ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	49/486	145/7206	1.38145309252e-22
ko04110	Cell cycle	49/486	145/7206	1.38145309252e-22
ko03440	Homologous recombination	26/486	41/7206	4.61120994262e-21
ko03460	Fanconi anemia pathway	27/486	51/7206	6.03118266832e-19
ko04111	Cell cycle - yeast	34/486	90/7206	1.03430015407e-17
ko05322	Systemic lupus erythematosus	44/486	151/7206	1.48950463281e-17
ko03013	RNA transport	43/486	166/7206	4.02967387814e-15
ko03030	DNA replication	20/486	38/7206	2.79253250399e-14
ko03008	Ribosome biogenesis in eukaryotes	28/486	79/7206	5.69541909465e-14
ko04113	Meiosis - yeast	24/486	70/7206	8.54407580896e-12
ko05034	Alcoholism	45/486	238/7206	1.33802233941e-10
ko00240	Pyrimidine metabolism	28/486	110/7206	4.56952570452e-10
ko04144	Endocytosis	2/486	342/7206	1.41024574369e-08
ko03410	Base excision repair	14/486	38/7206	7.18724774107e-08
ko04151	PI3K-Akt signaling pathway	5/486	390/7206	3.59272712527e-07
ko03430	Mismatch repair	10/486	22/7206	5.494005595e-07
ko05203	Viral carcinogenesis	41/486	277/7206	1.80830225463e-06
ko04020	Calcium signaling pathway	2/486	265/7206	2.35315407887e-06
ko03420	Nucleotide excision repair	13/486	46/7206	6.58828781136e-06
ko04261	Adrenergic signaling in cardiomyocytes	1/486	205/7206	1.38394791948e-05
ko05010	Alzheimer's disease	1/486	202/7206	2.14554836867e-05
ko03018	RNA degradation	17/486	84/7206	3.47478545839e-05
ko04728	Dopaminergic synapse	1/486	185/7206	7.05921233663e-05
ko04723	Retrograde endocannabinoid signaling	1/486	175/7206	9.81150054836e-05
ko04024	cAMP signaling pathway	5/486	279/7206	0.000208003317638
ko04060	Cytokine-cytokine receptor interaction	2/486	191/7206	0.000334954868215
ko04114	Oocyte meiosis	21/486	139/7206	0.000430755524024
ko04022	cGMP-PKG signaling pathway	3/486	216/7206	0.000444985127457
ko04724	Glutamatergic synapse	1/486	152/7206	0.000463241374574
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/486	182/7206	0.000468453234734
ko04270	Vascular smooth muscle contraction	1/486	154/7206	0.000473216934636
ko05012	Parkinson's disease	1/486	155/7206	0.000482665884838
ko04014	Ras signaling pathway	6/486	279/7206	0.000594380074942
ko04921	Oxytocin signaling pathway	3/486	209/7206	0.000621390183775
ko04371	Apelin signaling pathway	2/486	177/7206	0.000680030370213
ko05166	HTLV-I infection	35/486	292/7206	0.000751258379911
ko04010	MAPK signaling pathway	8/486	321/7206	0.000852302345233
ko03015	mRNA surveillance pathway	15/486	93/7206	0.00128068119283
ko04713	Circadian entrainment	1/486	136/7206	0.00148788810712
ko04931	Insulin resistance	1/486	137/7206	0.00151356749248
ko05152	Tuberculosis	3/486	187/7206	0.00170912908472
ko04725	Cholinergic synapse	2/486	160/7206	0.00204437161671
ko04152	AMPK signaling pathway	2/486	161/7206	0.00207484393377
ko04015	Rap1 signaling pathway	7/486	278/7206	0.00212100695345
ko00190	Oxidative phosphorylation	1/486	127/7206	0.00214255135368
ko04514	Cell adhesion molecules (CAMs)	1/486	130/7206	0.00217510615412
ko03020	RNA polymerase	7/486	29/7206	0.0025765700048
ko05202	Transcriptional misregulation in cancer	24/486	188/7206	0.00269146019714
ko05205	Proteoglycans in cancer	7/486	271/7206	0.00286635593937
ko04750	Inflammatory mediator regulation of TRP channels	1/486	122/7206	0.00312982374217
ko05145	Toxoplasmosis	1/486	126/7206	0.00329400329851
ko04072	Phospholipase D signaling pathway	4/486	197/7206	0.00371927062788
ko04810	Regulation of actin cytoskeleton	7/486	264/7206	0.00386649127609
ko04914	Progesterone-mediated oocyte maturation	15/486	104/7206	0.00461377769508
ko04510	Focal adhesion	6/486	240/7206	0.00543752877027
ko04727	GABAergic synapse	1/486	110/7206	0.00665923041369
ko05032	Morphine addiction	1/486	110/7206	0.00665923041369
ko04611	Platelet activation	3/486	163/7206	0.00669824218248
ko04140	Autophagy - animal	3/486	164/7206	0.00673242681479
ko00230	Purine metabolism	23/486	194/7206	0.00810729289608
ko04380	Osteoclast differentiation	2/486	134/7206	0.00837511808491
ko04726	Serotonergic synapse	2/486	137/7206	0.00862802840975
ko04218	Cellular senescence	21/486	177/7206	0.00954196444636
ko04530	Tight junction	6/486	228/7206	0.00994901380041
ko01200	Carbon metabolism	2/486	128/7206	0.0118914855464
ko05142	Chagas disease (American trypanosomiasis)	2/486	130/7206	0.0120826716768
ko04915	Estrogen signaling pathway	2/486	131/7206	0.0122510107788
ko04630	Jak-STAT signaling pathway	2/486	132/7206	0.0124683887654
ko04142	Lysosome	3/486	151/7206	0.0130467332431
ko05160	Hepatitis C	3/486	153/7206	0.013245659487
ko04910	Insulin signaling pathway	4/486	172/7206	0.0134336584297
ko04971	Gastric acid secretion	1/486	98/7206	0.0140793904375
ko00564	Glycerophospholipid metabolism	1/486	99/7206	0.0141271968241
ko04620	Toll-like receptor signaling pathway	1/486	100/7206	0.0142450838161
ko04115	p53 signaling pathway	11/486	74/7206	0.0157399988012
ko04912	GnRH signaling pathway	2/486	122/7206	0.0168393418763
ko04066	HIF-1 signaling pathway	2/486	123/7206	0.0169440823008
ko04071	Sphingolipid signaling pathway	4/486	162/7206	0.0251917125227
ko03022	Basal transcription factors	7/486	44/7206	0.0264500169367
ko04924	Renin secretion	1/486	86/7206	0.0295515589623
ko05133	Pertussis	1/486	87/7206	0.0296495324318
ko04146	Peroxisome	1/486	89/7206	0.0302500476457
ko04062	Chemokine signaling pathway	6/486	201/7206	0.0309709162093
ko04933	AGE-RAGE signaling pathway in diabetic complications	3/486	135/7206	0.0352079911476
ko04139	Mitophagy - yeast	6/486	37/7206	0.0355763128073
ko04120	Ubiquitin mediated proteolysis	16/486	138/7206	0.0368395668466
ko04721	Synaptic vesicle cycle	1/486	80/7206	0.0426806431517
ko04137	Mitophagy - animal	1/486	82/7206	0.0431557754472
ko05418	Fluid shear stress and atherosclerosis	5/486	173/7206	0.044051573017
ko05206	MicroRNAs in cancer	19/486	177/7206	0.0461977130285
ko04925	Aldosterone synthesis and secretion	2/486	105/7206	0.0472874785426
ko04659	Th17 cell differentiation	2/486	106/7206	0.0477662659394
ko01521	EGFR tyrosine kinase inhibitor resistance	2/486	106/7206	0.0477662659394
ko04540	Gap junction	3/486	128/7206	0.0479218628309