ko pathway ratio_in_study ratio_in_pop p_value ko04916 Melanogenesis 16/153 142/7206 4.23827690996e-08 ko05205 Proteoglycans in cancer 18/153 271/7206 1.54502321815e-05 ko05224 Breast cancer 14/153 174/7206 1.74836581225e-05 ko05200 Pathways in cancer 24/153 492/7206 0.000114639383878 ko04550 Signaling pathways regulating pluripotency of stem cells 12/153 165/7206 0.000187898905525 ko04668 TNF signaling pathway 10/153 120/7206 0.000217847973121 ko05206 MicroRNAs in cancer 12/153 177/7206 0.000360675996427 ko04360 Axon guidance 14/153 233/7206 0.000406924476694 ko05219 Bladder cancer 6/153 48/7206 0.000488035821772 ko05215 Prostate cancer 9/153 111/7206 0.000553258471781 ko05217 Basal cell carcinoma 7/153 68/7206 0.000555423632685 ko04390 Hippo signaling pathway 12/153 188/7206 0.000622554146238 ko04060 Cytokine-cytokine receptor interaction 12/153 191/7206 0.000716881959282 ko04014 Ras signaling pathway 15/153 279/7206 0.000815793190915 ko04912 GnRH signaling pathway 9/153 122/7206 0.00109572445813 ko04962 Vasopressin-regulated water reabsorption 6/153 58/7206 0.00135236261573 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 7/153 79/7206 0.00136747771841 ko04931 Insulin resistance 9/153 137/7206 0.00245864802588 ko04072 Phospholipase D signaling pathway 11/153 197/7206 0.00304804216497 ko00533 Glycosaminoglycan biosynthesis - keratan sulfate 3/153 15/7206 0.00354013659827 ko04658 Th1 and Th2 cell differentiation 7/153 96/7206 0.00416869619517 ko05160 Hepatitis C 9/153 153/7206 0.00513382960183 ko04151 PI3K-Akt signaling pathway 17/153 390/7206 0.0054364599177 ko04144 Endocytosis 15/153 342/7206 0.00641020442051 ko04915 Estrogen signaling pathway 8/153 131/7206 0.00657528542284 ko05212 Pancreatic cancer 6/153 83/7206 0.00818045094858 ko04012 ErbB signaling pathway 7/153 109/7206 0.00829772329119 ko04015 Rap1 signaling pathway 13/153 278/7206 0.00831791224114 ko04080 Neuroactive ligand-receptor interaction 2/153 423/7206 0.00856966942934 ko04530 Tight junction 11/153 228/7206 0.00903350791788 ko04918 Thyroid hormone synthesis 6/153 86/7206 0.00967657890047 ko04657 IL-17 signaling pathway 6/153 87/7206 0.0102160217979 ko05221 Acute myeloid leukemia 5/153 63/7206 0.0105653564622 ko05161 Hepatitis B 9/153 173/7206 0.0111648787144 ko04310 Wnt signaling pathway 9/153 181/7206 0.014683621284 ko04064 NF-kappa B signaling pathway 6/153 96/7206 0.0160684947229 ko04660 T cell receptor signaling pathway 7/153 124/7206 0.0161337285757 ko01522 Endocrine resistance 7/153 124/7206 0.0161337285757 ko04150 mTOR signaling pathway 9/153 184/7206 0.0161948267803 ko04024 cAMP signaling pathway 12/153 279/7206 0.0175524880475 ko05146 Amoebiasis 6/153 99/7206 0.0184490163825 ko05030 Cocaine addiction 5/153 73/7206 0.0190879750787 ko04725 Cholinergic synapse 8/153 160/7206 0.0203156930066 ko00540 Lipopolysaccharide biosynthesis 1/153 1/7206 0.0212323064114 ko00944 Flavone and flavonol biosynthesis 1/153 1/7206 0.0212323064114 ko04071 Sphingolipid signaling pathway 8/153 162/7206 0.0217115226168 ko00460 Cyanoamino acid metabolism 2/153 11/7206 0.0217239319138 ko04520 Adherens junction 6/153 103/7206 0.0219845583563 ko00512 Mucin type O-glycan biosynthesis 3/153 29/7206 0.0228994971417 ko04925 Aldosterone synthesis and secretion 6/153 105/7206 0.023913233726 ko01521 EGFR tyrosine kinase inhibitor resistance 6/153 106/7206 0.0249188846805 ko04011 MAPK signaling pathway - yeast 4/153 53/7206 0.025590361249 ko04320 Dorso-ventral axis formation 3/153 31/7206 0.0273199458664 ko05230 Central carbon metabolism in cancer 5/153 81/7206 0.0284864303726 ko05131 Shigellosis 5/153 82/7206 0.0298348323232 ko05166 HTLV-I infection 12/153 292/7206 0.0338214207302 ko05220 Chronic myeloid leukemia 5/153 85/7206 0.0341193434968 ko00430 Taurine and hypotaurine metabolism 2/153 14/7206 0.0344822315465 ko04961 Endocrine and other factor-regulated calcium reabsorption 4/153 59/7206 0.0361083079761 ko04911 Insulin secretion 6/153 117/7206 0.0378817681263 ko04662 B cell receptor signaling pathway 5/153 88/7206 0.0387681064577 ko04261 Adrenergic signaling in cardiomyocytes 9/153 205/7206 0.0416533270841 ko00073 Cutin, suberine and wax biosynthesis 1/153 2/7206 0.0420166863036 ko04622 RIG-I-like receptor signaling pathway 4/153 62/7206 0.0421761183663 ko04666 Fc gamma R-mediated phagocytosis 6/153 122/7206 0.044976386243 ko05120 Epithelial cell signaling in Helicobacter pylori infection 5/153 92/7206 0.0455422555727