ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	167/1041	423/7206	2.07782092346e-39
ko05033	Nicotine addiction	41/1041	56/7206	3.231469871e-23
ko04724	Glutamatergic synapse	71/1041	152/7206	5.89559465613e-22
ko04721	Synaptic vesicle cycle	46/1041	80/7206	2.85821021189e-19
ko05032	Morphine addiction	54/1041	110/7206	3.48529260091e-18
ko04727	GABAergic synapse	53/1041	110/7206	2.05669769308e-17
ko04728	Dopaminergic synapse	72/1041	185/7206	8.75343560434e-17
ko04024	cAMP signaling pathway	93/1041	279/7206	4.15429732189e-16
ko04713	Circadian entrainment	56/1041	136/7206	1.48601796948e-14
ko04725	Cholinergic synapse	62/1041	160/7206	1.66167718736e-14
ko04020	Calcium signaling pathway	84/1041	265/7206	3.61200094227e-13
ko04723	Retrograde endocannabinoid signaling	63/1041	175/7206	5.3611606823e-13
ko04726	Serotonergic synapse	51/1041	137/7206	2.21501706707e-11
ko04921	Oxytocin signaling pathway	67/1041	209/7206	4.62481143646e-11
ko04911	Insulin secretion	43/1041	117/7206	1.34678272273e-09
ko05031	Amphetamine addiction	36/1041	91/7206	3.00592631009e-09
ko04742	Taste transduction	28/1041	61/7206	3.33414597733e-09
ko04744	Phototransduction	20/1041	36/7206	9.60184144196e-09
ko04261	Adrenergic signaling in cardiomyocytes	60/1041	205/7206	2.68432335736e-08
ko05322	Systemic lupus erythematosus	2/1041	151/7206	2.84798028496e-08
ko04966	Collecting duct acid secretion	16/1041	26/7206	4.11036986011e-08
ko03040	Spliceosome	2/1041	145/7206	6.44694910412e-08
ko03010	Ribosome	1/1041	129/7206	7.43175273221e-08
ko05030	Cocaine addiction	28/1041	73/7206	3.70163593489e-07
ko04022	cGMP-PKG signaling pathway	57/1041	216/7206	2.85806458727e-06
ko04970	Salivary secretion	31/1041	95/7206	5.49686801041e-06
ko04720	Long-term potentiation	32/1041	99/7206	7.72663462856e-06
ko04070	Phosphatidylinositol signaling system	34/1041	112/7206	1.5478048666e-05
ko05203	Viral carcinogenesis	17/1041	277/7206	1.62140303583e-05
ko03013	RNA transport	7/1041	166/7206	2.75406066964e-05
ko04925	Aldosterone synthesis and secretion	32/1041	105/7206	3.02183288924e-05
ko04971	Gastric acid secretion	30/1041	98/7206	3.34989196665e-05
ko05168	Herpes simplex infection	9/1041	182/7206	6.22602852363e-05
ko04110	Cell cycle	6/1041	145/7206	0.000103280803083
ko04010	MAPK signaling pathway	71/1041	321/7206	0.000168761420007
ko04710	Circadian rhythm	16/1041	43/7206	0.000181445787831
ko04964	Proximal tubule bicarbonate reclamation	12/1041	29/7206	0.000372335428393
ko04141	Protein processing in endoplasmic reticulum	11/1041	184/7206	0.000406885941815
ko05110	Vibrio cholerae infection	20/1041	63/7206	0.000414722205788
ko04730	Long-term depression	23/1041	78/7206	0.000522360321069
ko04972	Pancreatic secretion	30/1041	111/7206	0.000531472349001
ko05166	HTLV-I infection	23/1041	292/7206	0.000639620307341
ko05014	Amyotrophic lateral sclerosis (ALS)	22/1041	74/7206	0.000652089035894
ko05164	Influenza A	10/1041	167/7206	0.00076892665087
ko04514	Cell adhesion molecules (CAMs)	33/1041	130/7206	0.000913905757512
ko04612	Antigen processing and presentation	2/1041	77/7206	0.000932034623144
ko03008	Ribosome biogenesis in eukaryotes	2/1041	79/7206	0.000984674137109
ko04930	Type II diabetes mellitus	17/1041	54/7206	0.0013065678365
ko04922	Glucagon signaling pathway	32/1041	128/7206	0.00136153641438
ko05162	Measles	6/1041	120/7206	0.00149584722448
ko04330	Notch signaling pathway	1/1041	62/7206	0.001522205095
ko04060	Cytokine-cytokine receptor interaction	13/1041	191/7206	0.00160069954269
ko05169	Epstein-Barr virus infection	15/1041	206/7206	0.00176422070598
ko04745	Phototransduction - fly	13/1041	38/7206	0.00178703927268
ko04260	Cardiac muscle contraction	26/1041	98/7206	0.00199956636726
ko04120	Ubiquitin mediated proteolysis	8/1041	138/7206	0.00204558823878
ko04510	Focal adhesion	19/1041	240/7206	0.00264968333915
ko04350	TGF-beta signaling pathway	5/1041	103/7206	0.00280924515759
ko04923	Regulation of lipolysis in adipocytes	21/1041	77/7206	0.00290776928392
ko05161	Hepatitis B	12/1041	173/7206	0.00295112760999
ko04014	Ras signaling pathway	58/1041	279/7206	0.00308140666121
ko00520	Amino sugar and nucleotide sugar metabolism	1/1041	55/7206	0.00325321227065
ko04072	Phospholipase D signaling pathway	43/1041	197/7206	0.00521701964903
ko04924	Renin secretion	22/1041	86/7206	0.00528953039731
ko04621	NOD-like receptor signaling pathway	11/1041	157/7206	0.00556755954427
ko04976	Bile secretion	21/1041	80/7206	0.0056854111918
ko04750	Inflammatory mediator regulation of TRP channels	29/1041	122/7206	0.00585974448309
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/1041	59/7206	0.00894452642639
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1041	14/7206	0.00952661460098
ko04626	Plant-pathogen interaction	7/1041	18/7206	0.00954871158151
ko04360	Axon guidance	48/1041	233/7206	0.010166954762
ko04214	Apoptosis - fly	3/1041	72/7206	0.0102734986692
ko04740	Olfactory transduction	20/1041	80/7206	0.0103005307701
ko05205	Proteoglycans in cancer	25/1041	271/7206	0.0105793007071
ko00290	Valine, leucine and isoleucine biosynthesis	3/1041	4/7206	0.0107296011746
ko03420	Nucleotide excision repair	1/1041	46/7206	0.0107388987353
ko04540	Gap junction	29/1041	128/7206	0.0108604853878
ko05219	Bladder cancer	1/1041	48/7206	0.0113256168165
ko05200	Pathways in cancer	52/1041	492/7206	0.0114157621194
ko00910	Nitrogen metabolism	7/1041	19/7206	0.0132701936093
ko03022	Basal transcription factors	1/1041	44/7206	0.0161129443609
ko04915	Estrogen signaling pathway	29/1041	131/7206	0.0164897797473
ko00280	Valine, leucine and isoleucine degradation	2/1041	54/7206	0.0188010741012
ko05416	Viral myocarditis	2/1041	55/7206	0.0190653003466
ko00010	Glycolysis / Gluconeogenesis	18/1041	74/7206	0.0198620079325
ko05133	Pertussis	5/1041	87/7206	0.0199908390081
ko05140	Leishmaniasis	4/1041	75/7206	0.0200862855906
ko05414	Dilated cardiomyopathy	25/1041	112/7206	0.0211189476973
ko00562	Inositol phosphate metabolism	21/1041	89/7206	0.021427250447
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/1041	79/7206	0.0226936980702
ko00680	Methane metabolism	10/1041	34/7206	0.0234663595999
ko05131	Shigellosis	5/1041	82/7206	0.0266333607523
ko04622	RIG-I-like receptor signaling pathway	3/1041	62/7206	0.0281649005948
ko05215	Prostate cancer	8/1041	111/7206	0.0285447020763
ko04115	p53 signaling pathway	4/1041	74/7206	0.0287079711515
ko05016	Huntington's disease	20/1041	215/7206	0.0297863601394
ko04371	Apelin signaling pathway	36/1041	177/7206	0.0298317975963
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/1041	92/7206	0.0348858090414
ko03410	Base excision repair	1/1041	38/7206	0.0351660145204
ko04610	Complement and coagulation cascades	5/1041	79/7206	0.036137291112
ko05145	Toxoplasmosis	10/1041	126/7206	0.039648799399
ko04960	Aldosterone-regulated sodium reabsorption	11/1041	41/7206	0.0404129542647
ko04658	Th1 and Th2 cell differentiation	7/1041	96/7206	0.0411161639653
ko04630	Jak-STAT signaling pathway	11/1041	132/7206	0.0449475130439
ko05231	Choline metabolism in cancer	28/1041	134/7206	0.0458933094164