ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	185/1209	423/7206	1.42073428039e-41
ko04724	Glutamatergic synapse	85/1209	152/7206	1.43130519734e-28
ko05033	Nicotine addiction	45/1209	56/7206	1.43892912593e-25
ko05032	Morphine addiction	65/1209	110/7206	6.54982710824e-24
ko04727	GABAergic synapse	61/1209	110/7206	1.55672391418e-20
ko04713	Circadian entrainment	69/1209	136/7206	3.5915771148e-20
ko04721	Synaptic vesicle cycle	50/1209	80/7206	3.6101197567e-20
ko04728	Dopaminergic synapse	82/1209	185/7206	5.04798127526e-19
ko04024	cAMP signaling pathway	106/1209	279/7206	4.20933151047e-18
ko04723	Retrograde endocannabinoid signaling	75/1209	175/7206	1.72733715919e-16
ko04020	Calcium signaling pathway	97/1209	265/7206	3.07753141711e-15
ko04725	Cholinergic synapse	68/1209	160/7206	7.75861738549e-15
ko04921	Oxytocin signaling pathway	79/1209	209/7206	1.27771486903e-13
ko04911	Insulin secretion	52/1209	117/7206	1.48434484382e-12
ko04742	Taste transduction	33/1209	61/7206	2.71150836135e-11
ko05031	Amphetamine addiction	42/1209	91/7206	4.87106103547e-11
ko04261	Adrenergic signaling in cardiomyocytes	71/1209	205/7206	2.69268082651e-10
ko04726	Serotonergic synapse	53/1209	137/7206	7.9509381914e-10
ko03010	Ribosome	1/1209	129/7206	2.64302280072e-09
ko04022	cGMP-PKG signaling pathway	71/1209	216/7206	4.58863690176e-09
ko04720	Long-term potentiation	41/1209	99/7206	4.71286832754e-09
ko03040	Spliceosome	3/1209	145/7206	1.54642949584e-08
ko04744	Phototransduction	21/1209	36/7206	1.92884542343e-08
ko04966	Collecting duct acid secretion	17/1209	26/7206	4.07413383981e-08
ko04970	Salivary secretion	38/1209	95/7206	7.64445020888e-08
ko05203	Viral carcinogenesis	17/1209	277/7206	1.0946633345e-07
ko05168	Herpes simplex infection	8/1209	182/7206	3.32935428804e-07
ko05322	Systemic lupus erythematosus	5/1209	151/7206	3.89482909107e-07
ko04964	Proximal tubule bicarbonate reclamation	16/1209	29/7206	2.72995834148e-06
ko05030	Cocaine addiction	29/1209	73/7206	3.77239443758e-06
ko04925	Aldosterone synthesis and secretion	37/1209	105/7206	4.07561366061e-06
ko03013	RNA transport	8/1209	166/7206	4.26175702672e-06
ko04971	Gastric acid secretion	35/1209	98/7206	7.04658571651e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1209	74/7206	1.18579974916e-05
ko04110	Cell cycle	7/1209	145/7206	1.54337426395e-05
ko05164	Influenza A	10/1209	167/7206	3.69764610957e-05
ko04120	Ubiquitin mediated proteolysis	7/1209	138/7206	4.45093253729e-05
ko04922	Glucagon signaling pathway	40/1209	128/7206	6.05365064074e-05
ko04740	Olfactory transduction	28/1209	80/7206	6.30789701565e-05
ko04514	Cell adhesion molecules (CAMs)	40/1209	130/7206	7.09069541497e-05
ko04060	Cytokine-cytokine receptor interaction	13/1209	191/7206	7.15513460388e-05
ko04260	Cardiac muscle contraction	32/1209	98/7206	0.000101584630668
ko04730	Long-term depression	27/1209	78/7206	0.000104156897788
ko03008	Ribosome biogenesis in eukaryotes	2/1209	79/7206	0.000110280715137
ko04141	Protein processing in endoplasmic reticulum	13/1209	184/7206	0.000128491072749
ko04621	NOD-like receptor signaling pathway	10/1209	157/7206	0.000136448351716
ko04010	MAPK signaling pathway	80/1209	321/7206	0.000165215793963
ko04070	Phosphatidylinositol signaling system	35/1209	112/7206	0.000165808270637
ko04745	Phototransduction - fly	16/1209	38/7206	0.000197540316617
ko05140	Leishmaniasis	2/1209	75/7206	0.000250660164181
ko04924	Renin secretion	28/1209	86/7206	0.000365327431839
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1209	79/7206	0.000387450981717
ko04360	Axon guidance	60/1209	233/7206	0.000462750750949
ko04014	Ras signaling pathway	69/1209	279/7206	0.000560521131462
ko04972	Pancreatic secretion	33/1209	111/7206	0.000725923348816
ko05414	Dilated cardiomyopathy	33/1209	112/7206	0.000781715381932
ko00520	Amino sugar and nucleotide sugar metabolism	1/1209	55/7206	0.000836847096124
ko04064	NF-kappa B signaling pathway	5/1209	96/7206	0.000884307730279
ko04072	Phospholipase D signaling pathway	51/1209	197/7206	0.000955356339053
ko04371	Apelin signaling pathway	47/1209	177/7206	0.00100927445329
ko04612	Antigen processing and presentation	3/1209	77/7206	0.00102831125503
ko05110	Vibrio cholerae infection	21/1209	63/7206	0.00109884732237
ko04540	Gap junction	36/1209	128/7206	0.00114092059196
ko05169	Epstein-Barr virus infection	18/1209	206/7206	0.00120091929185
ko05161	Hepatitis B	14/1209	173/7206	0.0012913388336
ko04976	Bile secretion	25/1209	80/7206	0.00130769297853
ko04710	Circadian rhythm	16/1209	43/7206	0.00138556432557
ko04330	Notch signaling pathway	2/1209	62/7206	0.00175920766127
ko04923	Regulation of lipolysis in adipocytes	24/1209	77/7206	0.00178979168808
ko05162	Measles	8/1209	120/7206	0.00183669730562
ko04915	Estrogen signaling pathway	36/1209	131/7206	0.00194678555842
ko04214	Apoptosis - fly	3/1209	72/7206	0.00216444101238
ko00010	Glycolysis / Gluconeogenesis	23/1209	74/7206	0.00246336783647
ko05219	Bladder cancer	1/1209	48/7206	0.00291264674161
ko05166	HTLV-I infection	31/1209	292/7206	0.00303534326997
ko04610	Complement and coagulation cascades	4/1209	79/7206	0.00346708869441
ko04657	IL-17 signaling pathway	5/1209	87/7206	0.00350197929207
ko05321	Inflammatory bowel disease (IBD)	2/1209	56/7206	0.00380839869392
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/1209	59/7206	0.0042016170894
ko03420	Nucleotide excision repair	1/1209	46/7206	0.00447724288253
ko04626	Plant-pathogen interaction	8/1209	18/7206	0.00550657530754
ko00480	Glutathione metabolism	2/1209	55/7206	0.00566070928988
ko05205	Proteoglycans in cancer	29/1209	271/7206	0.00604435341836
ko03022	Basal transcription factors	1/1209	44/7206	0.00692102069635
ko04750	Inflammatory mediator regulation of TRP channels	32/1209	122/7206	0.00699150592071
ko04217	Necroptosis	17/1209	178/7206	0.00795348348597
ko00710	Carbon fixation in photosynthetic organisms	10/1209	27/7206	0.00920019050446
ko05133	Pertussis	6/1209	87/7206	0.00921718086222
ko04622	RIG-I-like receptor signaling pathway	3/1209	62/7206	0.00929910264873
ko05010	Alzheimer's disease	48/1209	202/7206	0.00966241585472
ko05410	Hypertrophic cardiomyopathy (HCM)	27/1209	100/7206	0.00975610219155
ko05200	Pathways in cancer	62/1209	492/7206	0.0102551319068
ko04350	TGF-beta signaling pathway	8/1209	103/7206	0.0111701111564
ko04210	Apoptosis	18/1209	180/7206	0.0114431004319
ko05145	Toxoplasmosis	11/1209	126/7206	0.0114846754687
ko00240	Pyrimidine metabolism	9/1209	110/7206	0.0138755606658
ko05206	MicroRNAs in cancer	18/1209	177/7206	0.0144942030741
ko00190	Oxidative phosphorylation	32/1209	127/7206	0.0158367258742
ko05230	Central carbon metabolism in cancer	22/1209	81/7206	0.0162724644614
ko05131	Shigellosis	6/1209	82/7206	0.017162903885
ko04630	Jak-STAT signaling pathway	12/1209	132/7206	0.0179520174869
ko04115	p53 signaling pathway	5/1209	74/7206	0.0180871507316
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1209	14/7206	0.0195751900072
ko04270	Vascular smooth muscle contraction	37/1209	154/7206	0.0213777367902
ko05222	Small cell lung cancer	7/1209	89/7206	0.0216742560602
ko04658	Th1 and Th2 cell differentiation	8/1209	96/7206	0.0267214958616
ko00562	Inositol phosphate metabolism	23/1209	89/7206	0.0308705632966
ko05217	Basal cell carcinoma	5/1209	68/7206	0.0337786272307
ko00860	Porphyrin and chlorophyll metabolism	1/1209	34/7206	0.0343552911236
ko04510	Focal adhesion	28/1209	240/7206	0.0344717177968
ko00590	Arachidonic acid metabolism	3/1209	52/7206	0.0378879695809
ko04930	Type II diabetes mellitus	15/1209	54/7206	0.0420052927238
ko01524	Platinum drug resistance	6/1209	76/7206	0.0430526652729
ko04146	Peroxisome	8/1209	89/7206	0.0459175863896
ko04142	Lysosome	16/1209	151/7206	0.04663730283