/7206	0.0481959379237