ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	61/606	152/7206	2.21883460251e-27
ko04080	Neuroactive ligand-receptor interaction	107/606	423/7206	2.45104980252e-27
ko05033	Nicotine addiction	36/606	56/7206	1.16125575748e-25
ko04727	GABAergic synapse	44/606	110/7206	6.27673462753e-20
ko05032	Morphine addiction	44/606	110/7206	6.27673462753e-20
ko04723	Retrograde endocannabinoid signaling	55/606	175/7206	7.04913653849e-19
ko04713	Circadian entrainment	45/606	136/7206	1.37098010411e-16
ko04024	cAMP signaling pathway	67/606	279/7206	6.00271801582e-16
ko04728	Dopaminergic synapse	51/606	185/7206	6.14067175241e-15
ko04020	Calcium signaling pathway	62/606	265/7206	2.94701803841e-14
ko04911	Insulin secretion	37/606	117/7206	3.73809665881e-13
ko04725	Cholinergic synapse	42/606	160/7206	9.88400050932e-12
ko04726	Serotonergic synapse	38/606	137/7206	1.63529932704e-11
ko04261	Adrenergic signaling in cardiomyocytes	48/606	205/7206	2.75398285121e-11
ko04720	Long-term potentiation	31/606	99/7206	4.24270706448e-11
ko04721	Synaptic vesicle cycle	26/606	80/7206	6.5165939981e-10
ko04921	Oxytocin signaling pathway	46/606	209/7206	6.61627783801e-10
ko04010	MAPK signaling pathway	61/606	321/7206	7.31425951229e-10
ko05031	Amphetamine addiction	27/606	91/7206	2.98060342811e-09
ko04742	Taste transduction	20/606	61/7206	5.33548900702e-08
ko04925	Aldosterone synthesis and secretion	27/606	105/7206	8.5997848393e-08
ko04970	Salivary secretion	24/606	95/7206	6.42331988201e-07
ko04022	cGMP-PKG signaling pathway	40/606	216/7206	1.32380496194e-06
ko04070	Phosphatidylinositol signaling system	25/606	112/7206	4.39628406394e-06
ko04072	Phospholipase D signaling pathway	36/606	197/7206	6.2801490689e-06
ko04972	Pancreatic secretion	24/606	111/7206	1.21645918472e-05
ko04971	Gastric acid secretion	22/606	98/7206	1.49345884999e-05
ko04730	Long-term depression	19/606	78/7206	1.66676759302e-05
ko05030	Cocaine addiction	18/606	73/7206	2.32088803053e-05
ko04360	Axon guidance	39/606	233/7206	3.13227645673e-05
ko04514	Cell adhesion molecules (CAMs)	25/606	130/7206	7.5568766671e-05
ko04260	Cardiac muscle contraction	20/606	98/7206	0.000150095524418
ko04912	GnRH signaling pathway	23/606	122/7206	0.000194653052241
ko04750	Inflammatory mediator regulation of TRP channels	23/606	122/7206	0.000194653052241
ko04740	Olfactory transduction	17/606	80/7206	0.000279841500184
ko05014	Amyotrophic lateral sclerosis (ALS)	16/606	74/7206	0.000341279377648
ko04930	Type II diabetes mellitus	13/606	54/7206	0.000405193118002
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/606	14/7206	0.000575838721634
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	16/606	79/7206	0.000736867256368
ko04745	Phototransduction - fly	10/606	38/7206	0.000889583327396
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/606	59/7206	0.00100097036145
ko04071	Sphingolipid signaling pathway	26/606	162/7206	0.00133677578607
ko05322	Systemic lupus erythematosus	3/606	151/7206	0.00160573069915
ko05203	Viral carcinogenesis	10/606	277/7206	0.00185146920702
ko04110	Cell cycle	3/606	145/7206	0.00226403678918
ko04924	Renin secretion	16/606	86/7206	0.00240095377778
ko03013	RNA transport	4/606	166/7206	0.00257848098393
ko05168	Herpes simplex infection	5/606	182/7206	0.00267556294579
ko05414	Dilated cardiomyopathy	19/606	112/7206	0.00288025487802
ko04540	Gap junction	21/606	128/7206	0.00313472253907
ko05231	Choline metabolism in cancer	21/606	134/7206	0.00440966450252
ko04918	Thyroid hormone synthesis	15/606	86/7206	0.00543720916378
ko04014	Ras signaling pathway	37/606	279/7206	0.00555829497406
ko04960	Aldosterone-regulated sodium reabsorption	9/606	41/7206	0.00601717194192
ko00240	Pyrimidine metabolism	2/606	110/7206	0.00818279774202
ko04371	Apelin signaling pathway	25/606	177/7206	0.00878794902517
ko04722	Neurotrophin signaling pathway	23/606	160/7206	0.00924583332131
ko04915	Estrogen signaling pathway	20/606	131/7206	0.00974831390507
ko00562	Inositol phosphate metabolism	15/606	89/7206	0.0103942749428
ko04270	Vascular smooth muscle contraction	22/606	154/7206	0.0120671920262
ko05162	Measles	3/606	120/7206	0.0124086135143
ko04610	Complement and coagulation cascades	1/606	79/7206	0.0133900112112
ko03008	Ribosome biogenesis in eukaryotes	1/606	79/7206	0.0133900112112
ko05110	Vibrio cholerae infection	11/606	63/7206	0.0187266160779
ko05164	Influenza A	6/606	167/7206	0.0226927346938
ko05034	Alcoholism	30/606	238/7206	0.0233803627582
ko04012	ErbB signaling pathway	16/606	109/7206	0.0233877036128
ko04710	Circadian rhythm	8/606	43/7206	0.0249088220178
ko05410	Hypertrophic cardiomyopathy (HCM)	15/606	100/7206	0.0269544510658
ko04964	Proximal tubule bicarbonate reclamation	6/606	29/7206	0.0308501942836
ko04060	Cytokine-cytokine receptor interaction	8/606	191/7206	0.0333744194179
ko04923	Regulation of lipolysis in adipocytes	12/606	77/7206	0.0352582828956
ko04141	Protein processing in endoplasmic reticulum	8/606	184/7206	0.0429816417427
ko04916	Melanogenesis	19/606	142/7206	0.0448521335759
ko04137	Mitophagy - animal	2/606	82/7206	0.0451365399144
ko04919	Thyroid hormone signaling pathway	19/606	143/7206	0.0458155754951
ko04015	Rap1 signaling pathway	33/606	278/7206	0.0461582920581