ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	75/762	152/7206	3.59833364119e-34
ko04080	Neuroactive ligand-receptor interaction	131/762	423/7206	7.07248444171e-33
ko05033	Nicotine addiction	39/762	56/7206	6.13285835293e-26
ko05032	Morphine addiction	53/762	110/7206	9.69193217365e-24
ko04713	Circadian entrainment	57/762	136/7206	1.09188353395e-21
ko04727	GABAergic synapse	50/762	110/7206	4.88409493218e-21
ko04728	Dopaminergic synapse	65/762	185/7206	1.12772163977e-19
ko04723	Retrograde endocannabinoid signaling	62/762	175/7206	5.09597533578e-19
ko04020	Calcium signaling pathway	76/762	265/7206	5.62245632757e-17
ko04720	Long-term potentiation	41/762	99/7206	1.07883617767e-15
ko04921	Oxytocin signaling pathway	61/762	209/7206	3.39257611172e-14
ko04911	Insulin secretion	43/762	117/7206	3.49912948305e-14
ko04024	cAMP signaling pathway	73/762	279/7206	6.39741190528e-14
ko05031	Amphetamine addiction	36/762	91/7206	3.33249114964e-13
ko04725	Cholinergic synapse	50/762	160/7206	4.31242819747e-13
ko04726	Serotonergic synapse	44/762	137/7206	4.03140517384e-12
ko04261	Adrenergic signaling in cardiomyocytes	55/762	205/7206	2.67118215202e-11
ko04721	Synaptic vesicle cycle	31/762	80/7206	2.85056554774e-11
ko04925	Aldosterone synthesis and secretion	36/762	105/7206	4.61289727625e-11
ko04744	Phototransduction	19/762	36/7206	3.50879059272e-10
ko04742	Taste transduction	24/762	61/7206	3.52431710511e-09
ko04070	Phosphatidylinositol signaling system	34/762	112/7206	6.09117720259e-09
ko04970	Salivary secretion	28/762	95/7206	2.688500431e-07
ko04010	MAPK signaling pathway	64/762	321/7206	3.53464241493e-07
ko04022	cGMP-PKG signaling pathway	48/762	216/7206	4.12589348218e-07
ko04745	Phototransduction - fly	16/762	38/7206	4.9534018011e-07
ko05168	Herpes simplex infection	2/762	182/7206	5.30303366147e-07
ko04730	Long-term depression	24/762	78/7206	8.07539925509e-07
ko05030	Cocaine addiction	23/762	73/7206	8.57963762988e-07
ko04740	Olfactory transduction	24/762	80/7206	1.3476904866e-06
ko04072	Phospholipase D signaling pathway	42/762	197/7206	8.86807734204e-06
ko03010	Ribosome	1/762	129/7206	1.57899793046e-05
ko04971	Gastric acid secretion	25/762	98/7206	1.99322698645e-05
ko03040	Spliceosome	2/762	145/7206	2.70986380979e-05
ko04915	Estrogen signaling pathway	30/762	131/7206	3.63937523865e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	20/762	74/7206	5.50888682442e-05
ko04750	Inflammatory mediator regulation of TRP channels	28/762	122/7206	6.93008632659e-05
ko00562	Inositol phosphate metabolism	22/762	89/7206	0.0001482623104
ko04110	Cell cycle	3/762	145/7206	0.00017074152442
ko04060	Cytokine-cytokine receptor interaction	6/762	191/7206	0.000184865425295
ko05203	Viral carcinogenesis	12/762	277/7206	0.000202832260313
ko04972	Pancreatic secretion	25/762	111/7206	0.000233281508931
ko04540	Gap junction	27/762	128/7206	0.000389594494119
ko05322	Systemic lupus erythematosus	4/762	151/7206	0.000415013884099
ko04630	Jak-STAT signaling pathway	3/762	132/7206	0.000495139153877
ko05169	Epstein-Barr virus infection	8/762	206/7206	0.000744363168677
ko04912	GnRH signaling pathway	25/762	122/7206	0.000950825140651
ko04922	Glucagon signaling pathway	26/762	128/7206	0.00113919771547
ko05164	Influenza A	6/762	167/7206	0.00132535329815
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/762	79/7206	0.0013554422339
ko04260	Cardiac muscle contraction	21/762	98/7206	0.0013607188502
ko05162	Measles	3/762	120/7206	0.0014442017623
ko04626	Plant-pathogen interaction	7/762	18/7206	0.00160621808351
ko03013	RNA transport	6/762	166/7206	0.00190094118661
ko04924	Renin secretion	19/762	86/7206	0.00204521807779
ko04114	Oocyte meiosis	26/762	139/7206	0.00322224355714
ko04141	Protein processing in endoplasmic reticulum	8/762	184/7206	0.00331580540448
ko04514	Cell adhesion molecules (CAMs)	25/762	130/7206	0.00344846943761
ko04621	NOD-like receptor signaling pathway	6/762	157/7206	0.00349600751635
ko04014	Ras signaling pathway	45/762	279/7206	0.00375678455692
ko05140	Leishmaniasis	1/762	75/7206	0.00392938303575
ko04371	Apelin signaling pathway	31/762	177/7206	0.0041756115079
ko05414	Dilated cardiomyopathy	22/762	112/7206	0.00454180862569
ko04510	Focal adhesion	13/762	240/7206	0.00719867759772
ko05214	Glioma	16/762	79/7206	0.00906469322487
ko05034	Alcoholism	38/762	238/7206	0.00961998203818
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/762	14/7206	0.0115728792111
ko04930	Type II diabetes mellitus	12/762	54/7206	0.0117229999445
ko04610	Complement and coagulation cascades	2/762	79/7206	0.0151958539516
ko03008	Ribosome biogenesis in eukaryotes	2/762	79/7206	0.0151958539516
ko05205	Proteoglycans in cancer	17/762	271/7206	0.0156354991382
ko04966	Collecting duct acid secretion	7/762	26/7206	0.0156797470281
ko04270	Vascular smooth muscle contraction	26/762	154/7206	0.016134455788
ko04015	Rap1 signaling pathway	42/762	278/7206	0.016538861037
ko04071	Sphingolipid signaling pathway	27/762	162/7206	0.0189544699237
ko05110	Vibrio cholerae infection	13/762	63/7206	0.0203696091498
ko04918	Thyroid hormone synthesis	16/762	86/7206	0.0209981148354
ko05410	Hypertrophic cardiomyopathy (HCM)	18/762	100/7206	0.0210409139197
ko00310	Lysine degradation	2/762	73/7206	0.0213336759784
ko00680	Methane metabolism	8/762	34/7206	0.0226324908508
ko04146	Peroxisome	3/762	89/7206	0.0227355575282
ko04810	Regulation of actin cytoskeleton	17/762	264/7206	0.0245086576706
ko00512	Mucin type O-glycan biosynthesis	7/762	29/7206	0.0281749217422
ko05202	Transcriptional misregulation in cancer	11/762	188/7206	0.0302261603163
ko03320	PPAR signaling pathway	2/762	69/7206	0.030308698389
ko05132	Salmonella infection	4/762	98/7206	0.0309962734413
ko04670	Leukocyte transendothelial migration	8/762	151/7206	0.0316043312466
ko00230	Purine metabolism	30/762	194/7206	0.0322548393001
ko04657	IL-17 signaling pathway	3/762	87/7206	0.0327269872073
ko05231	Choline metabolism in cancer	22/762	134/7206	0.0327578509119
ko04916	Melanogenesis	23/762	142/7206	0.037299196075
ko00240	Pyrimidine metabolism	5/762	110/7206	0.0404797657001
ko00515	Mannose type O-glycan biosynthesis	6/762	25/7206	0.0420570841436
ko04064	NF-kappa B signaling pathway	4/762	96/7206	0.0428461306749
ko05161	Hepatitis B	10/762	173/7206	0.043873976412
ko05131	Shigellosis	3/762	82/7206	0.0443389508743
ko05200	Pathways in cancer	39/762	492/7206	0.0482041899344