ko pathway ratio_in_study ratio_in_pop p_value ko04972 Pancreatic secretion 23/270 111/7206 1.17974391503e-11 ko04974 Protein digestion and absorption 21/270 96/7206 3.22420913725e-11 ko04976 Bile secretion 18/270 80/7206 5.29479876705e-10 ko04080 Neuroactive ligand-receptor interaction 40/270 423/7206 3.7921143483e-08 ko04975 Fat digestion and absorption 10/270 35/7206 3.69924914259e-07 ko04978 Mineral absorption 10/270 40/7206 1.44657258412e-06 ko04977 Vitamin digestion and absorption 7/270 22/7206 1.00860164028e-05 ko04614 Renin-angiotensin system 6/270 18/7206 3.32207924147e-05 ko02010 ABC transporters 8/270 39/7206 7.8339076533e-05 ko00591 Linoleic acid metabolism 6/270 22/7206 0.00011763153634 ko00983 Drug metabolism - other enzymes 8/270 42/7206 0.000136314913517 ko04610 Complement and coagulation cascades 11/270 79/7206 0.000156266263785 ko04971 Gastric acid secretion 12/270 98/7206 0.000274431152143 ko04924 Renin secretion 11/270 86/7206 0.000335381917354 ko00380 Tryptophan metabolism 8/270 50/7206 0.000478241437275 ko04970 Salivary secretion 11/270 95/7206 0.00079461706958 ko00830 Retinol metabolism 7/270 42/7206 0.000839130137597 ko04020 Calcium signaling pathway 21/270 265/7206 0.00129627339442 ko04742 Taste transduction 8/270 61/7206 0.0018381653745 ko05166 HTLV-I infection 2/270 292/7206 0.00227656391092 ko04730 Long-term depression 9/270 78/7206 0.00241131012779 ko04540 Gap junction 12/270 128/7206 0.00296039743303 ko00590 Arachidonic acid metabolism 7/270 52/7206 0.00302542983972 ko00140 Steroid hormone biosynthesis 6/270 41/7206 0.00390107954507 ko04964 Proximal tubule bicarbonate reclamation 5/270 29/7206 0.00403585305106 ko04713 Circadian entrainment 12/270 136/7206 0.00485771837538 ko05016 Huntington's disease 1/270 215/7206 0.00513415427946 ko00230 Purine metabolism 15/270 194/7206 0.00659174747906 ko05200 Pathways in cancer 8/270 492/7206 0.00664280297107 ko05010 Alzheimer's disease 1/270 202/7206 0.00729897188806 ko04724 Glutamatergic synapse 13/270 152/7206 0.00731353311579 ko04144 Endocytosis 4/270 342/7206 0.00772854314311 ko04921 Oxytocin signaling pathway 16/270 209/7206 0.00795437390388 ko00053 Ascorbate and aldarate metabolism 4/270 22/7206 0.0082704829391 ko00260 Glycine, serine and threonine metabolism 6/270 48/7206 0.00856158175403 ko04725 Cholinergic synapse 13/270 160/7206 0.00895473062956 ko00340 Histidine metabolism 4/270 25/7206 0.0130997034441 ko05203 Viral carcinogenesis 3/270 277/7206 0.014055653554 ko04270 Vascular smooth muscle contraction 12/270 154/7206 0.0152849477457 ko05033 Nicotine addiction 6/270 56/7206 0.0176837022162 ko04726 Serotonergic synapse 11/270 137/7206 0.0186184906913 ko04973 Carbohydrate digestion and absorption 5/270 42/7206 0.0194947452294 ko04727 GABAergic synapse 9/270 110/7206 0.0218436804507 ko05032 Morphine addiction 9/270 110/7206 0.0218436804507 ko05224 Breast cancer 1/270 174/7206 0.0229551012603 ko00592 alpha-Linolenic acid metabolism 3/270 19/7206 0.0323238168844 ko05204 Chemical carcinogenesis 5/270 48/7206 0.0327755951533 ko00680 Methane metabolism 4/270 34/7206 0.0369825174739 ko00860 Porphyrin and chlorophyll metabolism 4/270 34/7206 0.0369825174739 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/270 1/7206 0.0374687760199 ko04151 PI3K-Akt signaling pathway 7/270 390/7206 0.0383016520043 ko04723 Retrograde endocannabinoid signaling 12/270 175/7206 0.0403608141971 ko00100 Steroid biosynthesis 3/270 21/7206 0.0420085869735 ko04911 Insulin secretion 9/270 117/7206 0.0421073216526 ko04750 Inflammatory mediator regulation of TRP channels 9/270 122/7206 0.0482019429257 ko00982 Drug metabolism - cytochrome P450 4/270 37/7206 0.0483119984767 ko04150 mTOR signaling pathway 2/270 184/7206 0.0489653547612