ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 15/139 191/7206 3.53080702746e-06 ko04380 Osteoclast differentiation 11/139 134/7206 5.02527498554e-05 ko04610 Complement and coagulation cascades 8/139 79/7206 0.000128947648022 ko04630 Jak-STAT signaling pathway 10/139 132/7206 0.000217335386514 ko04650 Natural killer cell mediated cytotoxicity 8/139 97/7206 0.000533952191753 ko05321 Inflammatory bowel disease (IBD) 6/139 56/7206 0.000679555068705 ko05167 Kaposi's sarcoma-associated herpesvirus infection 11/139 191/7206 0.00110657332188 ko00051 Fructose and mannose metabolism 5/139 42/7206 0.00119081700681 ko05164 Influenza A 10/139 167/7206 0.00138900427195 ko05162 Measles 8/139 120/7206 0.00214287432715 ko04668 TNF signaling pathway 8/139 120/7206 0.00214287432715 ko04217 Necroptosis 10/139 178/7206 0.00223547836922 ko04064 NF-kappa B signaling pathway 7/139 96/7206 0.0024403267158 ko05145 Toxoplasmosis 8/139 126/7206 0.00290834324736 ko04620 Toll-like receptor signaling pathway 7/139 100/7206 0.00307529726966 ko05152 Tuberculosis 10/139 187/7206 0.00320188784602 ko05150 Staphylococcus aureus infection 4/139 36/7206 0.00483827857497 ko04672 Intestinal immune network for IgA production 4/139 37/7206 0.00534483903248 ko05133 Pertussis 6/139 87/7206 0.00649778083839 ko04666 Fc gamma R-mediated phagocytosis 7/139 122/7206 0.00907807095007 ko04660 T cell receptor signaling pathway 7/139 124/7206 0.00988422221476 ko04621 NOD-like receptor signaling pathway 8/139 157/7206 0.0107627944627 ko04611 Platelet activation 8/139 163/7206 0.0132915538946 ko05166 HTLV-I infection 12/139 292/7206 0.0135269464588 ko05140 Leishmaniasis 5/139 75/7206 0.014576606429 ko04664 Fc epsilon RI signaling pathway 5/139 77/7206 0.0161873060984 ko05340 Primary immunodeficiency 3/139 30/7206 0.0194949746811 ko05230 Central carbon metabolism in cancer 5/139 81/7206 0.019755557804 ko04919 Thyroid hormone signaling pathway 7/139 143/7206 0.0203398813594 ko05168 Herpes simplex infection 8/139 182/7206 0.0241720576025 ko04662 B cell receptor signaling pathway 5/139 88/7206 0.0271711522931 ko05160 Hepatitis C 7/139 153/7206 0.0281802656845 ko04922 Glucagon signaling pathway 6/139 128/7206 0.0369600160063 ko04658 Th1 and Th2 cell differentiation 5/139 96/7206 0.0375785203072 ko00254 Aflatoxin biosynthesis 1/139 2/7206 0.0382095034927 ko05142 Chagas disease (American trypanosomiasis) 6/139 130/7206 0.0394078704545 ko04514 Cell adhesion molecules (CAMs) 6/139 130/7206 0.0394078704545 ko05132 Salmonella infection 5/139 98/7206 0.040514450377