ko pathway ratio_in_study ratio_in_pop p_value ko04010 MAPK signaling pathway 17/116 321/7206 1.28694480165e-05 ko04925 Aldosterone synthesis and secretion 9/116 105/7206 4.38189701004e-05 ko04912 GnRH signaling pathway 9/116 122/7206 0.000141549929488 ko04211 Longevity regulating pathway 9/116 123/7206 0.000150688803987 ko04923 Regulation of lipolysis in adipocytes 7/116 77/7206 0.00022160367821 ko04914 Progesterone-mediated oocyte maturation 8/116 104/7206 0.000251959143496 ko04144 Endocytosis 15/116 342/7206 0.000356934964312 ko05032 Morphine addiction 8/116 110/7206 0.000369953593242 ko04913 Ovarian steroidogenesis 6/116 63/7206 0.000491859432527 ko04072 Phospholipase D signaling pathway 10/116 197/7206 0.00122095702276 ko04713 Circadian entrainment 8/116 136/7206 0.00150322793206 ko04024 cAMP signaling pathway 12/116 279/7206 0.00169002460498 ko04727 GABAergic synapse 7/116 110/7206 0.00189686215961 ko04213 Longevity regulating pathway - multiple species 6/116 86/7206 0.00252301719176 ko04911 Insulin secretion 7/116 117/7206 0.00269614083556 ko04724 Glutamatergic synapse 8/116 152/7206 0.00302635214691 ko04020 Calcium signaling pathway 11/116 265/7206 0.00347125576183 ko01522 Endocrine resistance 7/116 124/7206 0.00373252417006 ko04725 Cholinergic synapse 8/116 160/7206 0.00414175762769 ko04540 Gap junction 7/116 128/7206 0.00444724745839 ko04261 Adrenergic signaling in cardiomyocytes 9/116 205/7206 0.00563578346275 ko05030 Cocaine addiction 5/116 73/7206 0.00623681189691 ko00515 Mannose type O-glycan biosynthesis 3/116 25/7206 0.00722168491397 ko04022 cGMP-PKG signaling pathway 9/116 216/7206 0.00786281134148 ko05414 Dilated cardiomyopathy 6/116 112/7206 0.00917064182527 ko04930 Type II diabetes mellitus 4/116 54/7206 0.0108602490012 ko04918 Thyroid hormone synthesis 5/116 86/7206 0.0122693443036 ko00230 Purine metabolism 8/116 194/7206 0.0127374790611 ko05031 Amphetamine addiction 5/116 91/7206 0.0153832720433 ko04970 Salivary secretion 5/116 95/7206 0.0182257580843 ko05110 Vibrio cholerae infection 4/116 63/7206 0.0183269701167 ko04915 Estrogen signaling pathway 6/116 131/7206 0.0187616042856 ko04910 Insulin signaling pathway 7/116 172/7206 0.0206706100243 ko04723 Retrograde endocannabinoid signaling 7/116 175/7206 0.0224857835639 ko04371 Apelin signaling pathway 7/116 177/7206 0.0237557179332 ko04114 Oocyte meiosis 6/116 139/7206 0.0243303622062 ko04972 Pancreatic secretion 5/116 111/7206 0.0329919217368 ko04070 Phosphatidylinositol signaling system 5/116 112/7206 0.0341050656577 ko04270 Vascular smooth muscle contraction 6/116 154/7206 0.0375552891405 ko04976 Bile secretion 4/116 80/7206 0.0395977640348 ko04624 Toll and Imd signaling pathway 3/116 49/7206 0.0438478035634 ko04668 TNF signaling pathway 5/116 120/7206 0.043851685905 ko04750 Inflammatory mediator regulation of TRP channels 5/116 122/7206 0.046524828843 ko04977 Vitamin digestion and absorption 2/116 22/7206 0.0481303080992 ko04140 Autophagy - animal 6/116 164/7206 0.0485293821866