ko pathway ratio_in_study ratio_in_pop p_value ko05215 Prostate cancer 8/35 111/7206 4.09556271937e-08 ko04910 Insulin signaling pathway 7/35 172/7206 1.49426651757e-05 ko04919 Thyroid hormone signaling pathway 6/35 143/7206 5.55328754877e-05 ko04068 FoxO signaling pathway 6/35 167/7206 0.000131599972441 ko01521 EGFR tyrosine kinase inhibitor resistance 5/35 106/7206 0.000143159002654 ko05206 MicroRNAs in cancer 6/35 177/7206 0.000181100872356 ko05221 Acute myeloid leukemia 4/35 63/7206 0.000226721403775 ko04066 HIF-1 signaling pathway 5/35 123/7206 0.000287684681648 ko05200 Pathways in cancer 9/35 492/7206 0.000425866737538 ko05231 Choline metabolism in cancer 5/35 134/7206 0.000427802056858 ko04931 Insulin resistance 5/35 137/7206 0.000473706212228 ko05212 Pancreatic cancer 4/35 83/7206 0.000652912361905 ko05220 Chronic myeloid leukemia 4/35 85/7206 0.000714480394595 ko04662 B cell receptor signaling pathway 4/35 88/7206 0.000814400937617 ko04152 AMPK signaling pathway 5/35 161/7206 0.000987528464939 ko05211 Renal cell carcinoma 4/35 96/7206 0.00112869756103 ko04932 Non-alcoholic fatty liver disease (NAFLD) 5/35 182/7206 0.00170676330324 ko04014 Ras signaling pathway 6/35 279/7206 0.002008131267 ko04151 PI3K-Akt signaling pathway 7/35 390/7206 0.00231772434209 ko04072 Phospholipase D signaling pathway 5/35 197/7206 0.00241712821485 ko04668 TNF signaling pathway 4/35 120/7206 0.00257011754827 ko04211 Longevity regulating pathway 4/35 123/7206 0.00281134707334 ko04660 T cell receptor signaling pathway 4/35 124/7206 0.00289510097791 ko05169 Epstein-Barr virus infection 5/35 206/7206 0.0029353940254 ko05213 Endometrial cancer 3/35 62/7206 0.00326326883963 ko05223 Non-small cell lung cancer 3/35 66/7206 0.003896382835 ko04933 AGE-RAGE signaling pathway in diabetic complications 4/35 135/7206 0.00393240052684 ko05160 Hepatitis C 4/35 153/7206 0.00613174216653 ko05214 Glioma 3/35 79/7206 0.0064498772079 ko05230 Central carbon metabolism in cancer 3/35 81/7206 0.00691304393869 ko04137 Mitophagy - animal 3/35 82/7206 0.00715188403078 ko04722 Neurotrophin signaling pathway 4/35 160/7206 0.00717190233494 ko04140 Autophagy - animal 4/35 164/7206 0.00781592439659 ko05164 Influenza A 4/35 167/7206 0.00832332535005 ko04917 Prolactin signaling pathway 3/35 87/7206 0.00841963119875 ko04657 IL-17 signaling pathway 3/35 87/7206 0.00841963119875 ko04920 Adipocytokine signaling pathway 3/35 89/7206 0.00896147852119 ko05222 Small cell lung cancer 3/35 89/7206 0.00896147852119 ko01523 Antifolate resistance 2/35 30/7206 0.00915498213026 ko05418 Fluid shear stress and atherosclerosis 4/35 173/7206 0.00940241619583 ko05161 Hepatitis B 4/35 173/7206 0.00940241619583 ko05224 Breast cancer 4/35 174/7206 0.00959075213351 ko00073 Cutin, suberine and wax biosynthesis 1/35 2/7206 0.00969120689965 ko04218 Cellular senescence 4/35 177/7206 0.0101705661581 ko04024 cAMP signaling pathway 5/35 279/7206 0.0105082317675 ko04210 Apoptosis 4/35 180/7206 0.0107728508697 ko04064 NF-kappa B signaling pathway 3/35 96/7206 0.0110173252126 ko04150 mTOR signaling pathway 4/35 184/7206 0.0116114176318 ko04620 Toll-like receptor signaling pathway 3/35 100/7206 0.012305102999 ko05202 Transcriptional misregulation in cancer 4/35 188/7206 0.0124912669898 ko05166 HTLV-I infection 5/35 292/7206 0.0126319739769 ko05167 Kaposi's sarcoma-associated herpesvirus infection 4/35 191/7206 0.0131786811942 ko04012 ErbB signaling pathway 3/35 109/7206 0.0155088082863 ko04062 Chemokine signaling pathway 4/35 201/7206 0.0156444036563 ko04070 Phosphatidylinositol signaling system 3/35 112/7206 0.0166720325746 ko04623 Cytosolic DNA-sensing pathway 2/35 41/7206 0.0166920083628 ko04010 MAPK signaling pathway 5/35 321/7206 0.0183914404743 ko05162 Measles 3/35 120/7206 0.0200094614093 ko04215 Apoptosis - multiple species 2/35 47/7206 0.0216095494006 ko01522 Endocrine resistance 3/35 124/7206 0.0218073036834 ko05145 Toxoplasmosis 3/35 126/7206 0.0227386108439 ko04922 Glucagon signaling pathway 3/35 128/7206 0.0236915300093 ko05142 Chagas disease (American trypanosomiasis) 3/35 130/7206 0.0246660689384 ko04630 Jak-STAT signaling pathway 3/35 132/7206 0.0256622289874 ko04380 Osteoclast differentiation 3/35 134/7206 0.0266800052602 ko04510 Focal adhesion 4/35 240/7206 0.0279722213144 ko04120 Ubiquitin mediated proteolysis 3/35 138/7206 0.0287803565115 ko04330 Notch signaling pathway 2/35 62/7206 0.0361315944182 ko04622 RIG-I-like receptor signaling pathway 2/35 62/7206 0.0361315944182 ko04621 NOD-like receptor signaling pathway 3/35 157/7206 0.0399297065482 ko05205 Proteoglycans in cancer 4/35 271/7206 0.041036347253 ko05203 Viral carcinogenesis 4/35 277/7206 0.0439097081123