ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	106/596	423/7206	2.44148644043e-27
ko04724	Glutamatergic synapse	59/596	152/7206	5.55516806008e-26
ko05033	Nicotine addiction	35/596	56/7206	1.30422957622e-24
ko05032	Morphine addiction	47/596	110/7206	5.36654766802e-23
ko04713	Circadian entrainment	51/596	136/7206	9.10544106286e-22
ko04727	GABAergic synapse	45/596	110/7206	3.9835974822e-21
ko04723	Retrograde endocannabinoid signaling	56/596	175/7206	5.73766002886e-20
ko04728	Dopaminergic synapse	57/596	185/7206	2.02150153245e-19
ko04744	Phototransduction	23/596	36/7206	7.03133325599e-17
ko04721	Synaptic vesicle cycle	31/596	80/7206	3.91190672854e-14
ko04024	cAMP signaling pathway	63/596	279/7206	4.77027826992e-14
ko04921	Oxytocin signaling pathway	52/596	209/7206	1.55864858321e-13
ko04725	Cholinergic synapse	44/596	160/7206	2.96822117285e-13
ko04911	Insulin secretion	36/596	117/7206	1.19780684689e-12
ko04726	Serotonergic synapse	38/596	137/7206	9.85041910176e-12
ko04261	Adrenergic signaling in cardiomyocytes	47/596	205/7206	5.46400606166e-11
ko05031	Amphetamine addiction	28/596	91/7206	4.05409608137e-10
ko04740	Olfactory transduction	24/596	80/7206	1.29042725099e-08
ko04970	Salivary secretion	26/596	95/7206	2.67616213953e-08
ko04742	Taste transduction	20/596	61/7206	4.03374110005e-08
ko05030	Cocaine addiction	22/596	73/7206	4.78253128658e-08
ko04720	Long-term potentiation	25/596	99/7206	2.75347530085e-07
ko04020	Calcium signaling pathway	46/596	265/7206	1.03325864159e-06
ko04010	MAPK signaling pathway	51/596	321/7206	3.81595678044e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	19/596	74/7206	5.74601822043e-06
ko05164	Influenza A	1/596	167/7206	1.24462383849e-05
ko04924	Renin secretion	20/596	86/7206	1.64296476804e-05
ko04060	Cytokine-cytokine receptor interaction	2/596	191/7206	2.28416699686e-05
ko04925	Aldosterone synthesis and secretion	22/596	105/7206	3.61602201405e-05
ko04022	cGMP-PKG signaling pathway	36/596	216/7206	4.23129835039e-05
ko04730	Long-term depression	18/596	78/7206	4.83206631029e-05
ko05322	Systemic lupus erythematosus	1/596	151/7206	6.40392677483e-05
ko04972	Pancreatic secretion	22/596	111/7206	8.77577402881e-05
ko03040	Spliceosome	1/596	145/7206	9.17257519986e-05
ko04260	Cardiac muscle contraction	20/596	98/7206	0.000119499020546
ko04120	Ubiquitin mediated proteolysis	1/596	138/7206	0.000132608850572
ko05203	Viral carcinogenesis	8/596	277/7206	0.000320255313408
ko04540	Gap junction	23/596	128/7206	0.000468565062948
ko04745	Phototransduction - fly	10/596	38/7206	0.000780959213457
ko05414	Dilated cardiomyopathy	20/596	112/7206	0.000818016333828
ko05168	Herpes simplex infection	4/596	182/7206	0.000927341245828
ko04150	mTOR signaling pathway	4/596	184/7206	0.000948774824046
ko04510	Focal adhesion	7/596	240/7206	0.00112481355246
ko04971	Gastric acid secretion	18/596	98/7206	0.0011780084243
ko05215	Prostate cancer	1/596	111/7206	0.00138784408515
ko03013	RNA transport	4/596	166/7206	0.00253675726406
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/596	59/7206	0.00276774825583
ko05169	Epstein-Barr virus infection	6/596	206/7206	0.0028155084716
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/596	79/7206	0.00284393300778
ko04630	Jak-STAT signaling pathway	3/596	132/7206	0.00636830241678
ko05205	Proteoglycans in cancer	11/596	271/7206	0.0091838695903
ko05034	Alcoholism	31/596	238/7206	0.0112944777624
ko04062	Chemokine signaling pathway	27/596	201/7206	0.0126885131476
ko04626	Plant-pathogen interaction	5/596	18/7206	0.0131576363013
ko04514	Cell adhesion molecules (CAMs)	19/596	130/7206	0.014480177102
ko05161	Hepatitis B	6/596	173/7206	0.0167942341477
ko04966	Collecting duct acid secretion	6/596	26/7206	0.0171711947124
ko04621	NOD-like receptor signaling pathway	5/596	157/7206	0.0177996076947
ko01524	Platinum drug resistance	1/596	76/7206	0.0196474947111
ko05130	Pathogenic Escherichia coli infection	1/596	77/7206	0.0198749163764
ko04612	Antigen processing and presentation	1/596	77/7206	0.0198749163764
ko03008	Ribosome biogenesis in eukaryotes	1/596	79/7206	0.0207671548668
ko04141	Protein processing in endoplasmic reticulum	7/596	184/7206	0.0209765127445
ko04976	Bile secretion	13/596	80/7206	0.0214344436441
ko04810	Regulation of actin cytoskeleton	12/596	264/7206	0.0224196567945
ko05016	Huntington's disease	9/596	215/7206	0.0233755440817
ko05410	Hypertrophic cardiomyopathy (HCM)	15/596	100/7206	0.0254546784518
ko04210	Apoptosis	7/596	180/7206	0.027663418232
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/596	182/7206	0.0279649457467
ko04964	Proximal tubule bicarbonate reclamation	6/596	29/7206	0.0287061914934
ko04214	Apoptosis - fly	1/596	72/7206	0.0288333634015
ko05166	HTLV-I infection	14/596	292/7206	0.0292212531047
ko04750	Inflammatory mediator regulation of TRP channels	17/596	122/7206	0.0298161669311
ko04146	Peroxisome	2/596	89/7206	0.0321967518424
ko05222	Small cell lung cancer	2/596	89/7206	0.0321967518424
ko04072	Phospholipase D signaling pathway	25/596	197/7206	0.034376519672
ko04014	Ras signaling pathway	33/596	279/7206	0.0344862715363
ko04070	Phosphatidylinositol signaling system	16/596	112/7206	0.0352215676166
ko04360	Axon guidance	28/596	233/7206	0.0396573198244
ko03320	PPAR signaling pathway	1/596	69/7206	0.0433886988954
ko04978	Mineral absorption	7/596	40/7206	0.043408120837
ko04668	TNF signaling pathway	4/596	120/7206	0.0444526843601
ko05220	Chronic myeloid leukemia	2/596	85/7206	0.0455314425319
ko04350	TGF-beta signaling pathway	3/596	103/7206	0.045958863713
ko00230	Purine metabolism	24/596	194/7206	0.0460246052444