ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 29/359 191/7206 5.71556204892e-08 ko00120 Primary bile acid biosynthesis 8/359 20/7206 2.61036641829e-06 ko00350 Tyrosine metabolism 9/359 33/7206 2.27298862557e-05 ko00982 Drug metabolism - cytochrome P450 8/359 37/7206 0.000379509636771 ko00643 Styrene degradation 3/359 4/7206 0.000472497380628 ko04610 Complement and coagulation cascades 12/359 79/7206 0.000483861293714 ko05034 Alcoholism 2/359 238/7206 0.000716968985499 ko05164 Influenza A 19/359 167/7206 0.000784838437908 ko00140 Steroid hormone biosynthesis 8/359 41/7206 0.000788895353234 ko00565 Ether lipid metabolism 8/359 42/7206 0.000933000766315 ko00590 Arachidonic acid metabolism 9/359 52/7206 0.000937090748336 ko04380 Osteoclast differentiation 16/359 134/7206 0.000960723726789 ko04650 Natural killer cell mediated cytotoxicity 13/359 97/7206 0.000972754492769 ko04710 Circadian rhythm 8/359 43/7206 0.0010974547327 ko05321 Inflammatory bowel disease (IBD) 9/359 56/7206 0.0016189032123 ko00592 alpha-Linolenic acid metabolism 5/359 19/7206 0.00194343548194 ko04672 Intestinal immune network for IgA production 7/359 37/7206 0.00202254239932 ko04666 Fc gamma R-mediated phagocytosis 14/359 122/7206 0.00286143313913 ko04611 Platelet activation 17/359 163/7206 0.00320902408573 ko03013 RNA transport 1/359 166/7206 0.00332515306462 ko00564 Glycerophospholipid metabolism 12/359 99/7206 0.00357047615902 ko00051 Fructose and mannose metabolism 7/359 42/7206 0.00428001274115 ko00480 Glutathione metabolism 8/359 55/7206 0.00547913991297 ko05152 Tuberculosis 18/359 187/7206 0.00608597169013 ko03320 PPAR signaling pathway 9/359 69/7206 0.00686269574441 ko04137 Mitophagy - animal 10/359 82/7206 0.00722720971569 ko04621 NOD-like receptor signaling pathway 16/359 157/7206 0.00774563830296 ko05150 Staphylococcus aureus infection 6/359 36/7206 0.00802544266698 ko00360 Phenylalanine metabolism 4/359 17/7206 0.00859833877543 ko04660 T cell receptor signaling pathway 13/359 124/7206 0.0102177094739 ko00330 Arginine and proline metabolism 8/359 61/7206 0.0102355196947 ko05203 Viral carcinogenesis 5/359 277/7206 0.0103658521564 ko04110 Cell cycle 1/359 145/7206 0.010470067284 ko05145 Toxoplasmosis 13/359 126/7206 0.0112344465278 ko00950 Isoquinoline alkaloid biosynthesis 3/359 10/7206 0.0113232311802 ko05140 Leishmaniasis 9/359 75/7206 0.0117196992191 ko04662 B cell receptor signaling pathway 10/359 88/7206 0.0117252756528 ko04146 Peroxisome 10/359 89/7206 0.0126445996168 ko00980 Metabolism of xenobiotics by cytochrome P450 6/359 40/7206 0.013387841384 ko04960 Aldosterone-regulated sodium reabsorption 6/359 41/7206 0.0150448123506 ko05340 Primary immunodeficiency 5/359 30/7206 0.0151969434235 ko04120 Ubiquitin mediated proteolysis 1/359 138/7206 0.0153648183771 ko04512 ECM-receptor interaction 9/359 79/7206 0.0161511444842 ko05162 Measles 12/359 120/7206 0.018095512551 ko03010 Ribosome 1/359 129/7206 0.0219161652649 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/359 5/7206 0.0223905368882 ko04630 Jak-STAT signaling pathway 13/359 132/7206 0.0229404996408 ko05231 Choline metabolism in cancer 13/359 134/7206 0.0238986112359 ko04933 AGE-RAGE signaling pathway in diabetic complications 13/359 135/7206 0.0244611573234 ko04390 Hippo signaling pathway 3/359 188/7206 0.025934323334 ko00220 Arginine biosynthesis 4/359 24/7206 0.0291965362772 ko05204 Chemical carcinogenesis 6/359 48/7206 0.0307426029039 ko01040 Biosynthesis of unsaturated fatty acids 4/359 25/7206 0.0334351556219 ko00380 Tryptophan metabolism 6/359 50/7206 0.0366669316398 ko04072 Phospholipase D signaling pathway 16/359 197/7206 0.046043078453 ko04068 FoxO signaling pathway 14/359 167/7206 0.0474140996721 ko00966 Glucosinolate biosynthesis 1/359 1/7206 0.0498195947821 ko04723 Retrograde endocannabinoid signaling 3/359 175/7206 0.0499300675627