ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	156/945	423/7206	6.54489479035e-38
ko04724	Glutamatergic synapse	71/945	152/7206	1.63388875331e-24
ko05033	Nicotine addiction	40/945	56/7206	1.25486829071e-23
ko04020	Calcium signaling pathway	93/945	265/7206	8.67486537346e-21
ko04713	Circadian entrainment	59/945	136/7206	1.38841017702e-18
ko05032	Morphine addiction	49/945	110/7206	3.35528549731e-16
ko04723	Retrograde endocannabinoid signaling	62/945	175/7206	2.13070942871e-14
ko04727	GABAergic synapse	46/945	110/7206	5.00716111857e-14
ko04728	Dopaminergic synapse	62/945	185/7206	3.86485055027e-13
ko04921	Oxytocin signaling pathway	67/945	209/7206	5.7084043955e-13
ko04024	cAMP signaling pathway	79/945	279/7206	5.98794186898e-12
ko04725	Cholinergic synapse	53/945	160/7206	3.45131372801e-11
ko04911	Insulin secretion	43/945	117/7206	5.82570560182e-11
ko04721	Synaptic vesicle cycle	34/945	80/7206	6.14810648993e-11
ko04970	Salivary secretion	36/945	95/7206	8.12843980991e-10
ko04726	Serotonergic synapse	45/945	137/7206	1.4706314425e-09
ko04022	cGMP-PKG signaling pathway	61/945	216/7206	2.03321476806e-09
ko04720	Long-term potentiation	36/945	99/7206	3.03352355954e-09
ko05031	Amphetamine addiction	34/945	91/7206	3.70631609358e-09
ko04261	Adrenergic signaling in cardiomyocytes	57/945	205/7206	1.25086699077e-08
ko04971	Gastric acid secretion	34/945	98/7206	3.28592226537e-08
ko04742	Taste transduction	25/945	61/7206	5.19200425398e-08
ko03010	Ribosome	1/945	129/7206	4.62012351798e-07
ko03040	Spliceosome	2/945	145/7206	6.00452732685e-07
ko04925	Aldosterone synthesis and secretion	33/945	105/7206	1.07756070781e-06
ko05203	Viral carcinogenesis	12/945	277/7206	1.08157932492e-06
ko04730	Long-term depression	26/945	78/7206	3.22965883373e-06
ko04922	Glucagon signaling pathway	36/945	128/7206	7.15481195155e-06
ko04745	Phototransduction - fly	16/945	38/7206	8.90095493894e-06
ko05168	Herpes simplex infection	6/945	182/7206	9.92628765898e-06
ko05164	Influenza A	5/945	167/7206	1.19610391645e-05
ko04070	Phosphatidylinositol signaling system	32/945	112/7206	1.27261239201e-05
ko05322	Systemic lupus erythematosus	4/945	151/7206	1.33973224154e-05
ko04110	Cell cycle	4/945	145/7206	2.83666041581e-05
ko04260	Cardiac muscle contraction	28/945	98/7206	5.18344477015e-05
ko04710	Circadian rhythm	16/945	43/7206	5.59080689793e-05
ko05162	Measles	3/945	120/7206	9.66751937534e-05
ko04630	Jak-STAT signaling pathway	4/945	132/7206	0.000121188750949
ko05169	Epstein-Barr virus infection	10/945	206/7206	0.000135448368176
ko05030	Cocaine addiction	22/945	73/7206	0.000136970257504
ko04072	Phospholipase D signaling pathway	45/945	197/7206	0.000149653623269
ko05014	Amyotrophic lateral sclerosis (ALS)	22/945	74/7206	0.0001585962165
ko03013	RNA transport	7/945	166/7206	0.00016730086388
ko04010	MAPK signaling pathway	65/945	321/7206	0.000252573386921
ko04120	Ubiquitin mediated proteolysis	5/945	138/7206	0.000289315032509
ko00010	Glycolysis / Gluconeogenesis	21/945	74/7206	0.000402581795577
ko04371	Apelin signaling pathway	40/945	177/7206	0.000417359611122
ko04750	Inflammatory mediator regulation of TRP channels	30/945	122/7206	0.000574130563776
ko05161	Hepatitis B	9/945	173/7206	0.000854718148886
ko04270	Vascular smooth muscle contraction	35/945	154/7206	0.000969769597033
ko04014	Ras signaling pathway	56/945	279/7206	0.00104229174963
ko04626	Plant-pathogen interaction	8/945	18/7206	0.00110102094165
ko04540	Gap junction	30/945	128/7206	0.00129961458367
ko04740	Olfactory transduction	21/945	80/7206	0.00131320689745
ko04972	Pancreatic secretion	27/945	111/7206	0.00151704450365
ko04960	Aldosterone-regulated sodium reabsorption	13/945	41/7206	0.00159162056522
ko01230	Biosynthesis of amino acids	22/945	85/7206	0.00167180442365
ko03008	Ribosome biogenesis in eukaryotes	2/945	79/7206	0.00216248278457
ko04964	Proximal tubule bicarbonate reclamation	10/945	29/7206	0.00272229912128
ko05140	Leishmaniasis	2/945	75/7206	0.00313054060357
ko04060	Cytokine-cytokine receptor interaction	12/945	191/7206	0.00314907937918
ko04924	Renin secretion	21/945	86/7206	0.00355254843179
ko04930	Type II diabetes mellitus	15/945	54/7206	0.00361957045436
ko04657	IL-17 signaling pathway	3/945	87/7206	0.00367840543021
ko04621	NOD-like receptor signaling pathway	9/945	157/7206	0.0038304727434
ko04214	Apoptosis - fly	2/945	72/7206	0.0045432135452
ko04550	Signaling pathways regulating pluripotency of stem cells	10/945	165/7206	0.00480194451304
ko05166	HTLV-I infection	23/945	292/7206	0.00586299689463
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/945	14/7206	0.00589032559329
ko05410	Hypertrophic cardiomyopathy (HCM)	23/945	100/7206	0.00647462068797
ko05414	Dilated cardiomyopathy	25/945	112/7206	0.00671552876639
ko04350	TGF-beta signaling pathway	5/945	103/7206	0.00796815380512
ko04514	Cell adhesion molecules (CAMs)	28/945	130/7206	0.00803584200439
ko00680	Methane metabolism	10/945	34/7206	0.00967231433159
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/945	59/7206	0.0101027721706
ko05130	Pathogenic Escherichia coli infection	3/945	77/7206	0.0105261629478
ko04612	Antigen processing and presentation	3/945	77/7206	0.0105261629478
ko04141	Protein processing in endoplasmic reticulum	13/945	184/7206	0.0108070887059
ko04620	Toll-like receptor signaling pathway	5/945	100/7206	0.0109356146684
ko05222	Small cell lung cancer	4/945	89/7206	0.0109372215213
ko05010	Alzheimer's disease	39/945	202/7206	0.0109582483772
ko00240	Pyrimidine metabolism	6/945	110/7206	0.0146021710922
ko05215	Prostate cancer	6/945	111/7206	0.0148946373065
ko04966	Collecting duct acid secretion	8/945	26/7206	0.0150664697698
ko04212	Longevity regulating pathway - worm	4/945	87/7206	0.0153665313026
ko00562	Inositol phosphate metabolism	20/945	89/7206	0.0162614347769
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/945	79/7206	0.0174069265986
ko04973	Carbohydrate digestion and absorption	11/945	42/7206	0.0195213099646
ko05230	Central carbon metabolism in cancer	18/945	81/7206	0.0199492919725
ko04064	NF-kappa B signaling pathway	5/945	96/7206	0.0209665206166
ko05110	Vibrio cholerae infection	15/945	63/7206	0.0219251971237
ko04915	Estrogen signaling pathway	26/945	131/7206	0.0260747454157
ko05321	Inflammatory bowel disease (IBD)	2/945	56/7206	0.0281516270548
ko04015	Rap1 signaling pathway	49/945	278/7206	0.0291541758614
ko04360	Axon guidance	42/945	233/7206	0.0294981809216
ko04217	Necroptosis	14/945	178/7206	0.0327096133146
ko00362	Benzoate degradation	3/945	6/7206	0.0330796555428
ko01200	Carbon metabolism	25/945	128/7206	0.0345345579557
ko04918	Thyroid hormone synthesis	18/945	86/7206	0.0365446906727
ko01524	Platinum drug resistance	4/945	76/7206	0.039591638475
ko00520	Amino sugar and nucleotide sugar metabolism	2/945	55/7206	0.0415982350297
ko05416	Viral myocarditis	2/945	55/7206	0.0415982350297
ko05200	Pathways in cancer	50/945	492/7206	0.0447389108015
ko05145	Toxoplasmosis	9/945	126/7206	0.0452537436392