ko pathway ratio_in_study ratio_in_pop p_value ko04710 Circadian rhythm 14/511 43/7206 7.84495262081e-07 ko04137 Mitophagy - animal 17/511 82/7206 4.75049403397e-05 ko04610 Complement and coagulation cascades 16/511 79/7206 0.00010608463563 ko04060 Cytokine-cytokine receptor interaction 28/511 191/7206 0.000253909515063 ko00120 Primary bile acid biosynthesis 7/511 20/7206 0.000297208093945 ko04146 Peroxisome 16/511 89/7206 0.000448160619506 ko04672 Intestinal immune network for IgA production 9/511 37/7206 0.000873328727046 ko03010 Ribosome 1/511 129/7206 0.00145840857353 ko00592 alpha-Linolenic acid metabolism 6/511 19/7206 0.00150889435757 ko04380 Osteoclast differentiation 20/511 134/7206 0.00167564105264 ko04068 FoxO signaling pathway 23/511 167/7206 0.00192025937007 ko03040 Spliceosome 2/511 145/7206 0.00285301384375 ko04110 Cell cycle 2/511 145/7206 0.00285301384375 ko05034 Alcoholism 6/511 238/7206 0.00286793563074 ko03013 RNA transport 3/511 166/7206 0.00335929787948 ko00950 Isoquinoline alkaloid biosynthesis 4/511 10/7206 0.00371766723547 ko00360 Phenylalanine metabolism 5/511 17/7206 0.00531971917136 ko00362 Benzoate degradation 3/511 6/7206 0.00602970249779 ko00350 Tyrosine metabolism 7/511 33/7206 0.00732195186332 ko05203 Viral carcinogenesis 9/511 277/7206 0.00824201934727 ko04650 Natural killer cell mediated cytotoxicity 14/511 97/7206 0.00884372921254 ko04933 AGE-RAGE signaling pathway in diabetic complications 18/511 135/7206 0.00965897413653 ko05150 Staphylococcus aureus infection 7/511 36/7206 0.011903898308 ko00071 Fatty acid degradation 8/511 45/7206 0.0126592181979 ko05230 Central carbon metabolism in cancer 12/511 81/7206 0.0136969753207 ko04138 Autophagy - yeast 12/511 81/7206 0.0136969753207 ko04514 Cell adhesion molecules (CAMs) 17/511 130/7206 0.0140220444655 ko00620 Pyruvate metabolism 8/511 46/7206 0.0144039218883 ko05321 Inflammatory bowel disease (IBD) 9/511 56/7206 0.0160385073828 ko05340 Primary immunodeficiency 6/511 30/7206 0.0169866637458 ko04120 Ubiquitin mediated proteolysis 3/511 138/7206 0.0179774362752 ko04640 Hematopoietic cell lineage 10/511 64/7206 0.0226882036861 ko04922 Glucagon signaling pathway 16/511 128/7206 0.0228646195181 ko00051 Fructose and mannose metabolism 7/511 42/7206 0.0266942300549 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/511 4/7206 0.0273549568126 ko00590 Arachidonic acid metabolism 8/511 52/7206 0.0286925978633 ko03320 PPAR signaling pathway 10/511 69/7206 0.0287871826719 ko04611 Platelet activation 19/511 163/7206 0.0294062404678 ko04919 Thyroid hormone signaling pathway 17/511 143/7206 0.0313466811808 ko04066 HIF-1 signaling pathway 15/511 123/7206 0.0329212571794 ko05323 Rheumatoid arthritis 12/511 89/7206 0.0333914392815 ko04270 Vascular smooth muscle contraction 18/511 154/7206 0.0368210157502 ko05144 Malaria 7/511 45/7206 0.0374485497996 ko00330 Arginine and proline metabolism 9/511 61/7206 0.0379198320063 ko04070 Phosphatidylinositol signaling system 14/511 112/7206 0.0379980079174 ko00010 Glycolysis / Gluconeogenesis 10/511 74/7206 0.0392416959457 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/511 5/7206 0.043470305362 ko04976 Bile secretion 1/511 80/7206 0.0441276766402 ko04745 Phototransduction - fly 6/511 38/7206 0.0490858803472