ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	116/532	423/7206	4.12132037158e-39
ko05033	Nicotine addiction	39/532	56/7206	5.80023492563e-32
ko04724	Glutamatergic synapse	54/532	152/7206	4.32326720447e-24
ko04727	GABAergic synapse	38/532	110/7206	9.16120113011e-17
ko04723	Retrograde endocannabinoid signaling	48/532	175/7206	2.92165237526e-16
ko04713	Circadian entrainment	40/532	136/7206	7.49680969492e-15
ko04728	Dopaminergic synapse	47/532	185/7206	1.51838445689e-14
ko05032	Morphine addiction	35/532	110/7206	2.75674523504e-14
ko04721	Synaptic vesicle cycle	29/532	80/7206	1.06445386891e-13
ko04024	cAMP signaling pathway	58/532	279/7206	1.60157932884e-13
ko04725	Cholinergic synapse	36/532	160/7206	8.37389977139e-10
ko04742	Taste transduction	21/532	61/7206	8.64116807603e-10
ko04261	Adrenergic signaling in cardiomyocytes	41/532	205/7206	2.42646715413e-09
ko04726	Serotonergic synapse	32/532	137/7206	2.78594287087e-09
ko05030	Cocaine addiction	22/532	73/7206	5.96697355085e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	22/532	74/7206	7.91571390578e-09
ko04921	Oxytocin signaling pathway	40/532	209/7206	1.43761730569e-08
ko05031	Amphetamine addiction	24/532	91/7206	2.2664900228e-08
ko04020	Calcium signaling pathway	46/532	265/7206	2.90450915666e-08
ko04911	Insulin secretion	27/532	117/7206	6.4991650335e-08
ko04720	Long-term potentiation	23/532	99/7206	5.45773202491e-07
ko04010	MAPK signaling pathway	49/532	321/7206	8.87441714106e-07
ko04970	Salivary secretion	22/532	95/7206	1.02216630659e-06
ko04730	Long-term depression	18/532	78/7206	1.03788494077e-05
ko05164	Influenza A	1/532	167/7206	6.4841668803e-05
ko04060	Cytokine-cytokine receptor interaction	2/532	191/7206	0.00010646707772
ko04260	Cardiac muscle contraction	18/532	98/7206	0.000250304903708
ko03040	Spliceosome	1/532	145/7206	0.000306334835327
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/532	79/7206	0.000560392437836
ko05203	Viral carcinogenesis	7/532	277/7206	0.000604111450061
ko04972	Pancreatic secretion	19/532	111/7206	0.000622886541231
ko04964	Proximal tubule bicarbonate reclamation	8/532	29/7206	0.000895591453897
ko04540	Gap junction	20/532	128/7206	0.00160490066023
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/532	14/7206	0.00245943990168
ko04971	Gastric acid secretion	16/532	98/7206	0.00253603258296
ko05205	Proteoglycans in cancer	8/532	271/7206	0.00279732627328
ko04120	Ubiquitin mediated proteolysis	2/532	138/7206	0.00281426907114
ko04022	cGMP-PKG signaling pathway	28/532	216/7206	0.00326941534517
ko05168	Herpes simplex infection	4/532	182/7206	0.00367075344905
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/532	182/7206	0.00367075344905
ko04621	NOD-like receptor signaling pathway	3/532	157/7206	0.00478986675842
ko05414	Dilated cardiomyopathy	17/532	112/7206	0.00504549111956
ko01200	Carbon metabolism	2/532	128/7206	0.00576212506633
ko04350	TGF-beta signaling pathway	1/532	103/7206	0.00666313783003
ko05322	Systemic lupus erythematosus	3/532	151/7206	0.0066792144534
ko04072	Phospholipase D signaling pathway	25/532	197/7206	0.00786729419545
ko05169	Epstein-Barr virus infection	6/532	206/7206	0.00958429852685
ko04514	Cell adhesion molecules (CAMs)	18/532	130/7206	0.00968766734247
ko04550	Signaling pathways regulating pluripotency of stem cells	4/532	165/7206	0.00969040191075
ko04141	Protein processing in endoplasmic reticulum	5/532	184/7206	0.00970520328469
ko03013	RNA transport	4/532	166/7206	0.00977697033465
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/532	59/7206	0.0103498813544
ko04924	Renin secretion	13/532	86/7206	0.0112156872068
ko04976	Bile secretion	12/532	80/7206	0.0158147207178
ko04014	Ras signaling pathway	31/532	279/7206	0.0192591907223
ko03018	RNA degradation	1/532	84/7206	0.020066623513
ko04071	Sphingolipid signaling pathway	20/532	162/7206	0.0214236804337
ko04510	Focal adhesion	9/532	240/7206	0.0238030636905
ko04915	Estrogen signaling pathway	17/532	131/7206	0.0260271800865
ko03008	Ribosome biogenesis in eukaryotes	1/532	79/7206	0.0291188648846
ko04360	Axon guidance	26/532	233/7206	0.030093794144
ko05146	Amoebiasis	2/532	99/7206	0.032878572437
ko05034	Alcoholism	26/532	238/7206	0.0425340998514
ko01524	Platinum drug resistance	1/532	76/7206	0.0431809961196
ko04612	Antigen processing and presentation	1/532	77/7206	0.0439872909462
ko00910	Nitrogen metabolism	4/532	19/7206	0.0468232210541
ko05410	Hypertrophic cardiomyopathy (HCM)	13/532	100/7206	0.0499789692007