ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	154/976	423/7206	7.38916506896e-35
ko04724	Glutamatergic synapse	72/976	152/7206	1.95370359036e-24
ko05033	Nicotine addiction	37/976	56/7206	1.30913844343e-19
ko04721	Synaptic vesicle cycle	44/976	80/7206	1.4338953352e-18
ko05032	Morphine addiction	52/976	110/7206	6.79819109845e-18
ko04713	Circadian entrainment	58/976	136/7206	3.47283887382e-17
ko04727	GABAergic synapse	51/976	110/7206	4.02740998705e-17
ko04728	Dopaminergic synapse	69/976	185/7206	1.69612675545e-16
ko04725	Cholinergic synapse	60/976	160/7206	1.28854953202e-14
ko04723	Retrograde endocannabinoid signaling	62/976	175/7206	9.69758517998e-14
ko04726	Serotonergic synapse	51/976	137/7206	1.83449645478e-12
ko04911	Insulin secretion	45/976	117/7206	1.03013932984e-11
ko04024	cAMP signaling pathway	79/976	279/7206	4.16041628829e-11
ko04921	Oxytocin signaling pathway	61/976	209/7206	1.80935785157e-09
ko04020	Calcium signaling pathway	72/976	265/7206	2.18375054787e-09
ko05322	Systemic lupus erythematosus	1/976	151/7206	9.90838663387e-09
ko05031	Amphetamine addiction	33/976	91/7206	3.36128179092e-08
ko04742	Taste transduction	25/976	61/7206	9.92226925294e-08
ko04970	Salivary secretion	33/976	95/7206	1.11237064456e-07
ko03010	Ribosome	1/976	129/7206	1.85506039346e-07
ko03040	Spliceosome	2/976	145/7206	2.48032915979e-07
ko04971	Gastric acid secretion	33/976	98/7206	2.57426696561e-07
ko04261	Adrenergic signaling in cardiomyocytes	54/976	205/7206	7.21809073273e-07
ko04966	Collecting duct acid secretion	14/976	26/7206	1.26332851104e-06
ko04720	Long-term potentiation	32/976	99/7206	1.6015761733e-06
ko04925	Aldosterone synthesis and secretion	33/976	105/7206	1.73873864169e-06
ko04120	Ubiquitin mediated proteolysis	3/976	138/7206	6.59026387832e-06
ko05030	Cocaine addiction	24/976	73/7206	1.75036653185e-05
ko04972	Pancreatic secretion	32/976	111/7206	1.82305407006e-05
ko03013	RNA transport	6/976	166/7206	2.67916962294e-05
ko04744	Phototransduction	15/976	36/7206	2.93094006806e-05
ko04730	Long-term depression	25/976	78/7206	3.03179285062e-05
ko05203	Viral carcinogenesis	16/976	277/7206	3.28171117392e-05
ko04070	Phosphatidylinositol signaling system	32/976	112/7206	3.32110011773e-05
ko05110	Vibrio cholerae infection	21/976	63/7206	4.61489985513e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/976	74/7206	9.07656395832e-05
ko04022	cGMP-PKG signaling pathway	50/976	216/7206	0.000104343160584
ko04010	MAPK signaling pathway	68/976	321/7206	0.000112146756984
ko03008	Ribosome biogenesis in eukaryotes	1/976	79/7206	0.00020325391007
ko04514	Cell adhesion molecules (CAMs)	33/976	130/7206	0.000241665941479
ko04745	Phototransduction - fly	14/976	38/7206	0.000260001475897
ko04750	Inflammatory mediator regulation of TRP channels	31/976	122/7206	0.000414390320898
ko04141	Protein processing in endoplasmic reticulum	10/976	184/7206	0.000442336022507
ko05168	Herpes simplex infection	10/976	182/7206	0.000600985771589
ko04014	Ras signaling pathway	58/976	279/7206	0.000647186630929
ko04110	Cell cycle	7/976	145/7206	0.000837480506558
ko04964	Proximal tubule bicarbonate reclamation	11/976	29/7206	0.000892340786177
ko04540	Gap junction	31/976	128/7206	0.00096877723056
ko04710	Circadian rhythm	14/976	43/7206	0.00109524885613
ko05169	Epstein-Barr virus infection	13/976	206/7206	0.0012512641047
ko04360	Axon guidance	49/976	233/7206	0.00125529908513
ko04072	Phospholipase D signaling pathway	43/976	197/7206	0.00139219415786
ko05166	HTLV-I infection	22/976	292/7206	0.00157631944875
ko04621	NOD-like receptor signaling pathway	9/976	157/7206	0.00206855884676
ko05164	Influenza A	10/976	167/7206	0.00268628944467
ko05161	Hepatitis B	11/976	173/7206	0.00330465718919
ko05162	Measles	6/976	120/7206	0.00423974699073
ko04740	Olfactory transduction	20/976	80/7206	0.00486832886156
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/976	59/7206	0.0060421190465
ko04626	Plant-pathogen interaction	7/976	18/7206	0.0066859034498
ko04146	Peroxisome	4/976	89/7206	0.00771591753002
ko00280	Valine, leucine and isoleucine degradation	1/976	54/7206	0.00784925897786
ko04960	Aldosterone-regulated sodium reabsorption	12/976	41/7206	0.00899852716104
ko04612	Antigen processing and presentation	3/976	77/7206	0.010725836208
ko05133	Pertussis	4/976	87/7206	0.0108280157121
ko05205	Proteoglycans in cancer	23/976	271/7206	0.011155475407
ko05016	Huntington's disease	17/976	215/7206	0.0113652010664
ko00562	Inositol phosphate metabolism	21/976	89/7206	0.0114077087914
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/976	92/7206	0.0134165054406
ko04924	Renin secretion	20/976	86/7206	0.0159062784874
ko04260	Cardiac muscle contraction	22/976	98/7206	0.0161493010175
ko03420	Nucleotide excision repair	1/976	46/7206	0.0164787978301
ko05418	Fluid shear stress and atherosclerosis	13/976	173/7206	0.0176690841881
ko04932	Non-alcoholic fatty liver disease (NAFLD)	14/976	182/7206	0.0204986523195
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/976	79/7206	0.0205886865071
ko04711	Circadian rhythm - fly	5/976	13/7206	0.0227003059285
ko04270	Vascular smooth muscle contraction	31/976	154/7206	0.0228360800548
ko03022	Basal transcription factors	1/976	44/7206	0.0246703398587
ko05144	Malaria	1/976	45/7206	0.0255009658919
ko00071	Fatty acid degradation	1/976	45/7206	0.0255009658919
ko04918	Thyroid hormone synthesis	19/976	86/7206	0.0258077189779
ko04657	IL-17 signaling pathway	5/976	87/7206	0.0274035378681
ko05222	Small cell lung cancer	5/976	89/7206	0.0276865852757
ko05416	Viral myocarditis	2/976	55/7206	0.0279258164086
ko05130	Pathogenic Escherichia coli infection	4/976	77/7206	0.0285541294582
ko04550	Signaling pathways regulating pluripotency of stem cells	13/976	165/7206	0.0286666964565
ko04976	Bile secretion	18/976	80/7206	0.0305538511591
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/976	14/7206	0.0314652368307
ko04064	NF-kappa B signaling pathway	6/976	96/7206	0.0346154737299
ko05145	Toxoplasmosis	9/976	126/7206	0.0346894317326
ko04915	Estrogen signaling pathway	26/976	131/7206	0.0389123821983
ko00310	Lysine degradation	4/976	73/7206	0.0391279943978
ko05140	Leishmaniasis	4/976	75/7206	0.0397563659228
ko00680	Methane metabolism	9/976	34/7206	0.0400786403347
ko04622	RIG-I-like receptor signaling pathway	3/976	62/7206	0.0402804623824
ko04350	TGF-beta signaling pathway	7/976	103/7206	0.0420395201177
ko04930	Type II diabetes mellitus	13/976	54/7206	0.0422615516467
ko04510	Focal adhesion	22/976	240/7206	0.043745776297
ko04217	Necroptosis	15/976	178/7206	0.0452748253197
ko05200	Pathways in cancer	52/976	492/7206	0.0475931501083
ko04015	Rap1 signaling pathway	49/976	278/7206	0.0488287307302