ko pathway ratio_in_study ratio_in_pop p_value ko04360 Axon guidance 30/319 233/7206 1.02880641443e-07 ko04728 Dopaminergic synapse 26/319 185/7206 1.31896804002e-07 ko05033 Nicotine addiction 12/319 56/7206 4.44061821773e-06 ko04725 Cholinergic synapse 21/319 160/7206 6.71237497528e-06 ko04721 Synaptic vesicle cycle 14/319 80/7206 8.89070736631e-06 ko04724 Glutamatergic synapse 20/319 152/7206 1.07468040979e-05 ko04950 Maturity onset diabetes of the young 8/319 29/7206 2.56441844534e-05 ko05032 Morphine addiction 15/319 110/7206 9.10394419853e-05 ko04514 Cell adhesion molecules (CAMs) 16/319 130/7206 0.00018384859233 ko04727 GABAergic synapse 14/319 110/7206 0.000325631841159 ko04080 Neuroactive ligand-receptor interaction 35/319 423/7206 0.000331396045569 ko05217 Basal cell carcinoma 10/319 68/7206 0.000740886448894 ko04713 Circadian entrainment 15/319 136/7206 0.000944472980098 ko04723 Retrograde endocannabinoid signaling 18/319 175/7206 0.00102786625466 ko05014 Amyotrophic lateral sclerosis (ALS) 10/319 74/7206 0.0014476349186 ko04550 Signaling pathways regulating pluripotency of stem cells 17/319 165/7206 0.00148280350437 ko04911 Insulin secretion 13/319 117/7206 0.00190465426097 ko05224 Breast cancer 17/319 174/7206 0.00207320989973 ko04141 Protein processing in endoplasmic reticulum 1/319 184/7206 0.00523932439576 ko04974 Protein digestion and absorption 10/319 96/7206 0.00965986557682 ko05203 Viral carcinogenesis 4/319 277/7206 0.010371073645 ko04611 Platelet activation 1/319 163/7206 0.0105753339606 ko04151 PI3K-Akt signaling pathway 28/319 390/7206 0.0107166116265 ko04340 Hedgehog signaling pathway 7/319 58/7206 0.0134815643394 ko04261 Adrenergic signaling in cardiomyocytes 17/319 205/7206 0.0139411616087 ko04961 Endocrine and other factor-regulated calcium reabsorption 7/319 59/7206 0.0147350379185 ko05030 Cocaine addiction 8/319 73/7206 0.0148406500004 ko04391 Hippo signaling pathway - fly 9/319 90/7206 0.017632629543 ko04060 Cytokine-cytokine receptor interaction 2/319 191/7206 0.0183279260655 ko05031 Amphetamine addiction 9/319 91/7206 0.018834692811 ko04330 Notch signaling pathway 7/319 62/7206 0.0189915110283 ko04726 Serotonergic synapse 12/319 137/7206 0.019893977505 ko00604 Glycosphingolipid biosynthesis - ganglio series 3/319 14/7206 0.0217492717805 ko03040 Spliceosome 1/319 145/7206 0.0221099284318 ko04010 MAPK signaling pathway 23/319 321/7206 0.0248152446867 ko04341 Hedgehog signaling pathway - fly 5/319 38/7206 0.0249280387216 ko05168 Herpes simplex infection 2/319 182/7206 0.0258267127789 ko04932 Non-alcoholic fatty liver disease (NAFLD) 2/319 182/7206 0.0258267127789 ko05202 Transcriptional misregulation in cancer 15/319 188/7206 0.0281863730765 ko04120 Ubiquitin mediated proteolysis 1/319 138/7206 0.0326244770991 ko03013 RNA transport 2/319 166/7206 0.0348160187002 ko04964 Proximal tubule bicarbonate reclamation 4/319 29/7206 0.0373747369131 ko05200 Pathways in cancer 31/319 492/7206 0.0408276721365 ko00603 Glycosphingolipid biosynthesis - globo and isoglobo series 2/319 8/7206 0.0458344429886 ko00190 Oxidative phosphorylation 1/319 127/7206 0.0458458971948 ko04621 NOD-like receptor signaling pathway 2/319 157/7206 0.0486556010473