ko pathway ratio_in_study ratio_in_pop p_value ko00120 Primary bile acid biosynthesis 9/281 20/7206 2.11423404024e-08 ko00643 Styrene degradation 3/281 4/7206 0.000227965884279 ko00592 alpha-Linolenic acid metabolism 5/281 19/7206 0.000644721302448 ko00140 Steroid hormone biosynthesis 7/281 41/7206 0.000914611251191 ko04064 NF-kappa B signaling pathway 11/281 96/7206 0.00120378020257 ko00350 Tyrosine metabolism 6/281 33/7206 0.00151680948969 ko03320 PPAR signaling pathway 8/281 69/7206 0.00513008011126 ko00983 Drug metabolism - other enzymes 6/281 42/7206 0.005357737541 ko00620 Pyruvate metabolism 6/281 46/7206 0.00840304119086 ko04621 NOD-like receptor signaling pathway 13/281 157/7206 0.00995782683793 ko05204 Chemical carcinogenesis 6/281 48/7206 0.0103192704005 ko00982 Drug metabolism - cytochrome P450 5/281 37/7206 0.0136375883489 ko00362 Benzoate degradation 2/281 6/7206 0.020483706197 ko04925 Aldosterone synthesis and secretion 9/281 105/7206 0.0209614578177 ko04060 Cytokine-cytokine receptor interaction 14/281 191/7206 0.0209854047146 ko00830 Retinol metabolism 5/281 42/7206 0.0227467974518 ko00051 Fructose and mannose metabolism 5/281 42/7206 0.0227467974518 ko04710 Circadian rhythm 5/281 43/7206 0.0249466829294 ko05120 Epithelial cell signaling in Helicobacter pylori infection 8/281 92/7206 0.0265939851274 ko04660 T cell receptor signaling pathway 10/281 124/7206 0.0295179170637 ko00071 Fatty acid degradation 5/281 45/7206 0.029745144621 ko04932 Non-alcoholic fatty liver disease (NAFLD) 13/281 182/7206 0.0309092979054 ko04626 Plant-pathogen interaction 3/281 18/7206 0.0310126985816 ko04136 Autophagy - other 4/281 31/7206 0.0310958744763 ko05322 Systemic lupus erythematosus 1/281 151/7206 0.0314350525264 ko00190 Oxidative phosphorylation 10/281 127/7206 0.0323116949021 ko00030 Pentose phosphate pathway 4/281 32/7206 0.0344841603475 ko00270 Cysteine and methionine metabolism 5/281 47/7206 0.0350885291093 ko00401 Novobiocin biosynthesis 1/281 1/7206 0.0389952817097 ko05164 Influenza A 12/281 167/7206 0.0392841262034 ko05131 Shigellosis 7/281 82/7206 0.0401820447868 ko04137 Mitophagy - animal 7/281 82/7206 0.0401820447868 ko04380 Osteoclast differentiation 10/281 134/7206 0.0407138543965 ko00380 Tryptophan metabolism 5/281 50/7206 0.044152001699 ko00100 Steroid biosynthesis 3/281 21/7206 0.0464154429724 ko03040 Spliceosome 1/281 145/7206 0.0465206344196 ko04110 Cell cycle 1/281 145/7206 0.0465206344196 ko05206 MicroRNAs in cancer 2/281 177/7206 0.0489005054577