ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	137/918	423/7206	8.09796884172e-28
ko05033	Nicotine addiction	32/918	56/7206	2.92888991606e-15
ko04724	Glutamatergic synapse	56/918	152/7206	1.68852771537e-14
ko04721	Synaptic vesicle cycle	35/918	80/7206	5.02052320614e-12
ko04713	Circadian entrainment	46/918	136/7206	1.1930643191e-10
ko04727	GABAergic synapse	40/918	110/7206	1.63513493746e-10
ko04911	Insulin secretion	41/918	117/7206	3.61642900352e-10
ko04728	Dopaminergic synapse	53/918	185/7206	4.64247624229e-09
ko05032	Morphine addiction	37/918	110/7206	9.53711473949e-09
ko04610	Complement and coagulation cascades	30/918	79/7206	1.00965604928e-08
ko04260	Cardiac muscle contraction	34/918	98/7206	1.57002429651e-08
ko04742	Taste transduction	25/918	61/7206	2.88638400311e-08
ko04725	Cholinergic synapse	46/918	160/7206	4.85118601239e-08
ko04261	Adrenergic signaling in cardiomyocytes	55/918	205/7206	4.88933442042e-08
ko03040	Spliceosome	1/918	145/7206	9.13636442833e-08
ko04723	Retrograde endocannabinoid signaling	48/918	175/7206	1.18730186328e-07
ko04974	Protein digestion and absorption	32/918	96/7206	1.22019749448e-07
ko04976	Bile secretion	28/918	80/7206	2.37204954735e-07
ko04978	Mineral absorption	18/918	40/7206	4.79660669004e-07
ko04740	Olfactory transduction	27/918	80/7206	8.93703286823e-07
ko04060	Cytokine-cytokine receptor interaction	5/918	191/7206	1.35499723405e-06
ko05162	Measles	1/918	120/7206	2.50429055503e-06
ko05164	Influenza A	4/918	167/7206	3.05358142515e-06
ko04950	Maturity onset diabetes of the young	14/918	29/7206	3.26645692559e-06
ko04024	cAMP signaling pathway	63/918	279/7206	3.51809045503e-06
ko04726	Serotonergic synapse	37/918	137/7206	6.08926390514e-06
ko04514	Cell adhesion molecules (CAMs)	35/918	130/7206	1.24954874726e-05
ko04970	Salivary secretion	28/918	95/7206	1.34736945043e-05
ko04744	Phototransduction	15/918	36/7206	1.38807602863e-05
ko04120	Ubiquitin mediated proteolysis	3/918	138/7206	1.48083369827e-05
ko03013	RNA transport	5/918	166/7206	1.69804985745e-05
ko04924	Renin secretion	25/918	86/7206	5.02678416203e-05
ko05203	Viral carcinogenesis	15/918	277/7206	6.63285332563e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/918	79/7206	0.000103388369788
ko05166	HTLV-I infection	17/918	292/7206	0.000105462756927
ko04964	Proximal tubule bicarbonate reclamation	12/918	29/7206	0.000110348023152
ko05030	Cocaine addiction	22/918	73/7206	0.00011227427796
ko04140	Autophagy - animal	6/918	164/7206	0.000117140271935
ko05014	Amyotrophic lateral sclerosis (ALS)	22/918	74/7206	0.00012352022927
ko04966	Collecting duct acid secretion	11/918	26/7206	0.000168647945989
ko05031	Amphetamine addiction	25/918	91/7206	0.000173164366208
ko05169	Epstein-Barr virus infection	10/918	206/7206	0.000184218736022
ko04921	Oxytocin signaling pathway	46/918	209/7206	0.00019187370852
ko04010	MAPK signaling pathway	64/918	321/7206	0.000207421250983
ko04621	NOD-like receptor signaling pathway	6/918	157/7206	0.000228958982785
ko05410	Hypertrophic cardiomyopathy (HCM)	26/918	100/7206	0.000367993413794
ko04141	Protein processing in endoplasmic reticulum	9/918	184/7206	0.000470869595557
ko03008	Ribosome biogenesis in eukaryotes	1/918	79/7206	0.00049297980724
ko05168	Herpes simplex infection	9/918	182/7206	0.000645547404661
ko04972	Pancreatic secretion	27/918	111/7206	0.00077313941864
ko04730	Long-term depression	21/918	78/7206	0.000832406491959
ko04977	Vitamin digestion and absorption	9/918	22/7206	0.00089614276058
ko00564	Glycerophospholipid metabolism	3/918	99/7206	0.00128317554119
ko04020	Calcium signaling pathway	52/918	265/7206	0.00130876624692
ko05161	Hepatitis B	9/918	173/7206	0.00163737479876
ko04145	Phagosome	35/918	162/7206	0.00171874655002
ko04540	Gap junction	29/918	128/7206	0.00180374865725
ko04512	ECM-receptor interaction	20/918	79/7206	0.0019374072244
ko04138	Autophagy - yeast	2/918	81/7206	0.00219868835383
ko04110	Cell cycle	7/918	145/7206	0.00228325608592
ko05414	Dilated cardiomyopathy	26/918	112/7206	0.0022923083475
ko00561	Glycerolipid metabolism	1/918	63/7206	0.00359730114344
ko04614	Renin-angiotensin system	7/918	18/7206	0.00473582282016
ko04217	Necroptosis	11/918	178/7206	0.00597541043896
ko00310	Lysine degradation	2/918	73/7206	0.00696301365563
ko03018	RNA degradation	3/918	84/7206	0.00762229815916
ko04973	Carbohydrate digestion and absorption	12/918	42/7206	0.00808373330193
ko04720	Long-term potentiation	22/918	99/7206	0.00886235148135
ko04022	cGMP-PKG signaling pathway	41/918	216/7206	0.00914762328027
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/918	182/7206	0.00931696955648
ko04150	mTOR signaling pathway	12/918	184/7206	0.00947972776149
ko04137	Mitophagy - animal	3/918	82/7206	0.0111197740141
ko04914	Progesterone-mediated oocyte maturation	5/918	104/7206	0.011121051158
ko05205	Proteoglycans in cancer	21/918	271/7206	0.0117775316425
ko04933	AGE-RAGE signaling pathway in diabetic complications	8/918	135/7206	0.0129758160636
ko04211	Longevity regulating pathway	7/918	123/7206	0.0138538169863
ko04660	T cell receptor signaling pathway	7/918	124/7206	0.0138806733984
ko04971	Gastric acid secretion	21/918	98/7206	0.0139846491835
ko04612	Antigen processing and presentation	3/918	77/7206	0.0151037260732
ko00830	Retinol metabolism	11/918	42/7206	0.0169390290278
ko00510	N-Glycan biosynthesis	1/918	50/7206	0.0171781990629
ko04630	Jak-STAT signaling pathway	8/918	132/7206	0.0172074664888
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/918	59/7206	0.0173025396329
ko04668	TNF signaling pathway	7/918	120/7206	0.0184953977888
ko04142	Lysosome	10/918	151/7206	0.0189610700052
ko05150	Staphylococcus aureus infection	10/918	36/7206	0.0194134012309
ko00600	Sphingolipid metabolism	2/918	63/7206	0.0205430795731
ko04658	Th1 and Th2 cell differentiation	5/918	96/7206	0.0206730574207
ko04064	NF-kappa B signaling pathway	5/918	96/7206	0.0206730574207
ko04657	IL-17 signaling pathway	4/918	87/7206	0.0218402138352
ko00250	Alanine, aspartate and glutamate metabolism	10/918	38/7206	0.0233524059581
ko00770	Pantothenate and CoA biosynthesis	5/918	14/7206	0.024715641775
ko03420	Nucleotide excision repair	1/918	46/7206	0.0250207262009
ko00910	Nitrogen metabolism	6/918	19/7206	0.0263127440441
ko04659	Th17 cell differentiation	6/918	106/7206	0.0265981136207
ko05016	Huntington's disease	17/918	215/7206	0.0290070684561
ko04218	Cellular senescence	13/918	177/7206	0.0294134196043
ko05206	MicroRNAs in cancer	13/918	177/7206	0.0294134196043
ko04113	Meiosis - yeast	3/918	70/7206	0.0295804815057
ko04214	Apoptosis - fly	3/918	72/7206	0.0306142533935
ko05110	Vibrio cholerae infection	14/918	63/7206	0.0342913150796
ko04975	Fat digestion and absorption	9/918	35/7206	0.0361162290212
ko00071	Fatty acid degradation	1/918	45/7206	0.0390415278419
ko05215	Prostate cancer	7/918	111/7206	0.0432423590581
ko04070	Phosphatidylinositol signaling system	7/918	112/7206	0.0438203210354
ko04620	Toll-like receptor signaling pathway	6/918	100/7206	0.0477324201432