ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	136/707	423/7206	5.59532053008e-40
ko04724	Glutamatergic synapse	78/707	152/7206	1.66323280434e-39
ko05033	Nicotine addiction	44/707	56/7206	2.24835057227e-34
ko04727	GABAergic synapse	55/707	110/7206	2.78048093206e-27
ko05032	Morphine addiction	54/707	110/7206	2.70623857366e-26
ko04728	Dopaminergic synapse	68/707	185/7206	1.05857261404e-23
ko04723	Retrograde endocannabinoid signaling	65/707	175/7206	5.56543101564e-23
ko04713	Circadian entrainment	56/707	136/7206	1.75727999156e-22
ko04725	Cholinergic synapse	53/707	160/7206	2.17377761401e-16
ko04024	cAMP signaling pathway	74/707	279/7206	2.4646733322e-16
ko04744	Phototransduction	23/707	36/7206	3.1010411448e-15
ko04726	Serotonergic synapse	44/707	137/7206	2.91843400365e-13
ko04742	Taste transduction	28/707	61/7206	2.92253118226e-13
ko04721	Synaptic vesicle cycle	32/707	80/7206	6.31596180203e-13
ko04911	Insulin secretion	39/707	117/7206	1.81052945917e-12
ko04720	Long-term potentiation	35/707	99/7206	3.69534458777e-12
ko04020	Calcium signaling pathway	64/707	265/7206	3.90857714794e-12
ko05031	Amphetamine addiction	33/707	91/7206	6.90177934539e-12
ko04921	Oxytocin signaling pathway	53/707	209/7206	3.58909646975e-11
ko05030	Cocaine addiction	27/707	73/7206	3.46010572459e-10
ko04261	Adrenergic signaling in cardiomyocytes	49/707	205/7206	2.28644460336e-09
ko05203	Viral carcinogenesis	4/707	277/7206	2.15144919671e-08
ko04060	Cytokine-cytokine receptor interaction	1/707	191/7206	8.71072361181e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	23/707	74/7206	2.94115677945e-07
ko04925	Aldosterone synthesis and secretion	28/707	105/7206	5.52359962984e-07
ko04010	MAPK signaling pathway	59/707	321/7206	1.75997717018e-06
ko03040	Spliceosome	1/707	145/7206	7.35845996214e-06
ko04970	Salivary secretion	24/707	95/7206	9.84276042201e-06
ko04072	Phospholipase D signaling pathway	39/707	197/7206	1.52764981958e-05
ko04514	Cell adhesion molecules (CAMs)	29/707	130/7206	1.80100969591e-05
ko04740	Olfactory transduction	21/707	80/7206	1.87492837611e-05
ko05164	Influenza A	3/707	167/7206	5.81538746714e-05
ko04022	cGMP-PKG signaling pathway	40/707	216/7206	6.31026254836e-05
ko05168	Herpes simplex infection	4/707	182/7206	7.38928422087e-05
ko04730	Long-term depression	19/707	78/7206	0.000139211566734
ko05205	Proteoglycans in cancer	10/707	271/7206	0.000161586232877
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/707	79/7206	0.000166827652582
ko05169	Epstein-Barr virus infection	6/707	206/7206	0.000193744632649
ko04110	Cell cycle	3/707	145/7206	0.000359827255368
ko04915	Estrogen signaling pathway	26/707	131/7206	0.000483632540435
ko04972	Pancreatic secretion	23/707	111/7206	0.000517782685584
ko04745	Phototransduction - fly	11/707	38/7206	0.00075744986041
ko05162	Measles	2/707	120/7206	0.000888706106182
ko05322	Systemic lupus erythematosus	4/707	151/7206	0.00123895377952
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/707	182/7206	0.00140021149408
ko04260	Cardiac muscle contraction	20/707	98/7206	0.0015635047876
ko04971	Gastric acid secretion	20/707	98/7206	0.0015635047876
ko04070	Phosphatidylinositol signaling system	22/707	112/7206	0.00187728503885
ko05414	Dilated cardiomyopathy	22/707	112/7206	0.00187728503885
ko05034	Alcoholism	38/707	238/7206	0.00253508692539
ko04120	Ubiquitin mediated proteolysis	4/707	138/7206	0.00338718890711
ko03013	RNA transport	6/707	166/7206	0.00353998291731
ko04630	Jak-STAT signaling pathway	4/707	132/7206	0.00463390605327
ko04550	Signaling pathways regulating pluripotency of stem cells	6/707	165/7206	0.00492482527819
ko04750	Inflammatory mediator regulation of TRP channels	22/707	122/7206	0.00496186537014
ko04360	Axon guidance	36/707	233/7206	0.00501665651045
ko04924	Renin secretion	17/707	86/7206	0.00503083922385
ko04612	Antigen processing and presentation	1/707	77/7206	0.00600074749825
ko05215	Prostate cancer	3/707	111/7206	0.00602379557211
ko03008	Ribosome biogenesis in eukaryotes	1/707	79/7206	0.00633318572164
ko04014	Ras signaling pathway	41/707	279/7206	0.00742115921482
ko04150	mTOR signaling pathway	8/707	184/7206	0.00812215627424
ko04141	Protein processing in endoplasmic reticulum	8/707	184/7206	0.00812215627424
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/707	14/7206	0.00844964280147
ko04621	NOD-like receptor signaling pathway	6/707	157/7206	0.00914988486174
ko04371	Apelin signaling pathway	28/707	177/7206	0.0100348002207
ko05010	Alzheimer's disease	31/707	202/7206	0.0112153799443
ko04140	Autophagy - animal	7/707	164/7206	0.0114189643439
ko04540	Gap junction	21/707	128/7206	0.0160080425573
ko04930	Type II diabetes mellitus	11/707	54/7206	0.0178940948653
ko05161	Hepatitis B	8/707	173/7206	0.0189694192639
ko04510	Focal adhesion	13/707	240/7206	0.0197609619276
ko05131	Shigellosis	2/707	82/7206	0.0226433563689
ko00240	Pyrimidine metabolism	4/707	110/7206	0.0231682737392
ko04064	NF-kappa B signaling pathway	3/707	96/7206	0.0232670272354
ko05410	Hypertrophic cardiomyopathy (HCM)	17/707	100/7206	0.0255127324382
ko05231	Choline metabolism in cancer	21/707	134/7206	0.0272874460403
ko04330	Notch signaling pathway	1/707	62/7206	0.0284658527684
ko04062	Chemokine signaling pathway	29/707	201/7206	0.0302293089789
ko05140	Leishmaniasis	2/707	75/7206	0.0309378492764
ko05130	Pathogenic Escherichia coli infection	2/707	77/7206	0.0315629537376
ko05166	HTLV-I infection	18/707	292/7206	0.0342519198584
ko04966	Collecting duct acid secretion	6/707	26/7206	0.0364906885986
ko05416	Viral myocarditis	1/707	55/7206	0.0396997639553
ko05321	Inflammatory bowel disease (IBD)	1/707	56/7206	0.0399483040168
ko04214	Apoptosis - fly	2/707	72/7206	0.0440891964972
ko00310	Lysine degradation	2/707	73/7206	0.0447568773992
ko04146	Peroxisome	3/707	89/7206	0.0456312694887