ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	24/392	56/7206	1.97809315617e-16
ko04724	Glutamatergic synapse	33/392	152/7206	3.55261539273e-12
ko04728	Dopaminergic synapse	36/392	185/7206	1.08723430568e-11
ko04080	Neuroactive ligand-receptor interaction	57/392	423/7206	1.00570789108e-10
ko04727	GABAergic synapse	26/392	110/7206	1.02636984325e-10
ko04721	Synaptic vesicle cycle	22/392	80/7206	1.24597946248e-10
ko04360	Axon guidance	37/392	233/7206	2.46003742748e-09
ko05032	Morphine addiction	24/392	110/7206	3.12951463806e-09
ko04723	Retrograde endocannabinoid signaling	31/392	175/7206	3.56047980762e-09
ko04024	cAMP signaling pathway	40/392	279/7206	1.1306498944e-08
ko04713	Circadian entrainment	24/392	136/7206	2.37388482533e-07
ko05030	Cocaine addiction	15/392	73/7206	6.59438971824e-06
ko04725	Cholinergic synapse	23/392	160/7206	1.58714284355e-05
ko04514	Cell adhesion molecules (CAMs)	20/392	130/7206	2.08383912094e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	14/392	74/7206	3.59167667212e-05
ko04911	Insulin secretion	18/392	117/7206	5.38715534485e-05
ko05031	Amphetamine addiction	14/392	91/7206	0.000361185561053
ko04921	Oxytocin signaling pathway	24/392	209/7206	0.000484762790835
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/392	14/7206	0.000617633684051
ko04261	Adrenergic signaling in cardiomyocytes	23/392	205/7206	0.000831159071685
ko05203	Viral carcinogenesis	4/392	277/7206	0.00102385855286
ko04072	Phospholipase D signaling pathway	22/392	197/7206	0.00116567232343
ko04010	MAPK signaling pathway	31/392	321/7206	0.00152193022972
ko03013	RNA transport	1/392	166/7206	0.00153618516365
ko04060	Cytokine-cytokine receptor interaction	2/392	191/7206	0.00305660458974
ko04964	Proximal tubule bicarbonate reclamation	6/392	29/7206	0.00407023810664
ko04970	Salivary secretion	12/392	95/7206	0.00514644708046
ko04742	Taste transduction	9/392	61/7206	0.00532496294808
ko05205	Proteoglycans in cancer	5/392	271/7206	0.00567469831105
ko04217	Necroptosis	2/392	178/7206	0.00635904570229
ko04015	Rap1 signaling pathway	26/392	278/7206	0.00641467228845
ko04071	Sphingolipid signaling pathway	17/392	162/7206	0.00789014423362
ko01200	Carbon metabolism	1/392	128/7206	0.0100658931336
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	10/392	79/7206	0.010100149085
ko04726	Serotonergic synapse	15/392	137/7206	0.0112398259499
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	5/392	26/7206	0.0118371211747
ko04621	NOD-like receptor signaling pathway	2/392	157/7206	0.0122711662176
ko05322	Systemic lupus erythematosus	2/392	151/7206	0.0173583357842
ko04972	Pancreatic secretion	12/392	111/7206	0.0189771191189
ko04260	Cardiac muscle contraction	11/392	98/7206	0.0209490733753
ko05210	Colorectal cancer	10/392	86/7206	0.0256651633674
ko04915	Estrogen signaling pathway	13/392	131/7206	0.0308117229541
ko04120	Ubiquitin mediated proteolysis	2/392	138/7206	0.0346919458872
ko04962	Vasopressin-regulated water reabsorption	7/392	58/7206	0.0367216963241
ko04730	Long-term depression	9/392	78/7206	0.0374159310981
ko04961	Endocrine and other factor-regulated calcium reabsorption	7/392	59/7206	0.0398007665863
ko04976	Bile secretion	9/392	80/7206	0.040012562859
ko02024	Quorum sensing	3/392	15/7206	0.0446207121892
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	3/392	15/7206	0.0446207121892
ko05016	Huntington's disease	5/392	215/7206	0.0450523767333
ko05168	Herpes simplex infection	4/392	182/7206	0.0467607555104
ko04141	Protein processing in endoplasmic reticulum	4/392	184/7206	0.046875107159
ko04144	Endocytosis	27/392	342/7206	0.0494843590002