ko pathway ratio_in_study ratio_in_pop p_value ko04260 Cardiac muscle contraction 23/126 98/7206 2.41213782865e-20 ko05410 Hypertrophic cardiomyopathy (HCM) 23/126 100/7206 3.96839174903e-20 ko05414 Dilated cardiomyopathy 22/126 112/7206 1.07684308741e-17 ko04261 Adrenergic signaling in cardiomyocytes 25/126 205/7206 6.94933166637e-15 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 12/126 79/7206 9.14989242953e-09 ko05416 Viral myocarditis 10/126 55/7206 2.80488939665e-08 ko04020 Calcium signaling pathway 16/126 265/7206 1.33780516767e-05 ko04510 Focal adhesion 15/126 240/7206 1.68954058744e-05 ko04512 ECM-receptor interaction 8/126 79/7206 6.45062291093e-05 ko04921 Oxytocin signaling pathway 13/126 209/7206 6.72120181686e-05 ko04974 Protein digestion and absorption 8/126 96/7206 0.000255876873632 ko00010 Glycolysis / Gluconeogenesis 6/126 74/7206 0.00177925145708 ko00030 Pentose phosphate pathway 4/126 32/7206 0.00219362337675 ko00680 Methane metabolism 4/126 34/7206 0.00275390650353 ko04022 cGMP-PKG signaling pathway 10/126 216/7206 0.00442040623142 ko01200 Carbon metabolism 7/126 128/7206 0.0069628516279 ko00710 Carbon fixation in photosynthetic organisms 3/126 27/7206 0.0112403674076 ko04010 MAPK signaling pathway 12/126 321/7206 0.0132006011357 ko01230 Biosynthesis of amino acids 5/126 85/7206 0.0162697824892 ko00250 Alanine, aspartate and glutamate metabolism 3/126 38/7206 0.0282256462585 ko04371 Apelin signaling pathway 7/126 177/7206 0.035165722377 ko00051 Fructose and mannose metabolism 3/126 42/7206 0.0365359814391 ko04151 PI3K-Akt signaling pathway 12/126 390/7206 0.0466122186799