ko pathway ratio_in_study ratio_in_pop p_value ko04080 Neuroactive ligand-receptor interaction 76/317 423/7206 6.07489605891e-28 ko05033 Nicotine addiction 25/317 56/7206 7.74203311719e-20 ko04727 GABAergic synapse 26/317 110/7206 8.08151764319e-13 ko04723 Retrograde endocannabinoid signaling 31/317 175/7206 1.68401606918e-11 ko05032 Morphine addiction 23/317 110/7206 2.55034714869e-10 ko04728 Dopaminergic synapse 29/317 185/7206 1.60576119246e-09 ko04724 Glutamatergic synapse 26/317 152/7206 1.73016783385e-09 ko04742 Taste transduction 15/317 61/7206 3.60963811694e-08 ko04721 Synaptic vesicle cycle 17/317 80/7206 4.59516679751e-08 ko04713 Circadian entrainment 22/317 136/7206 9.16934285572e-08 ko04725 Cholinergic synapse 23/317 160/7206 4.25986333582e-07 ko04024 cAMP signaling pathway 31/317 279/7206 1.49087451521e-06 ko04726 Serotonergic synapse 20/317 137/7206 1.92651491168e-06 ko04730 Long-term depression 13/317 78/7206 3.0012449214e-05 ko04911 Insulin secretion 16/317 117/7206 4.76209480427e-05 ko05030 Cocaine addiction 12/317 73/7206 6.98772403012e-05 ko04921 Oxytocin signaling pathway 22/317 209/7206 0.000190300794988 ko04970 Salivary secretion 13/317 95/7206 0.000242056004727 ko04010 MAPK signaling pathway 28/317 321/7206 0.000430413347166 ko05203 Viral carcinogenesis 2/317 277/7206 0.000501713313443 ko05031 Amphetamine addiction 12/317 91/7206 0.000589532528097 ko04961 Endocrine and other factor-regulated calcium reabsorption 9/317 59/7206 0.00099061020717 ko05014 Amyotrophic lateral sclerosis (ALS) 10/317 74/7206 0.00138067446502 ko04964 Proximal tubule bicarbonate reclamation 6/317 29/7206 0.00139109047201 ko04261 Adrenergic signaling in cardiomyocytes 19/317 205/7206 0.0025636742745 ko04972 Pancreatic secretion 12/317 111/7206 0.00336122461752 ko04060 Cytokine-cytokine receptor interaction 1/317 191/7206 0.00344628291327 ko04020 Calcium signaling pathway 22/317 265/7206 0.00347038571935 ko04260 Cardiac muscle contraction 11/317 98/7206 0.00367219737619 ko04971 Gastric acid secretion 11/317 98/7206 0.00367219737619 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/317 182/7206 0.00501685938625 ko00910 Nitrogen metabolism 4/317 19/7206 0.00842936706411 ko04720 Long-term potentiation 10/317 99/7206 0.0114003729284 ko05200 Pathways in cancer 11/317 492/7206 0.0119660620222 ko04540 Gap junction 12/317 128/7206 0.0134106671942 ko05205 Proteoglycans in cancer 4/317 271/7206 0.0143893614064 ko05152 Tuberculosis 2/317 187/7206 0.0176966907016 ko00604 Glycosphingolipid biosynthesis - ganglio series 3/317 14/7206 0.0213908896432 ko03040 Spliceosome 1/317 145/7206 0.0219344395221 ko04976 Bile secretion 8/317 80/7206 0.0237662799936 ko05168 Herpes simplex infection 2/317 182/7206 0.0255449846453 ko00533 Glycosaminoglycan biosynthesis - keratan sulfate 3/317 15/7206 0.0258858721543 ko04141 Protein processing in endoplasmic reticulum 2/317 184/7206 0.0260844264472 ko04960 Aldosterone-regulated sodium reabsorption 5/317 41/7206 0.0326761609771 ko04072 Phospholipase D signaling pathway 15/317 197/7206 0.0333568499053 ko03013 RNA transport 2/317 166/7206 0.0348247058423 ko04022 cGMP-PKG signaling pathway 16/317 216/7206 0.0406294057939 ko05166 HTLV-I infection 6/317 292/7206 0.0414434602914 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/317 1/7206 0.0439911185125 ko04066 HIF-1 signaling pathway 1/317 123/7206 0.0446431771793 ko05145 Toxoplasmosis 1/317 126/7206 0.0451937240205 ko01200 Carbon metabolism 1/317 128/7206 0.0459544918934