ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 36/270 79/7206 4.21799479246e-31 ko04975 Fat digestion and absorption 16/270 35/7206 2.08257965283e-14 ko04950 Maturity onset diabetes of the young 12/270 29/7206 1.7662824753e-10 ko04974 Protein digestion and absorption 20/270 96/7206 2.46744361954e-10 ko04977 Vitamin digestion and absorption 10/270 22/7206 2.00876869486e-09 ko05150 Staphylococcus aureus infection 11/270 36/7206 4.35514385343e-08 ko00260 Glycine, serine and threonine metabolism 12/270 48/7206 1.2526333115e-07 ko04978 Mineral absorption 11/270 40/7206 1.46598279692e-07 ko00983 Drug metabolism - other enzymes 11/270 42/7206 2.53890739191e-07 ko04976 Bile secretion 14/270 80/7206 1.25669980582e-06 ko03320 PPAR signaling pathway 11/270 69/7206 4.39675662522e-05 ko00591 Linoleic acid metabolism 6/270 22/7206 0.00011763153634 ko05166 HTLV-I infection 1/270 292/7206 0.000233577162981 ko04972 Pancreatic secretion 13/270 111/7206 0.000240946160077 ko01200 Carbon metabolism 14/270 128/7206 0.000288772080534 ko00270 Cysteine and methionine metabolism 8/270 47/7206 0.000308732238131 ko00040 Pentose and glucuronate interconversions 6/270 26/7206 0.00031987689599 ko04614 Renin-angiotensin system 5/270 18/7206 0.000408009354105 ko00630 Glyoxylate and dicarboxylate metabolism 7/270 38/7206 0.000446138535893 ko04146 Peroxisome 11/270 89/7206 0.000453279656001 ko05200 Pathways in cancer 6/270 492/7206 0.000816867129928 ko04973 Carbohydrate digestion and absorption 7/270 42/7206 0.000839130137597 ko04360 Axon guidance 1/270 233/7206 0.0023526317868 ko00590 Arachidonic acid metabolism 7/270 52/7206 0.00302542983972 ko04010 MAPK signaling pathway 3/270 321/7206 0.00369082219764 ko00140 Steroid hormone biosynthesis 6/270 41/7206 0.00390107954507 ko04964 Proximal tubule bicarbonate reclamation 5/270 29/7206 0.00403585305106 ko00480 Glutathione metabolism 7/270 55/7206 0.00417203654967 ko01230 Biosynthesis of amino acids 9/270 85/7206 0.00433727403988 ko00830 Retinol metabolism 6/270 42/7206 0.00441140444625 ko05133 Pertussis 9/270 87/7206 0.00506404914674 ko05016 Huntington's disease 1/270 215/7206 0.00513415427946 ko00620 Pyruvate metabolism 6/270 46/7206 0.00695413031517 ko05169 Epstein-Barr virus infection 1/270 206/7206 0.00760247748455 ko04144 Endocytosis 4/270 342/7206 0.00772854314311 ko00053 Ascorbate and aldarate metabolism 4/270 22/7206 0.0082704829391 ko05204 Chemical carcinogenesis 6/270 48/7206 0.00856158175403 ko04060 Cytokine-cytokine receptor interaction 1/270 191/7206 0.0105580552713 ko00982 Drug metabolism - cytochrome P450 5/270 37/7206 0.011616838216 ko00472 D-Arginine and D-ornithine metabolism 2/270 5/7206 0.0129768595976 ko00232 Caffeine metabolism 2/270 5/7206 0.0129768595976 ko00311 Penicillin and cephalosporin biosynthesis 2/270 5/7206 0.0129768595976 ko00250 Alanine, aspartate and glutamate metabolism 5/270 38/7206 0.012978382731 ko00340 Histidine metabolism 4/270 25/7206 0.0130997034441 ko05034 Alcoholism 2/270 238/7206 0.013277228088 ko00770 Pantothenate and CoA biosynthesis 3/270 14/7206 0.0139319184972 ko02010 ABC transporters 5/270 39/7206 0.0144438509394 ko04217 Necroptosis 1/270 178/7206 0.0151092127228 ko04150 mTOR signaling pathway 1/270 184/7206 0.0157885917974 ko04141 Protein processing in endoplasmic reticulum 1/270 184/7206 0.0157885917974 ko05020 Prion diseases 5/270 40/7206 0.0160164228516 ko00980 Metabolism of xenobiotics by cytochrome P450 5/270 40/7206 0.0160164228516 ko04080 Neuroactive ligand-receptor interaction 7/270 423/7206 0.0167342620767 ko04931 Insulin resistance 11/270 137/7206 0.0186184906913 ko00565 Ether lipid metabolism 5/270 42/7206 0.0194947452294 ko00010 Glycolysis / Gluconeogenesis 7/270 74/7206 0.0203210592643 ko04550 Signaling pathways regulating pluripotency of stem cells 1/270 165/7206 0.0217465635179 ko05161 Hepatitis B 1/270 173/7206 0.0226972420083 ko04216 Ferroptosis 5/270 44/7206 0.0234352837562 ko00561 Glycerolipid metabolism 6/270 63/7206 0.0298377745219 ko00592 alpha-Linolenic acid metabolism 3/270 19/7206 0.0323238168844 ko04072 Phospholipase D signaling pathway 2/270 197/7206 0.0351024104869 ko05010 Alzheimer's disease 2/270 202/7206 0.0358392892846 ko00680 Methane metabolism 4/270 34/7206 0.0369825174739 ko00860 Porphyrin and chlorophyll metabolism 4/270 34/7206 0.0369825174739 ko00020 Citrate cycle (TCA cycle) 4/270 35/7206 0.0405683899567 ko00500 Starch and sucrose metabolism 4/270 35/7206 0.0405683899567 ko00100 Steroid biosynthesis 3/270 21/7206 0.0420085869735 ko04920 Adipocytokine signaling pathway 7/270 89/7206 0.048750376196 ko04728 Dopaminergic synapse 2/270 185/7206 0.0489730089679