ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	114/510	423/7206	1.66168604263e-39
ko04724	Glutamatergic synapse	54/510	152/7206	5.36036565546e-25
ko05033	Nicotine addiction	33/510	56/7206	2.83111530937e-24
ko04727	GABAergic synapse	37/510	110/7206	1.60201672845e-16
ko04723	Retrograde endocannabinoid signaling	45/510	175/7206	7.37512599267e-15
ko05032	Morphine addiction	35/510	110/7206	7.59552201517e-15
ko04721	Synaptic vesicle cycle	29/510	80/7206	3.55295741902e-14
ko04713	Circadian entrainment	38/510	136/7206	5.75485691514e-14
ko04728	Dopaminergic synapse	45/510	185/7206	6.6785808347e-14
ko04024	cAMP signaling pathway	56/510	279/7206	3.40776222054e-13
ko05031	Amphetamine addiction	26/510	91/7206	3.52859005794e-10
ko04020	Calcium signaling pathway	48/510	265/7206	7.87811305487e-10
ko04921	Oxytocin signaling pathway	41/510	209/7206	1.25181261487e-09
ko04911	Insulin secretion	28/510	117/7206	6.20844680025e-09
ko04720	Long-term potentiation	25/510	99/7206	1.2761575468e-08
ko04725	Cholinergic synapse	33/510	160/7206	1.5098539185e-08
ko05030	Cocaine addiction	21/510	73/7206	1.57855194829e-08
ko04726	Serotonergic synapse	30/510	137/7206	1.63780701109e-08
ko04742	Taste transduction	19/510	61/7206	1.82304816577e-08
ko04010	MAPK signaling pathway	51/510	321/7206	3.60039851286e-08
ko04261	Adrenergic signaling in cardiomyocytes	37/510	205/7206	8.33979770667e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	19/510	74/7206	5.51259683669e-07
ko05203	Viral carcinogenesis	4/510	277/7206	2.09117305331e-05
ko04972	Pancreatic secretion	21/510	111/7206	2.65676077057e-05
ko04970	Salivary secretion	19/510	95/7206	2.85581351275e-05
ko04260	Cardiac muscle contraction	19/510	98/7206	4.49811649627e-05
ko05164	Influenza A	1/510	167/7206	9.63713388018e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	16/510	79/7206	0.000103658574349
ko04550	Signaling pathways regulating pluripotency of stem cells	1/510	165/7206	0.000150353646408
ko04072	Phospholipase D signaling pathway	29/510	197/7206	0.000175030239127
ko05169	Epstein-Barr virus infection	3/510	206/7206	0.000290876900343
ko04730	Long-term depression	15/510	78/7206	0.000309290300159
ko04925	Aldosterone synthesis and secretion	18/510	105/7206	0.000361318894621
ko04971	Gastric acid secretion	17/510	98/7206	0.000453362682816
ko03040	Spliceosome	1/510	145/7206	0.000456113765299
ko05414	Dilated cardiomyopathy	18/510	112/7206	0.00105630282204
ko04141	Protein processing in endoplasmic reticulum	3/510	184/7206	0.00119244071846
ko05110	Vibrio cholerae infection	12/510	63/7206	0.00132629234343
ko04621	NOD-like receptor signaling pathway	2/510	157/7206	0.00138811535945
ko04630	Jak-STAT signaling pathway	1/510	132/7206	0.00154662059638
ko04966	Collecting duct acid secretion	7/510	26/7206	0.00171682914115
ko05168	Herpes simplex infection	3/510	182/7206	0.00175443058269
ko05322	Systemic lupus erythematosus	2/510	151/7206	0.00199079790461
ko04514	Cell adhesion molecules (CAMs)	19/510	130/7206	0.00260105205762
ko04120	Ubiquitin mediated proteolysis	2/510	138/7206	0.00407393424955
ko04022	cGMP-PKG signaling pathway	27/510	216/7206	0.00413236216812
ko05215	Prostate cancer	1/510	111/7206	0.00451961289533
ko04540	Gap junction	18/510	128/7206	0.00457763510178
ko05410	Hypertrophic cardiomyopathy (HCM)	15/510	100/7206	0.00486165134374
ko05205	Proteoglycans in cancer	8/510	271/7206	0.00505785354612
ko04070	Phosphatidylinositol signaling system	16/510	112/7206	0.00765829694721
ko04924	Renin secretion	13/510	86/7206	0.00878588917278
ko05200	Pathways in cancer	21/510	492/7206	0.0104782414535
ko04014	Ras signaling pathway	31/510	279/7206	0.0117687971871
ko04110	Cell cycle	3/510	145/7206	0.0130242338557
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/510	14/7206	0.0140217949984
ko04915	Estrogen signaling pathway	17/510	131/7206	0.0144179154558
ko05231	Choline metabolism in cancer	17/510	134/7206	0.016323654272
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/510	182/7206	0.0180840239058
ko04750	Inflammatory mediator regulation of TRP channels	16/510	122/7206	0.0183068993621
ko04150	mTOR signaling pathway	5/510	184/7206	0.0184433425222
ko04510	Focal adhesion	8/510	240/7206	0.0202369871166
ko04146	Peroxisome	1/510	89/7206	0.0203549833797
ko05222	Small cell lung cancer	1/510	89/7206	0.0203549833797
ko04940	Type I diabetes mellitus	6/510	32/7206	0.0228050115765
ko05166	HTLV-I infection	11/510	292/7206	0.025870086864
ko05145	Toxoplasmosis	3/510	126/7206	0.0342534687019
ko01524	Platinum drug resistance	1/510	76/7206	0.0423637522019
ko04610	Complement and coagulation cascades	1/510	79/7206	0.0432958128428
ko04140	Autophagy - animal	5/510	164/7206	0.0435124813552
ko04668	TNF signaling pathway	3/510	120/7206	0.0470304384104