ko pathway ratio_in_study ratio_in_pop p_value ko05032 Morphine addiction 10/145 110/7206 6.71285884862e-05 ko04070 Phosphatidylinositol signaling system 10/145 112/7206 7.82793760572e-05 ko04728 Dopaminergic synapse 13/145 185/7206 8.25205937044e-05 ko04911 Insulin secretion 10/145 117/7206 0.000113248604198 ko04724 Glutamatergic synapse 11/145 152/7206 0.00022879529989 ko04925 Aldosterone synthesis and secretion 9/145 105/7206 0.000245597812067 ko04713 Circadian entrainment 10/145 136/7206 0.000389897358087 ko00562 Inositol phosphate metabolism 8/145 89/7206 0.00039547577943 ko04971 Gastric acid secretion 8/145 98/7206 0.000756977400775 ko04721 Synaptic vesicle cycle 7/145 80/7206 0.00107686112699 ko04725 Cholinergic synapse 10/145 160/7206 0.00138442159313 ko04727 GABAergic synapse 8/145 110/7206 0.00160995138507 ko04726 Serotonergic synapse 9/145 137/7206 0.00169971754895 ko05010 Alzheimer's disease 11/145 202/7206 0.00243406371222 ko04020 Calcium signaling pathway 13/145 265/7206 0.00253739209793 ko04723 Retrograde endocannabinoid signaling 10/145 175/7206 0.00269328685716 ko04261 Adrenergic signaling in cardiomyocytes 11/145 205/7206 0.00273061569931 ko04921 Oxytocin signaling pathway 11/145 209/7206 0.00317083036737 ko04720 Long-term potentiation 7/145 99/7206 0.00367791733117 ko05033 Nicotine addiction 5/145 56/7206 0.00515764876752 ko04072 Phospholipase D signaling pathway 10/145 197/7206 0.00623660926863 ko04745 Phototransduction - fly 4/145 38/7206 0.00682680422061 ko04144 Endocytosis 14/145 342/7206 0.00952603472865 ko05031 Amphetamine addiction 6/145 91/7206 0.00982423154835 ko04022 cGMP-PKG signaling pathway 10/145 216/7206 0.0115832803747 ko04970 Salivary secretion 6/145 95/7206 0.0120026570692 ko04024 cAMP signaling pathway 12/145 279/7206 0.0133732395853 ko04260 Cardiac muscle contraction 6/145 98/7206 0.0138456258089 ko04922 Glucagon signaling pathway 7/145 128/7206 0.0144528210172 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/145 1/7206 0.0201221204552 ko04011 MAPK signaling pathway - yeast 4/145 53/7206 0.0214982192266 ko04740 Olfactory transduction 5/145 80/7206 0.0221570887578 ko04711 Circadian rhythm - fly 2/145 13/7206 0.0271246773764 ko04340 Hedgehog signaling pathway 4/145 58/7206 0.0288564053167 ko04924 Renin secretion 5/145 86/7206 0.0291972465883 ko04918 Thyroid hormone synthesis 5/145 86/7206 0.0291972465883 ko00680 Methane metabolism 3/145 34/7206 0.0302984732898 ko04961 Endocrine and other factor-regulated calcium reabsorption 4/145 59/7206 0.0304864593266 ko04912 GnRH signaling pathway 6/145 122/7206 0.036078595587 ko04750 Inflammatory mediator regulation of TRP channels 6/145 122/7206 0.036078595587 ko05110 Vibrio cholerae infection 4/145 63/7206 0.037542880264 ko04139 Mitophagy - yeast 3/145 37/7206 0.0376735743481 ko01051 Biosynthesis of ansamycins 1/145 2/7206 0.0398420777817 ko00254 Aflatoxin biosynthesis 1/145 2/7206 0.0398420777817 ko04540 Gap junction 6/145 128/7206 0.0439633772544 ko00061 Fatty acid biosynthesis 2/145 17/7206 0.0448883235771 ko04626 Plant-pathogen interaction 2/145 18/7206 0.049847214661