ko pathway ratio_in_study ratio_in_pop p_value ko00190 Oxidative phosphorylation 17/67 127/7206 8.25054279313e-16 ko01200 Carbon metabolism 17/67 128/7206 9.45087705568e-16 ko05012 Parkinson's disease 18/67 155/7206 1.36112598533e-15 ko05010 Alzheimer's disease 19/67 202/7206 1.01871252097e-14 ko05016 Huntington's disease 18/67 215/7206 4.44376946511e-13 ko00020 Citrate cycle (TCA cycle) 9/67 35/7206 1.73900114182e-11 ko00010 Glycolysis / Gluconeogenesis 10/67 74/7206 1.08407081268e-09 ko00710 Carbon fixation in photosynthetic organisms 6/67 27/7206 1.30629029403e-07 ko04932 Non-alcoholic fatty liver disease (NAFLD) 11/67 182/7206 7.40300473815e-07 ko01230 Biosynthesis of amino acids 8/67 85/7206 9.94511791364e-07 ko00620 Pyruvate metabolism 6/67 46/7206 3.59955060098e-06 ko04723 Retrograde endocannabinoid signaling 9/67 175/7206 3.04536757931e-05 ko00030 Pentose phosphate pathway 4/67 32/7206 0.000201804663489 ko00500 Starch and sucrose metabolism 4/67 35/7206 0.000287747202942 ko05230 Central carbon metabolism in cancer 5/67 81/7206 0.000887141347324 ko04922 Glucagon signaling pathway 6/67 128/7206 0.00114895997949 ko04260 Cardiac muscle contraction 5/67 98/7206 0.00208273180352 ko05410 Hypertrophic cardiomyopathy (HCM) 5/67 100/7206 0.00227627864966 ko05414 Dilated cardiomyopathy 5/67 112/7206 0.0037238265706 ko00680 Methane metabolism 3/67 34/7206 0.00374172702223 ko00630 Glyoxylate and dicarboxylate metabolism 3/67 38/7206 0.00513729777879 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 4/67 79/7206 0.0060814494722 ko00051 Fructose and mannose metabolism 3/67 42/7206 0.00680886647392 ko00270 Cysteine and methionine metabolism 3/67 47/7206 0.00930556290064 ko00720 Carbon fixation pathways in prokaryotes 2/67 17/7206 0.0105854008502 ko01210 2-Oxocarboxylic acid metabolism 2/67 20/7206 0.0145259579874 ko02026 Biofilm formation - Escherichia coli 1/67 3/7206 0.0276386783599 ko00230 Purine metabolism 5/67 194/7206 0.0337902699522 ko04020 Calcium signaling pathway 6/67 265/7206 0.0358838073683 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 1/67 4/7206 0.0366832720781 ko00052 Galactose metabolism 2/67 33/7206 0.0373687993261 ko04921 Oxytocin signaling pathway 5/67 209/7206 0.0443045743298 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 1/67 5/7206 0.045644980044 ko00250 Alanine, aspartate and glutamate metabolism 2/67 38/7206 0.0483082148472