ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko00120	Primary bile acid biosynthesis	12/548	20/7206	2.38413367875e-09
ko00350	Tyrosine metabolism	14/548	33/7206	3.88837934215e-08
ko04380	Osteoclast differentiation	29/548	134/7206	1.80684518034e-07
ko04064	NF-kappa B signaling pathway	23/548	96/7206	5.12808972815e-07
ko00360	Phenylalanine metabolism	9/548	17/7206	1.11468243399e-06
ko05150	Staphylococcus aureus infection	13/548	36/7206	1.11608862358e-06
ko04621	NOD-like receptor signaling pathway	30/548	157/7206	1.86509568598e-06
ko04146	Peroxisome	21/548	89/7206	2.0985471405e-06
ko04060	Cytokine-cytokine receptor interaction	34/548	191/7206	2.31903162962e-06
ko04610	Complement and coagulation cascades	19/548	79/7206	4.74574815773e-06
ko04620	Toll-like receptor signaling pathway	21/548	100/7206	1.48631443398e-05
ko05034	Alcoholism	3/548	238/7206	1.56752394712e-05
ko00071	Fatty acid degradation	13/548	45/7206	1.8618107454e-05
ko05164	Influenza A	29/548	167/7206	2.09645660391e-05
ko00643	Styrene degradation	4/548	4/7206	3.31086648746e-05
ko00982	Drug metabolism - cytochrome P450	11/548	37/7206	6.13198998432e-05
ko00380	Tryptophan metabolism	13/548	50/7206	6.35279257408e-05
ko05162	Measles	22/548	120/7206	8.49950947919e-05
ko03320	PPAR signaling pathway	15/548	69/7206	0.000163290914293
ko05204	Chemical carcinogenesis	12/548	48/7206	0.000182263382907
ko03040	Spliceosome	1/548	145/7206	0.000203912348483
ko00983	Drug metabolism - other enzymes	11/548	42/7206	0.000216433728345
ko05340	Primary immunodeficiency	9/548	30/7206	0.000267143050388
ko04650	Natural killer cell mediated cytotoxicity	18/548	97/7206	0.000315858908715
ko00590	Arachidonic acid metabolism	12/548	52/7206	0.000407824986794
ko05140	Leishmaniasis	15/548	75/7206	0.000428988642149
ko00362	Benzoate degradation	4/548	6/7206	0.000438495394765
ko00950	Isoquinoline alkaloid biosynthesis	5/548	10/7206	0.000456133016095
ko05145	Toxoplasmosis	21/548	126/7206	0.000523664294997
ko00980	Metabolism of xenobiotics by cytochrome P450	10/548	40/7206	0.000625751585413
ko04622	RIG-I-like receptor signaling pathway	13/548	62/7206	0.000638244675076
ko05133	Pertussis	16/548	87/7206	0.000743832366661
ko00640	Propanoate metabolism	9/548	34/7206	0.00074422403094
ko00140	Steroid hormone biosynthesis	10/548	41/7206	0.000772347927751
ko04630	Jak-STAT signaling pathway	21/548	132/7206	0.00122324500754
ko04110	Cell cycle	2/548	145/7206	0.00135165900197
ko04660	T cell receptor signaling pathway	20/548	124/7206	0.00157128192508
ko01212	Fatty acid metabolism	12/548	60/7206	0.00158066027235
ko00960	Tropane, piperidine and pyridine alkaloid biosynthesis	3/548	4/7206	0.00165099850514
ko03013	RNA transport	3/548	166/7206	0.00165456777795
ko05144	Malaria	10/548	45/7206	0.00166789869437
ko00330	Arginine and proline metabolism	12/548	61/7206	0.00183522997044
ko00280	Valine, leucine and isoleucine degradation	11/548	54/7206	0.0021008947428
ko00592	alpha-Linolenic acid metabolism	6/548	19/7206	0.00216593404444
ko05160	Hepatitis C	22/548	153/7206	0.00311202701733
ko04662	B cell receptor signaling pathway	15/548	88/7206	0.00328870253542
ko05323	Rheumatoid arthritis	15/548	89/7206	0.00350648045815
ko04723	Retrograde endocannabinoid signaling	4/548	175/7206	0.00361782638226
ko00830	Retinol metabolism	9/548	42/7206	0.00366411087687
ko00051	Fructose and mannose metabolism	9/548	42/7206	0.00366411087687
ko04611	Platelet activation	23/548	163/7206	0.00388561214071
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	3/548	5/7206	0.00389418636965
ko03010	Ribosome	2/548	129/7206	0.00399493429809
ko04137	Mitophagy - animal	14/548	82/7206	0.00470254918688
ko00920	Sulfur metabolism	4/548	10/7206	0.00479554676396
ko04672	Intestinal immune network for IgA production	8/548	37/7206	0.00570922074054
ko04080	Neuroactive ligand-receptor interaction	18/548	423/7206	0.00588428606226
ko04540	Gap junction	2/548	128/7206	0.00603467734204
ko04932	Non-alcoholic fatty liver disease (NAFLD)	24/548	182/7206	0.00679714068474
ko00130	Ubiquinone and other terpenoid-quinone biosynthesis	4/548	11/7206	0.00708775515358
ko04728	Dopaminergic synapse	5/548	185/7206	0.00710118902653
ko04612	Antigen processing and presentation	13/548	77/7206	0.00712752549451
ko00480	Glutathione metabolism	10/548	55/7206	0.00770251455148
ko04933	AGE-RAGE signaling pathway in diabetic complications	19/548	135/7206	0.00793411492404
ko04659	Th17 cell differentiation	16/548	106/7206	0.00815156322307
ko05321	Inflammatory bowel disease (IBD)	10/548	56/7206	0.00875837150288
ko04310	Wnt signaling pathway	5/548	181/7206	0.00977842013292
ko01200	Carbon metabolism	18/548	128/7206	0.0103688452073
ko04623	Cytosolic DNA-sensing pathway	8/548	41/7206	0.0108097511238
ko05142	Chagas disease (American trypanosomiasis)	18/548	130/7206	0.011400287922
ko04360	Axon guidance	8/548	233/7206	0.0114739970628
ko05134	Legionellosis	12/548	74/7206	0.0121604123376
ko05167	Kaposi's sarcoma-associated herpesvirus infection	24/548	191/7206	0.0125140407842
ko04668	TNF signaling pathway	17/548	120/7206	0.0132097629159
ko01524	Platinum drug resistance	12/548	76/7206	0.0139184111204
ko05168	Herpes simplex infection	23/548	182/7206	0.0150682107004
ko04390	Hippo signaling pathway	6/548	188/7206	0.0170615203649
ko04658	Th1 and Th2 cell differentiation	14/548	96/7206	0.0175419483234
ko00100	Steroid biosynthesis	5/548	21/7206	0.0182972995145
ko00620	Pyruvate metabolism	8/548	46/7206	0.0211625064145
ko04217	Necroptosis	22/548	178/7206	0.0212000112181
ko04210	Apoptosis	22/548	180/7206	0.022606817168
ko05152	Tuberculosis	23/548	187/7206	0.0238348651472
ko05418	Fluid shear stress and atherosclerosis	21/548	173/7206	0.0288259218603
ko04740	Olfactory transduction	1/548	80/7206	0.0302235178314
ko00220	Arginine biosynthesis	5/548	24/7206	0.0316749392657
ko04713	Circadian entrainment	4/548	136/7206	0.0333170410389
ko04911	Insulin secretion	3/548	117/7206	0.0338276828908
ko04666	Fc gamma R-mediated phagocytosis	16/548	122/7206	0.0358925457807
ko05203	Viral carcinogenesis	12/548	277/7206	0.0366557534028
ko04062	Chemokine signaling pathway	23/548	201/7206	0.0426904864872
ko04724	Glutamatergic synapse	5/548	152/7206	0.0429157045809
ko00650	Butanoate metabolism	5/548	26/7206	0.0432855302666
ko00020	Citrate cycle (TCA cycle)	6/548	35/7206	0.0461370672713
ko00500	Starch and sucrose metabolism	6/548	35/7206	0.0461370672713
ko04664	Fc epsilon RI signaling pathway	11/548	77/7206	0.0464697054864
ko04727	GABAergic synapse	3/548	110/7206	0.046481252073
ko05032	Morphine addiction	3/548	110/7206	0.046481252073
ko00281	Geraniol degradation	2/548	5/7206	0.0494700667907
ko00710	Carbon fixation in photosynthetic organisms	5/548	27/7206	0.0499307849376