ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	150/756	423/7206	1.55848805688e-46
ko05033	Nicotine addiction	42/756	56/7206	3.66077691248e-30
ko04724	Glutamatergic synapse	63/756	152/7206	9.535899061e-24
ko04728	Dopaminergic synapse	62/756	185/7206	8.2531173957e-18
ko04727	GABAergic synapse	43/756	110/7206	1.9664897868e-15
ko04713	Circadian entrainment	48/756	136/7206	4.9754195889e-15
ko05032	Morphine addiction	42/756	110/7206	1.12071065499e-14
ko04721	Synaptic vesicle cycle	35/756	80/7206	1.47260584289e-14
ko04723	Retrograde endocannabinoid signaling	53/756	175/7206	2.4857659768e-13
ko04024	cAMP signaling pathway	68/756	279/7206	1.02492224783e-11
ko04725	Cholinergic synapse	47/756	160/7206	1.96189505956e-11
ko04742	Taste transduction	25/756	61/7206	5.00795854409e-10
ko04911	Insulin secretion	36/756	117/7206	1.15353592032e-09
ko04726	Serotonergic synapse	39/756	137/7206	2.88354184914e-09
ko05030	Cocaine addiction	26/756	73/7206	7.99732516941e-09
ko05031	Amphetamine addiction	29/756	91/7206	2.01652599022e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	25/756	74/7206	5.24888520316e-08
ko04261	Adrenergic signaling in cardiomyocytes	48/756	205/7206	8.00215013313e-08
ko04010	MAPK signaling pathway	64/756	321/7206	3.07825671132e-07
ko04020	Calcium signaling pathway	55/756	265/7206	5.670193268e-07
ko05203	Viral carcinogenesis	7/756	277/7206	6.05075918457e-07
ko04970	Salivary secretion	27/756	95/7206	8.36148395686e-07
ko04921	Oxytocin signaling pathway	45/756	209/7206	1.78432763032e-06
ko03040	Spliceosome	1/756	145/7206	3.1575564855e-06
ko04514	Cell adhesion molecules (CAMs)	32/756	130/7206	3.22549222119e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/756	79/7206	1.24137494837e-05
ko04360	Axon guidance	46/756	233/7206	1.75726358539e-05
ko04720	Long-term potentiation	25/756	99/7206	2.09996048672e-05
ko05168	Herpes simplex infection	4/756	182/7206	2.38713151169e-05
ko04730	Long-term depression	21/756	78/7206	3.41151322297e-05
ko04060	Cytokine-cytokine receptor interaction	5/756	191/7206	5.97738164851e-05
ko04964	Proximal tubule bicarbonate reclamation	11/756	29/7206	9.22057572697e-05
ko05164	Influenza A	4/756	167/7206	0.000100759144942
ko04260	Cardiac muscle contraction	23/756	98/7206	0.000167831546608
ko04120	Ubiquitin mediated proteolysis	3/756	138/7206	0.000352682435786
ko05205	Proteoglycans in cancer	12/756	271/7206	0.000367232790667
ko05322	Systemic lupus erythematosus	4/756	151/7206	0.000413635307532
ko03013	RNA transport	5/756	166/7206	0.000466287970424
ko04972	Pancreatic secretion	24/756	111/7206	0.000467690789047
ko04971	Gastric acid secretion	22/756	98/7206	0.000631312551624
ko04621	NOD-like receptor signaling pathway	5/756	157/7206	0.00091319368987
ko04014	Ras signaling pathway	47/756	279/7206	0.000924126466534
ko04140	Autophagy - animal	6/756	164/7206	0.0018309955888
ko03018	RNA degradation	1/756	84/7206	0.00183530424569
ko04978	Mineral absorption	11/756	40/7206	0.00209772911911
ko03008	Ribosome biogenesis in eukaryotes	1/756	79/7206	0.00266334995251
ko01200	Carbon metabolism	4/756	128/7206	0.00324040194535
ko04141	Protein processing in endoplasmic reticulum	8/756	184/7206	0.00332041483549
ko04924	Renin secretion	18/756	86/7206	0.00381474030802
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/756	59/7206	0.00397572868444
ko04612	Antigen processing and presentation	1/756	77/7206	0.00407076634574
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/756	182/7206	0.00448688950835
ko04022	cGMP-PKG signaling pathway	36/756	216/7206	0.00455714275977
ko04976	Bile secretion	17/756	80/7206	0.00473489421777
ko04540	Gap junction	24/756	128/7206	0.00499632667891
ko05169	Epstein-Barr virus infection	10/756	206/7206	0.00531843835377
ko04214	Apoptosis - fly	1/756	72/7206	0.00583028276461
ko05166	HTLV-I infection	17/756	292/7206	0.00612656813256
ko05162	Measles	4/756	120/7206	0.00629372709441
ko04142	Lysosome	6/756	151/7206	0.0066123999782
ko04630	Jak-STAT signaling pathway	5/756	132/7206	0.00901749905459
ko04925	Aldosterone synthesis and secretion	20/756	105/7206	0.00904346948655
ko04015	Rap1 signaling pathway	43/756	278/7206	0.00906648501295
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/756	14/7206	0.0111977077958
ko00561	Glycerolipid metabolism	1/756	63/7206	0.0124682268122
ko04640	Hematopoietic cell lineage	1/756	64/7206	0.0125385464286
ko04217	Necroptosis	9/756	178/7206	0.0129652545947
ko04966	Collecting duct acid secretion	7/756	26/7206	0.0150521796121
ko04974	Protein digestion and absorption	18/756	96/7206	0.0171012292673
ko00240	Pyrimidine metabolism	4/756	110/7206	0.017171081688
ko05414	Dilated cardiomyopathy	20/756	112/7206	0.018185576257
ko04072	Phospholipase D signaling pathway	31/756	197/7206	0.0183471212439
ko00330	Arginine and proline metabolism	1/756	61/7206	0.0186552053794
ko05410	Hypertrophic cardiomyopathy (HCM)	18/756	100/7206	0.0202007836082
ko04150	mTOR signaling pathway	10/756	184/7206	0.0202226628778
ko00010	Glycolysis / Gluconeogenesis	2/756	74/7206	0.0213795656158
ko05140	Leishmaniasis	2/756	75/7206	0.0215056572998
ko04146	Peroxisome	3/756	89/7206	0.0226661271669
ko05161	Hepatitis B	9/756	173/7206	0.0227203133915
ko04930	Type II diabetes mellitus	11/756	54/7206	0.0249060836674
ko04740	Olfactory transduction	15/756	80/7206	0.0252453440038
ko00480	Glutathione metabolism	1/756	55/7206	0.0267367202354
ko04915	Estrogen signaling pathway	22/756	131/7206	0.029253156976
ko00310	Lysine degradation	2/756	73/7206	0.03169803149
ko04973	Carbohydrate digestion and absorption	9/756	42/7206	0.0368454617751
ko00590	Arachidonic acid metabolism	1/756	52/7206	0.0391150068999
ko04064	NF-kappa B signaling pathway	4/756	96/7206	0.0425654992957
ko04138	Autophagy - yeast	3/756	81/7206	0.043625482278
ko04137	Mitophagy - animal	3/756	82/7206	0.0440125459487
ko03320	PPAR signaling pathway	2/756	69/7206	0.0447652896951
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	6/756	26/7206	0.0483643294357