ko pathway ratio_in_study ratio_in_pop p_value ko05340 Primary immunodeficiency 13/152 30/7206 8.59013807709e-15 ko04060 Cytokine-cytokine receptor interaction 24/152 191/7206 9.95486045991e-13 ko04612 Antigen processing and presentation 14/152 77/7206 5.06592450441e-10 ko04650 Natural killer cell mediated cytotoxicity 15/152 97/7206 1.2732232412e-09 ko04659 Th17 cell differentiation 15/152 106/7206 4.53252901705e-09 ko04658 Th1 and Th2 cell differentiation 13/152 96/7206 8.74817068628e-08 ko04380 Osteoclast differentiation 15/152 134/7206 1.1507734595e-07 ko05321 Inflammatory bowel disease (IBD) 10/152 56/7206 2.00923513535e-07 ko05152 Tuberculosis 17/152 187/7206 3.39637505337e-07 ko05145 Toxoplasmosis 14/152 126/7206 3.41800741059e-07 ko05140 Leishmaniasis 11/152 75/7206 3.92993910533e-07 ko04064 NF-kappa B signaling pathway 11/152 96/7206 4.83742061443e-06 ko04640 Hematopoietic cell lineage 9/152 64/7206 6.67505935961e-06 ko05330 Allograft rejection 6/152 24/7206 7.84658815404e-06 ko04660 T cell receptor signaling pathway 12/152 124/7206 1.04761095886e-05 ko05310 Asthma 5/152 17/7206 1.97157108269e-05 ko04630 Jak-STAT signaling pathway 12/152 132/7206 1.98587127188e-05 ko05320 Autoimmune thyroid disease 6/152 29/7206 2.53797352855e-05 ko05168 Herpes simplex infection 14/152 182/7206 2.69661653696e-05 ko04145 Phagosome 13/152 162/7206 3.39178422843e-05 ko05164 Influenza A 13/152 167/7206 4.66913520102e-05 ko05150 Staphylococcus aureus infection 6/152 36/7206 9.21266788121e-05 ko04672 Intestinal immune network for IgA production 6/152 37/7206 0.00010806187794 ko05416 Viral myocarditis 7/152 55/7206 0.000140499714556 ko04664 Fc epsilon RI signaling pathway 8/152 77/7206 0.000200058145657 ko05162 Measles 10/152 120/7206 0.00020647346206 ko04062 Chemokine signaling pathway 13/152 201/7206 0.00030446980035 ko04217 Necroptosis 12/152 178/7206 0.000357557054359 ko04621 NOD-like receptor signaling pathway 11/152 157/7206 0.000455437974181 ko05332 Graft-versus-host disease 4/152 18/7206 0.000462390017706 ko04662 B cell receptor signaling pathway 8/152 88/7206 0.000502637677312 ko00590 Arachidonic acid metabolism 6/152 52/7206 0.000729488046144 ko04610 Complement and coagulation cascades 7/152 79/7206 0.00131636812926 ko04514 Cell adhesion molecules (CAMs) 9/152 130/7206 0.00163699564992 ko04611 Platelet activation 10/152 163/7206 0.00226274454661 ko05167 Kaposi's sarcoma-associated herpesvirus infection 11/152 191/7206 0.00227536767269 ko05133 Pertussis 7/152 87/7206 0.00230680169633 ko05144 Malaria 5/152 45/7206 0.00241974228599 ko05323 Rheumatoid arthritis 7/152 89/7206 0.00262663242306 ko04666 Fc gamma R-mediated phagocytosis 8/152 122/7206 0.00412616624781 ko04940 Type I diabetes mellitus 4/152 32/7206 0.00432107646984 ko04670 Leukocyte transendothelial migration 9/152 151/7206 0.00451306247853 ko04620 Toll-like receptor signaling pathway 7/152 100/7206 0.00503638334333 ko05169 Epstein-Barr virus infection 10/152 206/7206 0.011581954677 ko00511 Other glycan degradation 3/152 26/7206 0.0167678662798 ko03050 Proteasome 4/152 54/7206 0.0266286072939 ko05161 Hepatitis B 8/152 173/7206 0.0296041088397 ko00600 Sphingolipid metabolism 4/152 63/7206 0.0434367668968