ko pathway ratio_in_study ratio_in_pop p_value ko04950 Maturity onset diabetes of the young 17/348 29/7206 8.81509965429e-16 ko04610 Complement and coagulation cascades 20/348 79/7206 5.38876878921e-10 ko04020 Calcium signaling pathway 1/348 265/7206 5.05918429729e-05 ko00260 Glycine, serine and threonine metabolism 10/348 48/7206 7.65782690466e-05 ko04512 ECM-receptor interaction 13/348 79/7206 9.04989849691e-05 ko05217 Basal cell carcinoma 11/348 68/7206 0.000365589631457 ko03410 Base excision repair 8/348 38/7206 0.000373162192616 ko04340 Hedgehog signaling pathway 10/348 58/7206 0.000397152006144 ko04612 Antigen processing and presentation 11/348 77/7206 0.00108029169222 ko04975 Fat digestion and absorption 7/348 35/7206 0.00120049403322 ko04550 Signaling pathways regulating pluripotency of stem cells 18/348 165/7206 0.001219420663 ko04977 Vitamin digestion and absorption 5/348 22/7206 0.00340174780204 ko05205 Proteoglycans in cancer 24/348 271/7206 0.00352031894276 ko00430 Taurine and hypotaurine metabolism 4/348 14/7206 0.00363785273721 ko05010 Alzheimer's disease 2/348 202/7206 0.00434567841467 ko04921 Oxytocin signaling pathway 2/348 209/7206 0.00453782192234 ko04270 Vascular smooth muscle contraction 1/348 154/7206 0.00704555877477 ko05012 Parkinson's disease 1/348 155/7206 0.00707077043193 ko04060 Cytokine-cytokine receptor interaction 2/348 191/7206 0.00902629996067 ko03030 DNA replication 6/348 38/7206 0.00904574989529 ko04330 Notch signaling pathway 8/348 62/7206 0.00942736329666 ko04144 Endocytosis 7/348 342/7206 0.00951955739265 ko04371 Apelin signaling pathway 2/348 177/7206 0.0124231815455 ko04932 Non-alcoholic fatty liver disease (NAFLD) 2/348 182/7206 0.0127015320577 ko04080 Neuroactive ligand-receptor interaction 10/348 423/7206 0.0134097429631 ko00460 Cyanoamino acid metabolism 3/348 11/7206 0.013789780517 ko00670 One carbon pool by folate 4/348 20/7206 0.0140052225047 ko04726 Serotonergic synapse 1/348 137/7206 0.0147877270344 ko04723 Retrograde endocannabinoid signaling 2/348 175/7206 0.0181963495098 ko04510 Focal adhesion 20/348 240/7206 0.0199113360715 ko01230 Biosynthesis of amino acids 9/348 85/7206 0.0208611638074 ko00472 D-Arginine and D-ornithine metabolism 2/348 5/7206 0.0211035157179 ko00311 Penicillin and cephalosporin biosynthesis 2/348 5/7206 0.0211035157179 ko03010 Ribosome 1/348 129/7206 0.0213801924637 ko04725 Cholinergic synapse 2/348 160/7206 0.0246753472019 ko04071 Sphingolipid signaling pathway 2/348 162/7206 0.0247478095739 ko04974 Protein digestion and absorption 10/348 96/7206 0.0253648723126 ko04072 Phospholipase D signaling pathway 3/348 197/7206 0.0264459760477 ko00330 Arginine and proline metabolism 7/348 61/7206 0.0267358531682 ko05150 Staphylococcus aureus infection 5/348 36/7206 0.0280722649251 ko05224 Breast cancer 15/348 174/7206 0.0290234474844 ko04024 cAMP signaling pathway 6/348 279/7206 0.0315091767868 ko04341 Hedgehog signaling pathway - fly 5/348 38/7206 0.0345788726453 ko04022 cGMP-PKG signaling pathway 4/348 216/7206 0.0350331640087 ko04621 NOD-like receptor signaling pathway 2/348 157/7206 0.0354813182719 ko04151 PI3K-Akt signaling pathway 28/348 390/7206 0.0376329818425 ko05222 Small cell lung cancer 9/348 89/7206 0.039134759821 ko05020 Prion diseases 5/348 40/7206 0.0419471983169 ko04070 Phosphatidylinositol signaling system 1/348 112/7206 0.04433017228