ko pathway ratio_in_study ratio_in_pop p_value ko04744 Phototransduction 12/111 36/7206 8.95463401909e-14 ko04728 Dopaminergic synapse 14/111 185/7206 7.86347586569e-07 ko04024 cAMP signaling pathway 17/111 279/7206 1.0354423608e-06 ko04911 Insulin secretion 10/111 117/7206 1.12446848427e-05 ko05032 Morphine addiction 9/111 110/7206 4.47102328021e-05 ko04724 Glutamatergic synapse 10/111 152/7206 0.000107811630453 ko04713 Circadian entrainment 8/111 136/7206 0.0011302922799 ko04727 GABAergic synapse 7/111 110/7206 0.00147043185092 ko05033 Nicotine addiction 5/111 56/7206 0.00161991935162 ko00230 Purine metabolism 9/111 194/7206 0.00292395219722 ko05030 Cocaine addiction 5/111 73/7206 0.00518155231321 ko04723 Retrograde endocannabinoid signaling 8/111 175/7206 0.00543557300254 ko04740 Olfactory transduction 5/111 80/7206 0.00761960335348 ko05031 Amphetamine addiction 5/111 91/7206 0.0129081606044 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/111 1/7206 0.0154038301416 ko04972 Pancreatic secretion 5/111 111/7206 0.0279853894771 ko04072 Phospholipase D signaling pathway 7/111 197/7206 0.0319973437529 ko04721 Synaptic vesicle cycle 4/111 80/7206 0.0345087474115 ko04062 Chemokine signaling pathway 7/111 201/7206 0.0351298086051 ko04725 Cholinergic synapse 6/111 160/7206 0.0366356603306 ko04080 Neuroactive ligand-receptor interaction 12/111 423/7206 0.0381708800773 ko04261 Adrenergic signaling in cardiomyocytes 7/111 205/7206 0.0384605868934 ko04540 Gap junction 5/111 128/7206 0.0471777781267 ko04022 cGMP-PKG signaling pathway 7/111 216/7206 0.0486734394245 ko04514 Cell adhesion molecules (CAMs) 5/111 130/7206 0.0498459211667