ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	66/725	152/7206	2.49999437831e-27
ko05033	Nicotine addiction	39/725	56/7206	9.19123810454e-27
ko04080	Neuroactive ligand-receptor interaction	116/725	423/7206	8.16573277064e-26
ko05032	Morphine addiction	49/725	110/7206	4.07805484606e-21
ko04727	GABAergic synapse	48/725	110/7206	3.07371637839e-20
ko04713	Circadian entrainment	52/725	136/7206	9.82720667838e-19
ko04723	Retrograde endocannabinoid signaling	58/725	175/7206	2.49314089671e-17
ko04721	Synaptic vesicle cycle	37/725	80/7206	6.80253383043e-17
ko04744	Phototransduction	24/725	36/7206	3.14640831607e-16
ko04728	Dopaminergic synapse	56/725	185/7206	8.35052794452e-15
ko04024	cAMP signaling pathway	68/725	279/7206	1.39667119788e-12
ko04725	Cholinergic synapse	47/725	160/7206	4.36947428127e-12
ko04740	Olfactory transduction	29/725	80/7206	2.46472576182e-10
ko04911	Insulin secretion	36/725	117/7206	3.58587953705e-10
ko04970	Salivary secretion	30/725	95/7206	5.45072139696e-09
ko04742	Taste transduction	23/725	61/7206	7.52644747489e-09
ko04726	Serotonergic synapse	37/725	137/7206	1.12791716969e-08
ko05203	Viral carcinogenesis	5/725	277/7206	6.18445075131e-08
ko05031	Amphetamine addiction	27/725	91/7206	1.36739198262e-07
ko04261	Adrenergic signaling in cardiomyocytes	45/725	205/7206	3.54532507104e-07
ko04921	Oxytocin signaling pathway	45/725	209/7206	5.47076928344e-07
ko04720	Long-term potentiation	27/725	99/7206	8.91722535692e-07
ko05030	Cocaine addiction	22/725	73/7206	1.4787524015e-06
ko04971	Gastric acid secretion	26/725	98/7206	2.50835162212e-06
ko04060	Cytokine-cytokine receptor interaction	3/725	191/7206	4.14902911608e-06
ko03040	Spliceosome	1/725	145/7206	4.82150517858e-06
ko04020	Calcium signaling pathway	51/725	265/7206	5.31997899312e-06
ko05164	Influenza A	2/725	167/7206	5.86138372829e-06
ko04924	Renin secretion	23/725	86/7206	8.20542868775e-06
ko04972	Pancreatic secretion	27/725	111/7206	9.59294326091e-06
ko04514	Cell adhesion molecules (CAMs)	30/725	130/7206	1.05632875387e-05
ko04120	Ubiquitin mediated proteolysis	1/725	138/7206	1.07681989713e-05
ko04022	cGMP-PKG signaling pathway	42/725	216/7206	2.5468291921e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	20/725	74/7206	2.68196864022e-05
ko04730	Long-term depression	20/725	78/7206	6.11503727409e-05
ko04810	Regulation of actin cytoskeleton	9/725	264/7206	6.13765165283e-05
ko04964	Proximal tubule bicarbonate reclamation	11/725	29/7206	6.2652700411e-05
ko05162	Measles	1/725	120/7206	8.22407610259e-05
ko05169	Epstein-Barr virus infection	6/725	206/7206	0.000137594716694
ko05322	Systemic lupus erythematosus	3/725	151/7206	0.000172354425116
ko03013	RNA transport	4/725	166/7206	0.000210726785727
ko04925	Aldosterone synthesis and secretion	23/725	105/7206	0.000253129587382
ko04976	Bile secretion	19/725	80/7206	0.0002761274977
ko04110	Cell cycle	3/725	145/7206	0.000373763406642
ko04978	Mineral absorption	12/725	40/7206	0.000384961238028
ko04966	Collecting duct acid secretion	9/725	26/7206	0.000648726512755
ko05205	Proteoglycans in cancer	12/725	271/7206	0.000896502116817
ko04260	Cardiac muscle contraction	21/725	98/7206	0.000948024540816
ko04540	Gap junction	25/725	128/7206	0.000961783203708
ko05168	Herpes simplex infection	6/725	182/7206	0.00100954788686
ko04630	Jak-STAT signaling pathway	3/725	132/7206	0.00107004035222
ko05215	Prostate cancer	2/725	111/7206	0.00120928340625
ko05166	HTLV-I infection	14/725	292/7206	0.00137043579378
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/725	59/7206	0.00172822051153
ko04621	NOD-like receptor signaling pathway	5/725	157/7206	0.0018111435213
ko04141	Protein processing in endoplasmic reticulum	7/725	184/7206	0.00260053688795
ko04510	Focal adhesion	11/725	240/7206	0.00295945380389
ko04010	MAPK signaling pathway	49/725	321/7206	0.00305960209073
ko04745	Phototransduction - fly	10/725	38/7206	0.00345738324638
ko03008	Ribosome biogenesis in eukaryotes	1/725	79/7206	0.00403179267939
ko05161	Hepatitis B	7/725	173/7206	0.00468609677926
ko05211	Renal cell carcinoma	2/725	96/7206	0.00535865989698
ko00830	Retinol metabolism	10/725	42/7206	0.00744697368199
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/725	182/7206	0.00818779747741
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/725	14/7206	0.00939547286422
ko05220	Chronic myeloid leukemia	2/725	85/7206	0.0106687885986
ko04520	Adherens junction	3/725	103/7206	0.0120475599744
ko05224	Breast cancer	8/725	174/7206	0.0144776477123
ko04064	NF-kappa B signaling pathway	3/725	96/7206	0.0164503147153
ko04330	Notch signaling pathway	1/725	62/7206	0.0185359587066
ko05034	Alcoholism	35/725	238/7206	0.0207855806716
ko04612	Antigen processing and presentation	2/725	77/7206	0.0216571157437
ko04610	Complement and coagulation cascades	2/725	79/7206	0.0220256827794
ko04218	Cellular senescence	9/725	177/7206	0.0224126745268
ko04217	Necroptosis	9/725	178/7206	0.0224746671305
ko04210	Apoptosis	9/725	180/7206	0.0228585222104
ko04974	Protein digestion and absorption	17/725	96/7206	0.0241617860086
ko04140	Autophagy - animal	8/725	164/7206	0.0246330751228
ko04550	Signaling pathways regulating pluripotency of stem cells	8/725	165/7206	0.0248799800397
ko00230	Purine metabolism	29/725	194/7206	0.0285923372757
ko04626	Plant-pathogen interaction	5/725	18/7206	0.0286881917952
ko04918	Thyroid hormone synthesis	15/725	86/7206	0.0294128160639
ko04668	TNF signaling pathway	5/725	120/7206	0.0305850983047
ko00310	Lysine degradation	2/725	73/7206	0.0307229781934
ko05140	Leishmaniasis	2/725	75/7206	0.0313016556499
ko05110	Vibrio cholerae infection	12/725	63/7206	0.0313555407423
ko04973	Carbohydrate digestion and absorption	9/725	42/7206	0.0329948680719
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/725	79/7206	0.0355209658837
ko00280	Valine, leucine and isoleucine degradation	1/725	54/7206	0.0394958989681
ko00520	Amino sugar and nucleotide sugar metabolism	1/725	55/7206	0.03990091975
ko00480	Glutathione metabolism	1/725	55/7206	0.03990091975
ko05416	Viral myocarditis	1/725	55/7206	0.03990091975
ko04072	Phospholipase D signaling pathway	29/725	197/7206	0.0399419509713
ko04371	Apelin signaling pathway	26/725	177/7206	0.0428903581058
ko03018	RNA degradation	3/725	84/7206	0.0440020485199
ko05218	Melanoma	3/725	85/7206	0.0442399633996
ko04214	Apoptosis - fly	2/725	72/7206	0.0452875216544
ko04750	Inflammatory mediator regulation of TRP channels	19/725	122/7206	0.0478791839237
ko05016	Huntington's disease	13/725	215/7206	0.049575018934
ko04660	T cell receptor signaling pathway	6/725	124/7206	0.0498933357912