ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	137/903	423/7206	1.39998069942e-28
ko04724	Glutamatergic synapse	66/903	152/7206	8.55804856833e-22
ko05033	Nicotine addiction	37/903	56/7206	8.63705876287e-21
ko04721	Synaptic vesicle cycle	44/903	80/7206	6.50616262953e-20
ko04728	Dopaminergic synapse	66/903	185/7206	1.94901068251e-16
ko04713	Circadian entrainment	50/903	136/7206	2.58002810267e-13
ko04727	GABAergic synapse	43/903	110/7206	1.11152962466e-12
ko05032	Morphine addiction	43/903	110/7206	1.11152962466e-12
ko04725	Cholinergic synapse	52/903	160/7206	2.10375143186e-11
ko04723	Retrograde endocannabinoid signaling	52/903	175/7206	8.85807059201e-10
ko04024	cAMP signaling pathway	71/903	279/7206	1.74341809669e-09
ko04911	Insulin secretion	39/903	117/7206	3.14940774945e-09
ko04360	Axon guidance	62/903	233/7206	3.76952424714e-09
ko03040	Spliceosome	1/903	145/7206	1.48080085922e-07
ko05031	Amphetamine addiction	30/903	91/7206	2.76313937481e-07
ko05030	Cocaine addiction	26/903	73/7206	3.10777089752e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/903	74/7206	4.23021438564e-07
ko04261	Adrenergic signaling in cardiomyocytes	52/903	205/7206	4.74884019447e-07
ko04726	Serotonergic synapse	39/903	137/7206	5.78738846757e-07
ko04060	Cytokine-cytokine receptor interaction	5/903	191/7206	2.01861915407e-06
ko05168	Herpes simplex infection	5/903	182/7206	4.04443314386e-06
ko05203	Viral carcinogenesis	12/903	277/7206	4.32609857282e-06
ko04010	MAPK signaling pathway	67/903	321/7206	1.96426875576e-05
ko04514	Cell adhesion molecules (CAMs)	34/903	130/7206	2.11491101887e-05
ko04120	Ubiquitin mediated proteolysis	3/903	138/7206	2.21921399966e-05
ko03013	RNA transport	5/903	166/7206	2.47947738258e-05
ko04966	Collecting duct acid secretion	12/903	26/7206	2.50189296142e-05
ko05164	Influenza A	5/903	167/7206	2.5141667244e-05
ko04742	Taste transduction	20/903	61/7206	2.94151715049e-05
ko04720	Long-term potentiation	27/903	99/7206	7.94889253297e-05
ko05162	Measles	3/903	120/7206	0.000220898449478
ko04970	Salivary secretion	25/903	95/7206	0.000231919849868
ko04744	Phototransduction	13/903	36/7206	0.000247962045193
ko04921	Oxytocin signaling pathway	45/903	209/7206	0.000264902905986
ko04621	NOD-like receptor signaling pathway	6/903	157/7206	0.000332273954137
ko04730	Long-term depression	21/903	78/7206	0.000465001459203
ko03008	Ribosome biogenesis in eukaryotes	1/903	79/7206	0.000488638377387
ko04260	Cardiac muscle contraction	25/903	98/7206	0.000533768863479
ko04141	Protein processing in endoplasmic reticulum	9/903	184/7206	0.00064913904151
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/903	14/7206	0.000731507556611
ko04146	Peroxisome	2/903	89/7206	0.00104922898114
ko04214	Apoptosis - fly	1/903	72/7206	0.00108804049874
ko04540	Gap junction	29/903	128/7206	0.00112818376863
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/903	79/7206	0.00167447191439
ko05322	Systemic lupus erythematosus	7/903	151/7206	0.00169212255646
ko04950	Maturity onset diabetes of the young	10/903	29/7206	0.00192665468544
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/903	59/7206	0.00223994839157
ko04064	NF-kappa B signaling pathway	3/903	96/7206	0.00271433926728
ko00561	Glycerolipid metabolism	1/903	63/7206	0.0035700698861
ko04640	Hematopoietic cell lineage	1/903	64/7206	0.00363052813877
ko01200	Carbon metabolism	6/903	128/7206	0.00432002215023
ko04924	Renin secretion	20/903	86/7206	0.00488514530767
ko05169	Epstein-Barr virus infection	13/903	206/7206	0.00517117845015
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/903	15/7206	0.0069874509844
ko04110	Cell cycle	8/903	145/7206	0.00738670123189
ko04020	Calcium signaling pathway	48/903	265/7206	0.00782656491056
ko00240	Pyrimidine metabolism	5/903	110/7206	0.0082571564594
ko04140	Autophagy - animal	10/903	164/7206	0.00853225548616
ko04740	Olfactory transduction	18/903	80/7206	0.0105351131083
ko04138	Autophagy - yeast	3/903	81/7206	0.0107601733523
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	8/903	26/7206	0.0115766327302
ko05110	Vibrio cholerae infection	15/903	63/7206	0.0116815714583
ko04022	cGMP-PKG signaling pathway	40/903	216/7206	0.0117576220048
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/903	182/7206	0.0121850782063
ko04014	Ras signaling pathway	49/903	279/7206	0.0125433127865
ko04972	Pancreatic secretion	23/903	111/7206	0.0132775701755
ko04612	Antigen processing and presentation	3/903	77/7206	0.0151667453763
ko04915	Estrogen signaling pathway	26/903	131/7206	0.0157620880884
ko05140	Leishmaniasis	3/903	75/7206	0.0213716279046
ko04964	Proximal tubule bicarbonate reclamation	8/903	29/7206	0.0226603166555
ko04391	Hippo signaling pathway - fly	19/903	90/7206	0.023060370496
ko00620	Pyruvate metabolism	1/903	46/7206	0.0251626907464
ko03420	Nucleotide excision repair	1/903	46/7206	0.0251626907464
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/903	92/7206	0.0252385086974
ko04976	Bile secretion	17/903	80/7206	0.0257521087647
ko05418	Fluid shear stress and atherosclerosis	12/903	173/7206	0.0262885803824
ko04962	Vasopressin-regulated water reabsorption	13/903	58/7206	0.0286802058098
ko04217	Necroptosis	13/903	178/7206	0.0294640434502
ko03018	RNA degradation	4/903	84/7206	0.0296342068543
ko04971	Gastric acid secretion	20/903	98/7206	0.0296353633
ko00330	Arginine and proline metabolism	2/903	61/7206	0.0297918618276
ko05224	Breast cancer	31/903	174/7206	0.0369974452286
ko03022	Basal transcription factors	1/903	44/7206	0.037248254072
ko05166	HTLV-I infection	25/903	292/7206	0.0375356378712
ko05144	Malaria	1/903	45/7206	0.0381713156464
ko00071	Fatty acid degradation	1/903	45/7206	0.0381713156464
ko05205	Proteoglycans in cancer	23/903	271/7206	0.0394997539929
ko00480	Glutathione metabolism	2/903	55/7206	0.0407995458464
ko04611	Platelet activation	12/903	163/7206	0.0418537020869
ko03320	PPAR signaling pathway	3/903	69/7206	0.0420565939424
ko04015	Rap1 signaling pathway	46/903	278/7206	0.0422008502719
ko05034	Alcoholism	40/903	238/7206	0.0464657001391
ko00564	Glycerophospholipid metabolism	6/903	99/7206	0.0471850278607
ko05146	Amoebiasis	6/903	99/7206	0.0471850278607
ko05161	Hepatitis B	13/903	173/7206	0.0472371005157
ko04072	Phospholipase D signaling pathway	34/903	197/7206	0.0489472897081