ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	153/823	423/7206	8.88754268536e-44
ko05033	Nicotine addiction	46/823	56/7206	1.67550145536e-34
ko04724	Glutamatergic synapse	77/823	152/7206	1.04541418575e-33
ko04713	Circadian entrainment	60/823	136/7206	2.00658674344e-22
ko05032	Morphine addiction	53/823	110/7206	3.88115470626e-22
ko04727	GABAergic synapse	52/823	110/7206	2.9262305349e-21
ko04728	Dopaminergic synapse	69/823	185/7206	1.32872857932e-20
ko04725	Cholinergic synapse	62/823	160/7206	1.35179789223e-19
ko04723	Retrograde endocannabinoid signaling	64/823	175/7206	1.15586025116e-18
ko04024	cAMP signaling pathway	82/823	279/7206	6.72079191849e-17
ko04721	Synaptic vesicle cycle	37/823	80/7206	4.39600857635e-15
ko04911	Insulin secretion	43/823	117/7206	5.29459423421e-13
ko04744	Phototransduction	22/823	36/7206	1.13404869908e-12
ko04742	Taste transduction	29/823	61/7206	1.77167115727e-12
ko05031	Amphetamine addiction	36/823	91/7206	3.42217391796e-12
ko04726	Serotonergic synapse	46/823	137/7206	3.43514712185e-12
ko04020	Calcium signaling pathway	70/823	265/7206	4.7485061577e-12
ko04921	Oxytocin signaling pathway	58/823	209/7206	4.67415721101e-11
ko04720	Long-term potentiation	35/823	99/7206	2.79375395172e-10
ko04261	Adrenergic signaling in cardiomyocytes	54/823	205/7206	1.88785783626e-09
ko05030	Cocaine addiction	28/823	73/7206	2.07160907401e-09
ko05014	Amyotrophic lateral sclerosis (ALS)	27/823	74/7206	1.4323219441e-08
ko04740	Olfactory transduction	28/823	80/7206	2.23238706577e-08
ko05203	Viral carcinogenesis	8/823	277/7206	2.18278162288e-07
ko04970	Salivary secretion	29/823	95/7206	3.74748138673e-07
ko03040	Spliceosome	1/823	145/7206	8.88729660643e-07
ko04925	Aldosterone synthesis and secretion	30/823	105/7206	1.14661080109e-06
ko04120	Ubiquitin mediated proteolysis	1/823	138/7206	2.00660783065e-06
ko04010	MAPK signaling pathway	65/823	321/7206	2.43571168665e-06
ko04060	Cytokine-cytokine receptor interaction	4/823	191/7206	2.44627739651e-06
ko04971	Gastric acid secretion	28/823	98/7206	2.60304393612e-06
ko05164	Influenza A	3/823	167/7206	5.60424551799e-06
ko04514	Cell adhesion molecules (CAMs)	33/823	130/7206	8.23396183975e-06
ko04022	cGMP-PKG signaling pathway	47/823	216/7206	9.95116224353e-06
ko05168	Herpes simplex infection	5/823	182/7206	2.72187200698e-05
ko04745	Phototransduction - fly	14/823	38/7206	3.98773981584e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/823	79/7206	4.71633814664e-05
ko04260	Cardiac muscle contraction	25/823	98/7206	7.9431126521e-05
ko04360	Axon guidance	47/823	233/7206	8.70331639197e-05
ko04972	Pancreatic secretion	27/823	111/7206	0.000112581911413
ko05322	Systemic lupus erythematosus	4/823	151/7206	0.000136468797474
ko03013	RNA transport	5/823	166/7206	0.000164682739685
ko04730	Long-term depression	21/823	78/7206	0.000192898824688
ko04621	NOD-like receptor signaling pathway	5/823	157/7206	0.000315686534529
ko05169	Epstein-Barr virus infection	9/823	206/7206	0.000509014348925
ko05162	Measles	3/823	120/7206	0.000693139237455
ko04350	TGF-beta signaling pathway	2/823	103/7206	0.000803588150781
ko04072	Phospholipase D signaling pathway	38/823	197/7206	0.000930703986684
ko04610	Complement and coagulation cascades	1/823	79/7206	0.0011584520718
ko03008	Ribosome biogenesis in eukaryotes	1/823	79/7206	0.0011584520718
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/823	182/7206	0.00129568513539
ko05166	HTLV-I infection	17/823	292/7206	0.00131728145906
ko04612	Antigen processing and presentation	1/823	77/7206	0.00173845886854
ko05161	Hepatitis B	8/823	173/7206	0.00236709001302
ko04214	Apoptosis - fly	1/823	72/7206	0.00254276481185
ko04540	Gap junction	26/823	128/7206	0.00294359087048
ko04141	Protein processing in endoplasmic reticulum	9/823	184/7206	0.00308447906022
ko04630	Jak-STAT signaling pathway	5/823	132/7206	0.00331152054848
ko04110	Cell cycle	6/823	145/7206	0.00334746162118
ko04750	Inflammatory mediator regulation of TRP channels	25/823	122/7206	0.00356419905457
ko04930	Type II diabetes mellitus	14/823	54/7206	0.00373595963642
ko04964	Proximal tubule bicarbonate reclamation	9/823	29/7206	0.0038139543473
ko05414	Dilated cardiomyopathy	23/823	112/7206	0.00419327435132
ko05205	Proteoglycans in cancer	17/823	271/7206	0.004654312247
ko04014	Ras signaling pathway	47/823	279/7206	0.00526322348286
ko04924	Renin secretion	19/823	86/7206	0.00532032888358
ko04064	NF-kappa B signaling pathway	3/823	96/7206	0.0056357404757
ko05215	Prostate cancer	4/823	111/7206	0.00612126267776
ko04640	Hematopoietic cell lineage	1/823	64/7206	0.00858540662376
ko05140	Leishmaniasis	2/823	75/7206	0.0101498880508
ko04626	Plant-pathogen interaction	6/823	18/7206	0.0120686448526
ko04140	Autophagy - animal	9/823	164/7206	0.0126022824628
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/823	14/7206	0.015905031289
ko04510	Focal adhesion	16/823	240/7206	0.0171605084235
ko04915	Estrogen signaling pathway	24/823	131/7206	0.0176388524614
ko00280	Valine, leucine and isoleucine degradation	1/823	54/7206	0.0177445095334
ko00480	Glutathione metabolism	1/823	55/7206	0.0177747183181
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/823	59/7206	0.0205893537298
ko04976	Bile secretion	16/823	80/7206	0.0210351972205
ko05016	Huntington's disease	14/823	215/7206	0.0215781830189
ko05034	Alcoholism	39/823	238/7206	0.0219240773091
ko00240	Pyrimidine metabolism	5/823	110/7206	0.0220077361922
ko03018	RNA degradation	3/823	84/7206	0.0228334753932
ko04070	Phosphatidylinositol signaling system	21/823	112/7206	0.0231184454761
ko04966	Collecting duct acid secretion	7/823	26/7206	0.0231877545917
ko05410	Hypertrophic cardiomyopathy (HCM)	19/823	100/7206	0.0250074322661
ko04150	mTOR signaling pathway	12/823	184/7206	0.0339343258208
ko04142	Lysosome	9/823	151/7206	0.0372005217821
ko00270	Cysteine and methionine metabolism	1/823	47/7206	0.0380784174933
ko05200	Pathways in cancer	42/823	492/7206	0.0394526927841
ko04657	IL-17 signaling pathway	4/823	87/7206	0.0413326264965
ko00330	Arginine and proline metabolism	2/823	61/7206	0.0420310294909
ko04146	Peroxisome	4/823	89/7206	0.0420424144663
ko04330	Notch signaling pathway	2/823	62/7206	0.042452470022
ko00561	Glycerolipid metabolism	2/823	63/7206	0.0433052354029
ko01524	Platinum drug resistance	3/823	76/7206	0.0434900825789