ko pathway ratio_in_study ratio_in_pop p_value ko04922 Glucagon signaling pathway 20/332 128/7206 1.32436483363e-06 ko04745 Phototransduction - fly 10/332 38/7206 5.61103825042e-06 ko04626 Plant-pathogen interaction 7/332 18/7206 8.48150061321e-06 ko00051 Fructose and mannose metabolism 10/332 42/7206 1.48113216001e-05 ko04921 Oxytocin signaling pathway 24/332 209/7206 2.96040094666e-05 ko04713 Circadian entrainment 18/332 136/7206 4.6714904199e-05 ko04070 Phosphatidylinositol signaling system 16/332 112/7206 4.82959729995e-05 ko05230 Central carbon metabolism in cancer 13/332 81/7206 7.30880404566e-05 ko04710 Circadian rhythm 9/332 43/7206 0.000117892650593 ko04020 Calcium signaling pathway 27/332 265/7206 0.000121600721798 ko00010 Glycolysis / Gluconeogenesis 12/332 74/7206 0.000124723350484 ko04720 Long-term potentiation 14/332 99/7206 0.000159726835381 ko05031 Amphetamine addiction 13/332 91/7206 0.000246237308315 ko04925 Aldosterone synthesis and secretion 14/332 105/7206 0.00030026479186 ko01200 Carbon metabolism 15/332 128/7206 0.000754243631866 ko04740 Olfactory transduction 11/332 80/7206 0.00101596314628 ko00620 Pyruvate metabolism 8/332 46/7206 0.00104866898943 ko04066 HIF-1 signaling pathway 14/332 123/7206 0.00149334539108 ko04152 AMPK signaling pathway 17/332 161/7206 0.0015965182976 ko00362 Benzoate degradation 3/332 6/7206 0.00174702000219 ko04114 Oocyte meiosis 15/332 139/7206 0.00176155610502 ko04022 cGMP-PKG signaling pathway 20/332 216/7206 0.00257020791046 ko00030 Pentose phosphate pathway 6/332 32/7206 0.00299591156309 ko05010 Alzheimer's disease 19/332 202/7206 0.00304802963713 ko05214 Glioma 10/332 79/7206 0.00319215800597 ko04261 Adrenergic signaling in cardiomyocytes 19/332 205/7206 0.00338944336942 ko00680 Methane metabolism 6/332 34/7206 0.00411503407882 ko01230 Biosynthesis of amino acids 10/332 85/7206 0.00543600972968 ko00330 Arginine and proline metabolism 8/332 61/7206 0.00650357872174 ko00710 Carbon fixation in photosynthetic organisms 5/332 27/7206 0.00703655301351 ko04970 Salivary secretion 10/332 95/7206 0.011720593476 ko04068 FoxO signaling pathway 15/332 167/7206 0.0130958981421 ko04260 Cardiac muscle contraction 10/332 98/7206 0.0143966122053 ko04971 Gastric acid secretion 10/332 98/7206 0.0143966122053 ko04360 Axon guidance 19/332 233/7206 0.0156166161198 ko00190 Oxidative phosphorylation 12/332 127/7206 0.0161825884401 ko00071 Fatty acid degradation 6/332 45/7206 0.0163235776271 ko00052 Galactose metabolism 5/332 33/7206 0.0165190330171 ko04144 Endocytosis 7/332 342/7206 0.0167948249808 ko04213 Longevity regulating pathway - multiple species 9/332 86/7206 0.0169836170471 ko04924 Renin secretion 9/332 86/7206 0.0169836170471 ko05168 Herpes simplex infection 2/332 182/7206 0.0180030610289 ko00562 Inositol phosphate metabolism 9/332 89/7206 0.0208332381956 ko00500 Starch and sucrose metabolism 5/332 35/7206 0.0209709141225 ko00730 Thiamine metabolism 3/332 14/7206 0.024161212844 ko00982 Drug metabolism - cytochrome P450 5/332 37/7206 0.0261399023139 ko04371 Apelin signaling pathway 15/332 177/7206 0.026469495407 ko04024 cAMP signaling pathway 21/332 279/7206 0.0272181498756 ko04966 Collecting duct acid secretion 4/332 26/7206 0.0296605671433 ko04270 Vascular smooth muscle contraction 13/332 154/7206 0.0305966419581 ko03010 Ribosome 1/332 129/7206 0.0313141328517 ko04930 Type II diabetes mellitus 6/332 54/7206 0.036748347818 ko04910 Insulin signaling pathway 14/332 172/7206 0.0394159345499 ko04919 Thyroid hormone signaling pathway 12/332 143/7206 0.040698064514 ko04015 Rap1 signaling pathway 20/332 278/7206 0.0410333922272 ko04218 Cellular senescence 14/332 177/7206 0.0436978052582 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/332 1/7206 0.0460727171803 ko00564 Glycerophospholipid metabolism 9/332 99/7206 0.0472457814615 ko05322 Systemic lupus erythematosus 2/332 151/7206 0.0485536629832 ko05410 Hypertrophic cardiomyopathy (HCM) 9/332 100/7206 0.048973427318